Author: Jessica.F

Karthigha, S. published the artcileSynthesis, growth, structural, optical and third order nonlinear optical properties of new quinolinium derivative single crystal: 1-ethyl-2-[2-(3,4,5-trimethoxy-phenyl) vinyl]-quinolinium iodide, Computed Properties of 606-55-3, the publication is Journal of Materials Science: Materials in Electronics (2017), 28(18), 13507-13520, database is CAplus.

An organic quinolinium derivative crystal 1-ethyl-2-[2-(3,4,5-trimethoxy-phenyl) vinyl]-quinolinium iodide has been synthesized by knoevenagel condensation reaction and the crystals were grown by solution growth method for the first time. The grown crystal structure was confirmed by single crystal X-ray diffraction anal. and it showed that TMQI crystal belong to the triclinic space group P-1. The mol. structure and composition of the crystal was further confirmed by Fourier transform IR (FT-IR) and NMR (FT-NMR) spectroscopic techniques. The thermal stability of the title crystal has been investigated by TG/DSC curves. The linear optical response of the grown crystal has been examined by using UV-Vis-NIR spectral anal., and the photoluminescence spectrum exhibits strong emission radiation at 558 nm. The chem. etching anal. was carried to reveal the growth pattern of TMQI crystal. Laser induced damage threshold of the title crystal was found to be 1.15 GW/cm². The third order nonlinear optical property of grown crystal was studied using Z-scan technique and the magnitude of third order nonlinear susceptibility has found to be in the order of 10^-3 esu, which is higher than the reported quinolinium derivative crystals.

Journal of Materials Science: Materials in Electronics published new progress about 606-55-3. 606-55-3 belongs to iodides-buliding-blocks, auxiliary class Quinoline,Salt, name is 1-Ethyl-2-methylquinolin-1-ium iodide, and the molecular formula is C12H14IN, Computed Properties of 606-55-3.

Referemce:
https://en.wikipedia.org/wiki/Iodide,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Makane, Vitthal B. published the artcileNovel 1,3,4-oxadiazoles as antitubercular agents with limited activity against drug-resistant tuberculosis, Safety of 4-Iodobenzohydrazide, the publication is Future Medicinal Chemistry (2019), 11(6), 499-510, database is CAplus and MEDLINE.

In recent times, heterocyclic chemotypes are being explored for the development of new antimycobacterials that target the drug-resistant tuberculosis. Here, we are disclosing the 5-substitued 2-mercapto-1,3,4-oxadiazoles I (R₁ = Ph, 2-BrC₆H₄, 4-OHC₆H₄, etc.) as potent antitubercular agents. A small library of 2-mercapto-1,3,4-oxadiazoles I was synthesized using various acids. The compounds were evaluated for antituberculosis activity against M. tuberculosis H37Rv. Compound I (R₁ = 4-OHC₆H₄) was identified as antitubercular lead with MIC of 0.6μg/mL against M. tuberculosis H37Rv. This compound was nontoxic to CHO-K1 cells and showed selectivity index of 39. Of note, I (R₁ = 4-OHC₆H₄) showed antitubercular activity against pre-extensively drug-resistant clin. isolate of Mycobacterium with MIC of 2μg/mL. This study provides potent antitubercular agent which can be further optimized to discover novel antibiotics.

Future Medicinal Chemistry published new progress about 39115-95-2. 39115-95-2 belongs to iodides-buliding-blocks, auxiliary class Iodide,Hydrazine,Amine,Benzene,Hydrazide,Amide, name is 4-Iodobenzohydrazide, and the molecular formula is C7H7IN2O, Safety of 4-Iodobenzohydrazide.

Referemce:
https://en.wikipedia.org/wiki/Iodide,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Tatevosyan, Stepan S. published the artcileFacile Access to Triazole-Fused 3,1-Benzoxazines Enabled by Metal-Free Base-Promoted Intramolecular C-O Coupling, Related Products of iodides-buliding-blocks, the publication is Synthesis (2022), 54(2), 369-377, database is CAplus.

A convenient approach to assemble 1,2,3-triazole-fused 4 H-3,1-benzoxazines I (R = H, 6-Me, 7-I, 7,8-dimethoxy, etc.; R¹ = H, Me, Ph; R² = Bu, cyclopropyl, Ph, etc.) has been developed. Diverse alc.-tethered 5-iodotriazoles II (R³ = H, 6-Me, 5-I, 4,5-dimethoxy, etc.), readily accessible by a modified protocol of Cu-catalyzed (3+2)-cycloaddition, were utilized as precursors of the target fused heterocycles I. The intramol. C-O coupling proceeded efficiently under base-mediated transition-metal-free conditions, furnishing cyclization products I in yields up to 96%. Suppression of the competing reductive cleavage of the C-I bond was achieved by the use of Na₂CO₃ in acetonitrile at 100°C. This practical and cost-effective procedure features a broad substrate scope and valuable functional group tolerance.

