Copper-catalyzed synthesis of benzo[d][1,3]dioxin-4-ones via tandem Ar-halogen bond hydroxylation and dichloromethane-based double Williamson etherification was written by Liu, Yunyun;Huang, Meiying;Wei, Li. And the article was included in New Journal of Chemistry in 2017.Recommanded Product: 13420-63-8 This article mentions the following:
The reactions of o-halobenzoic acids, dichloromethane and potassium hydroxide providing benzo[d][1,3]dioxin-4-ones was reported via the catalysis of Cu(OAc)2. Tandem Ar-X (X = I, Br) bond hydroxylation and double Williamson etherification on dichloromethane were involved during the construction of the target products. In the experiment, the researchers used many compounds, for example, 2-Chloro-6-iodobenzoic acid (cas: 13420-63-8Recommanded Product: 13420-63-8).
2-Chloro-6-iodobenzoic acid (cas: 13420-63-8) belongs to iodide derivatives. Organic iodides can be alkyl, alkenyl, or alkynyl, and all of them are very reactive toward with many kinds of nucleophiles. A typical method for synthesis of aromatic iodides is diazotization of primary aromatic amines followed by treatment of potassium iodide. Aliphatic alcohols are converted to alkyl iodides by treating with hydrogen iodide.Recommanded Product: 13420-63-8
Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com