Stereo-retentive Intramolecular Glycosyl Cross-Coupling: Development, Scope, and Kinetic Isotope Effect Study was written by Yi, Duk;Zhu, Feng;Walczak, Maciej A.. And the article was included in Organic Letters in 2018.HPLC of Formula: 13420-63-8 This article mentions the following:
A series of cyclic C-glycosides were synthesized using the palladium-catalyzed stereo-retentive intramol. glycosylation of aryl iodides by employing a bulky phosphine ligand. A variety of functional groups are tolerated in the reaction, and enantio-enriched anomeric nucleophiles could be coupled without erosion of optical purity. This study offers a unified method to access both cis- and trans-fused rings by capitalizing on the stereo-retentive nature of the Stille reaction. In addition, competition experiments for intermol. and intramol. cross-couplings revealed secondary KIEs of 1.43 and 0.81, resp., suggesting a profoundly different steric congestion at the transition state. In the experiment, the researchers used many compounds, for example, 2-Chloro-6-iodobenzoic acid (cas: 13420-63-8HPLC of Formula: 13420-63-8).
2-Chloro-6-iodobenzoic acid (cas: 13420-63-8) belongs to iodide derivatives. Generally organic iodides can be divided into two classes of alkyl iodides and aryl iodides. Typical reactions of alkyl iodides include nucleophilic substitution, elimination, reduction, and the formation of organometallics. Polyiodoorganic compounds are sometimes employed as X-ray contrast agents, in fluoroscopy, a type of medical imaging. This application exploits the X-ray absorbing ability of the heavy iodine nucleus.HPLC of Formula: 13420-63-8
Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com