A mild and simple regioselective iodination of activated aromatics with iodine and catalytic ceric ammonium nitrate. [Erratum to document cited in CA146:184189] was written by Das, Biswanath;Krishnaiah, Maddeboina;Venkateswarlu, Katta;Saidi Reddy, V.. And the article was included in Tetrahedron Letters in 2007.Safety of 4-Bromo-2-iodophenol This article mentions the following:
On page 81, right column, paragraph 4, line 1 should read: “To a mixture of an activated arene (0.5 mmol) and molecular iodine (0.5 mmol) in CH3CN (5 mL), CAN (10 mol %) was added.”. In the experiment, the researchers used many compounds, for example, 4-Bromo-2-iodophenol (cas: 207115-22-8Safety of 4-Bromo-2-iodophenol).
4-Bromo-2-iodophenol (cas: 207115-22-8) belongs to iodide derivatives. Generally organic iodides can be divided into two classes of alkyl iodides and aryl iodides. Typical reactions of alkyl iodides include nucleophilic substitution, elimination, reduction, and the formation of organometallics. Iodo alkanes participate in a variety of organic synthesis reactions, which include the Simmons–Smith reaction (cyclopropanation using iodomethane), Williamson ether synthesis, Wittig reaction, Grignard reaction, alkyl coupling reactions, and Wurtz reaction.Safety of 4-Bromo-2-iodophenol
Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com