Synthesis published new progress about 53279-83-7. 53279-83-7 belongs to iodides-buliding-blocks, auxiliary class Iodide,Amine,Benzene,Alcohol, name is (2-Amino-5-iodophenyl)methanol, and the molecular formula is C13H10F2, Related Products of iodides-buliding-blocks.

Referemce:
https://en.wikipedia.org/wiki/Iodide,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Uegaki, Hiroko published the artcileLiving radical polymerization of acrylates with rhenium(V)-based initiating systems: ReO₂I(PPh₃)₂/Alkyl Iodide, Computed Properties of 31253-08-4, the publication is ACS Symposium Series (2000), 196-206, database is CAplus.

Rhenium(V) iododioxobis(triphenylphosphine) [ReO₂I(PPh₃)₂], a group 7 transition metal complex, induced living radical polymerizations of Me and Bu acrylates in conjunction with an iodide initiator such as CH₃CH(Ph)I and (CH₃)₂C(CO₂Et)I in the presence of Al(Oi-Pr)₃, where the reaction was faster than the NiBr₂(Pn-Bu₃)₂-mediated. The number-average mol. weights of the obtained polymers increased in direct proportion to monomer conversion, and the mol. weight distributions were relatively narrow throughout the polymerizations (M_w/M_n ∼ 1.6). The polymerization most probably proceeds via the rhenium-catalyzed homolytic cleavage of the polymer C-I terminal originated from the iodide initiator, as indicated by the ¹H NMR anal. of the polymer terminal structure and quenching study of the polymerization with a stable nitroxide radical. In contrast, a bromide initiator like CCl₃Br led to an uncontrolled acrylate polymerization with the rhenium(V) complex. The iodide/ReO₂I(PPh₃)₂ initiating system also induced a fast polymerization of Me methacrylate, though the polymerization was not controlled.

ACS Symposium Series published new progress about 31253-08-4. 31253-08-4 belongs to iodides-buliding-blocks, auxiliary class Iodide,Ester, name is Ethyl 2-Iodopropionate, and the molecular formula is C9H6BrNO, Computed Properties of 31253-08-4.

Referemce:
https://en.wikipedia.org/wiki/Iodide,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Stambirskyi, Maksym V. published the artcilePhosphine Oxides (-POMe₂) for Medicinal Chemistry: Synthesis, Properties, and Applications, Recommanded Product: 4-Iodo-1-methyl-1H-pyrazol-5-amine, the publication is Journal of Organic Chemistry (2021), 86(18), 12783-12801, database is CAplus and MEDLINE.

A general practical approach to hetero(aromatic) and aliphatic P(O)Me₂-substituted derivatives is elaborated. The key synthetic step was a [Pd]-mediated C-P coupling of (hetero)aryl bromides/iodides with HP(O)Me₂. The P(O)Me₂ substituent was shown to dramatically increase solubility and decrease lipophilicity of organic compounds This tactic was used to improve the solubility of the antihypertensive drug prazosin without affecting its biol. profile.

Journal of Organic Chemistry published new progress about 1443278-79-2. 1443278-79-2 belongs to iodides-buliding-blocks, auxiliary class Pyrazole,Iodide,Amine, name is 4-Iodo-1-methyl-1H-pyrazol-5-amine, and the molecular formula is C10H9ClN2O, Recommanded Product: 4-Iodo-1-methyl-1H-pyrazol-5-amine.

Referemce:
https://en.wikipedia.org/wiki/Iodide,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Abu El-Hamd, R. M. published the artcileSynthesis, visible spectral studies and biological activity of some new heterocyclic quinone trimethine and merocyanine dyes, Synthetic Route of 606-55-3, the publication is Indian Journal of Heterocyclic Chemistry (1996), 5(4), 305-310, database is CAplus.

New asym. cyanine dyes (I; A = α-picolinyl, quinaldinyl, γ-picolinyl; Z = S, O; II; A = as above; III; R = COMe, CO₂Et; and IV) incorporating naphthoquinone in conjunction with thiazole/oxazole and/or oxadiazine moieties were prepared Mol. complex formation with ethanol was verified by mixed solvent studies. The variation of absorbance with pH was utilized for the determination of the pKa value for a selected dye. Bactericidal and fungicidal activity of selected cyanines were determined

Indian Journal of Heterocyclic Chemistry published new progress about 606-55-3. 606-55-3 belongs to iodides-buliding-blocks, auxiliary class Quinoline,Salt, name is 1-Ethyl-2-methylquinolin-1-ium iodide, and the molecular formula is C12H14IN, Synthetic Route of 606-55-3.

Referemce:
https://en.wikipedia.org/wiki/Iodide,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Shindy, H. A. published the artcileSyntheses and absorption-structure relationships of some new photosensitizer cyanine dyes, Recommanded Product: 1-Ethyl-2-methylquinolin-1-ium iodide, the publication is Proceedings – Indian Academy of Sciences, Chemical Sciences (2002), 114(2), 125-136, database is CAplus.

3-Methyl-1,4-diphenyl-1H-pyrazolo[4,5-d][1,3]oxazol-5-one was synthesized as starting material to prepare new photosensitizing mono-, tri-, and substituted triazadimethine and mixed cyanine dyes. Absorption-structure relationships of the synthesized cyanine dyes were determined by studying their electronic spectral behavior in ethanol. The structures of the dyes were identified by elemental anal. and IR and ¹H NMR spectral data.

Proceedings – Indian Academy of Sciences, Chemical Sciences published new progress about 606-55-3. 606-55-3 belongs to iodides-buliding-blocks, auxiliary class Quinoline,Salt, name is 1-Ethyl-2-methylquinolin-1-ium iodide, and the molecular formula is C6H6N2O, Recommanded Product: 1-Ethyl-2-methylquinolin-1-ium iodide.

Referemce:
https://en.wikipedia.org/wiki/Iodide,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Shindy, H. A. published the artcileNew cyanine dyes from 4,9-dioxopiperidino[2,3-g]-1,2,3,4,6,7,8,9-octahydroquinolinoquinone, Computed Properties of 606-55-3, the publication is Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry (2001), 40B(5), 426-429, database is CAplus.

Sym. bis(styryl, tetramethine, azastyryl) cyanine dyes containing arylidene, heterylidene, and schiff base moieties have been obtained by the interaction of 4,9-dioxopiperidino[2,3-g]-1,2,3,4,6,7,8,9-octahydroquinolinoquinone with aromatic aldehyde, heterocyclic aldehyde and nitroso compounds followed by condensation with 2(4)-Me quaternary ethiodide salts. The UV spectra in 95% ethanol of all the synthesized cyanine dyes show that the photosensitization of the dyes increases (or decreases) by increasing (or decreasing) conjugation, by the presence of electron donating (attracting) groups and the more (less) planarity of the dyes. The new compounds have been identified by elemental anal. and IR and ¹H NMR spectral data.

Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry published new progress about 606-55-3. 606-55-3 belongs to iodides-buliding-blocks, auxiliary class Quinoline,Salt, name is 1-Ethyl-2-methylquinolin-1-ium iodide, and the molecular formula is C6H13I, Computed Properties of 606-55-3.

Referemce:
https://en.wikipedia.org/wiki/Iodide,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

El-Aal, R. M. Abd published the artcileSynthesis, absorption spectra studies and biological activity of some novel conjugated dyes, COA of Formula: C12H14IN, the publication is Journal of the Chinese Chemical Society (Taipei) (2000), 47(2), 389-395, database is CAplus.

Novel monomethine, dimethine, and tetramethine cyanine dyes were prepared as conjugated dyes. Such dyes incorporated coumarin and/or quinoline derivatives These dyes were synthesized to study their spectral behavior, solvatochromism, and biol. activity. These dyes were characterized by elemental anal. and IR, ¹H NMR, and mass spectra.

Journal of the Chinese Chemical Society (Taipei) published new progress about 606-55-3. 606-55-3 belongs to iodides-buliding-blocks, auxiliary class Quinoline,Salt, name is 1-Ethyl-2-methylquinolin-1-ium iodide, and the molecular formula is C12H14IN, COA of Formula: C12H14IN.

Referemce:
https://en.wikipedia.org/wiki/Iodide,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Abed El-Aal, R. M. published the artcileSynthesis and photophysics in organic solvents of mesosubstituted pentamethine and related metal complexes cyanine dyes, Computed Properties of 606-55-3, the publication is Dyes and Pigments (2002), 54(2), 121-129, database is CAplus.

The reaction in a ratio of 1 mol of diacetylchloromethane with 1 mol of heterocyclic nitrogen bases afforded N-substituted heterocyclidinium ylide halides. Reaction at a ratio of 1 mol of ylides with 2 and 3 mol of 2(4)-methylheterocyclic quaternary salts in basic catalyst afforded meso-substituted pentamethine and monomethine meso-substituted pentamethine cyanine dyes, resp. Reaction of equimolar ratios of metal chloride adducts of the ylides with equi- (bi)molar ratios of 2(4)-methylheterocyclic quaternary salts in basic medium afforded asym. (sym.) meso-substituted mono- (bis)monomethine metal complex cyanine dyes. Elemental analyses and IR and ¹H NMR spectral data confirmed the structures of the newly synthesized compounds The electronic absorption spectra of these dyes in ethanol and their photophysics in different solvents are discussed.

Dyes and Pigments published new progress about 606-55-3. 606-55-3 belongs to iodides-buliding-blocks, auxiliary class Quinoline,Salt, name is 1-Ethyl-2-methylquinolin-1-ium iodide, and the molecular formula is C12H14IN, Computed Properties of 606-55-3.

Referemce:
https://en.wikipedia.org/wiki/Iodide,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com