Author: Jessica.F

Mitra, Sudha Sumi published the artcilePolyhalide derivatives of poly[N-(2-aminoethyl)acrylamido]triethylammonium resins as iodinating reagents, Application In Synthesis of 105752-04-3, the main research area is polyacrylamide ammonium polyhalide iodinating reagent preparation; aryl amine iodination polyacrylamide ammonium polyhalide; phenol iodination polyacrylamide ammonium polyhalide; regioselective iodinating reagent aromatic amine phenol; iodo arene preparation.

Poly[N-(2-aminoethyl)acrylamido]triethylammonium dichloroiodate, tetrachloroiodate, and dibromoiodate resins are useful for selective iodination of aromatic amines and phenols. The influence of the various reaction parameters including nature of the solvent, effective molar concentration of the reagent, and temperature were investigated to find out optimum reaction conditions for achieving selectivity for monoiodination.

Macromolecular Chemistry and Physics published new progress about Aryl halides Role: SPN (Synthetic Preparation), PREP (Preparation). 105752-04-3 belongs to class iodides-buliding-blocks, name is 4-Iodo-3-nitroaniline, and the molecular formula is C6H5IN2O2, Application In Synthesis of 105752-04-3.

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Patil, Arvind M. published the artcile2-methoxyethanol, a remarkably efficient and alternative reaction medium for iodination of reactive aromatics using iodine and iodic acid, SDS of cas: 105752-04-3, the main research area is aromatic iodination iodine iodic acid methoxyethanol; aryl iodide preparation solvent effect green chem.

Remarkably effective iodination of reactive aromatics carried out using iodine and iodic acid in 2-methoxyethanol as an efficient and alternative reaction medium. The comparison was made by carrying out iodination reaction in acetic acid and ethanol. The 2-methoxyethanol is excellent reaction solvent in terms of clean reaction conditions, short reaction time giving quant. yields of product and no need of further purification

Orbital: The Electronic Journal of Chemistry published new progress about Aromatic hydrocarbons Role: RCT (Reactant), RACT (Reactant or Reagent). 105752-04-3 belongs to class iodides-buliding-blocks, name is 4-Iodo-3-nitroaniline, and the molecular formula is C6H5IN2O2, SDS of cas: 105752-04-3.

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Shinde, Avinash T. published the artcileA practical iodination of aromatic compounds by using iodine and iodic acid, Recommanded Product: 4-Iodo-3-nitroaniline, the main research area is aromatic iodination iodine iodic acid; aryl iodide preparation.

This article described simple and efficient method for the iodination of different aromatic amines, hydroxy aromatic aldehydes, hydroxy acetophenones and phenols using iodine and iodic acid in ethanol as a solvent. Notable advantages include mild reaction condition, no need of catalyst, short reaction time, simple practical procedure, giving excellent yield of the product.

Synthetic Communications published new progress about Aromatic compounds Role: RCT (Reactant), RACT (Reactant or Reagent). 105752-04-3 belongs to class iodides-buliding-blocks, name is 4-Iodo-3-nitroaniline, and the molecular formula is C6H5IN2O2, Recommanded Product: 4-Iodo-3-nitroaniline.

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Misal, Balu published the artcileSulfated polyborate-H2O assisted tunable activation of N-iodosuccinimide for expeditious mono and diiodination of arenes, Application In Synthesis of 21784-73-6, the main research area is arene iodosuccinimide sulfated polyborate catalyst regioselective iodination; iodoarene preparation.

Owing to both Lewis and Bronsted acid active sites on sulfated polyborate under homogeneous conditions, iodination protocol of arenes was developed, which can meet the requirement of regioselectivity and higher yield. The sulfated polyborate activated N-iodosuccinimide for mono iodination of highly activated substrates viz. phenols, anilines under anhydrous condition. Water tuned sulfated polyborate to generate more Bronsted acid sites resulting in rapid activation of NIS for diiodination. The protocol was equally applicable to diiodination of 4-hydroxyphenylacetic acid to synthesize 4-hydroxy-3,5-diiodophenylacetic acid, an intermediate of tiratricol, a thyroid treatment drug. This protocol was further integrated via one-pot sequential iodination and Sonogashira coupling to synthesize aryl acetylenes, building blocks for the synthesis of a variety of specialty chems., API and natural products.

Tetrahedron Letters published new progress about Aromatic hydrocarbons Role: RCT (Reactant), RACT (Reactant or Reagent). 21784-73-6 belongs to class iodides-buliding-blocks, name is 4-Iodo-2-nitrophenol, and the molecular formula is C6H4INO3, Application In Synthesis of 21784-73-6.

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Seath, Ciaran P. published the artcileSynthesis of 2-BMIDA 6,5-bicyclic heterocycles by Cu(I)/Pd(0)/Cu(II) cascade catalysis of 2-iodoaniline/phenols, Recommanded Product: 3-Iodo-5-nitropyridin-2-amine, the main research area is BMIDA bicyclic heterocycle preparation; iodoaniline boronic acid MIDA ester heterocyclization copper palladium catalyst.

A one-pot cascade reaction for the synthesis of 2-BMIDA 6,5-bicyclic heterocycles has been developed using Cu(II)/Pd(0)/Cu(II) catalysis. 2-Iodoanilines and phenols undergo a Cu(I)/Pd(0)-catalyzed Sonogashira reaction with ethynyl BMIDA followed by in situ Cu(II)-catalyzed 5-endo-dig cyclization to generate heterocyclic scaffolds with a BMIDA functional group in the 2-position. The method provides efficient access to borylated indoles, benzofurans, and aza-derivatives, which can be difficult to access through alternative methods.

Chemical Communications (Cambridge, United Kingdom) published new progress about Heterocyclic compounds, nitrogen Role: RCT (Reactant), SPN (Synthetic Preparation), RACT (Reactant or Reagent), PREP (Preparation). 25391-56-4 belongs to class iodides-buliding-blocks, name is 3-Iodo-5-nitropyridin-2-amine, and the molecular formula is C5H4IN3O2, Recommanded Product: 3-Iodo-5-nitropyridin-2-amine.

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Albadi, Jalal published the artcileRegioselective iodination of aromatic compounds with potassium iodide in the presence of benzyltriphenylphosphonium perchlorate, Application In Synthesis of 21784-73-6, the main research area is regioselective iodination aromatic compound potassium iodide benzyltriphenylphosphonium perchlorate.

A simple and efficient method for the selective iodination of various aromatic compounds by using potassium iodide in the presence of benzyltriphenylphosphonium perchlorate, is reported. This method provides several advantages such as good selectivity between ortho and para positions of aromatic compounds and high yields of the products.

Chinese Chemical Letters published new progress about Iodination, regioselective. 21784-73-6 belongs to class iodides-buliding-blocks, name is 4-Iodo-2-nitrophenol, and the molecular formula is C6H4INO3, Application In Synthesis of 21784-73-6.

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Xia, Guoqin published the artcileLigand-Enabled β-Methylene C(sp3)-H Arylation of Masked Aliphatic Alcohols, SDS of cas: 685517-67-3, the main research area is methylene arylation aliphatic alc salicylic directing group pyridone ligand; C−H activation; aliphatic alcohols; directing groups; ligands; synthetic methods.

Despite recent advances, reactivity and site-selectivity remain significant obstacles for the practical application of C(sp3)-H bond functionalization methods. Here, we describe a system that combines a salicylic-aldehyde-derived L,X-type directing group with an electron-deficient 2-pyridone ligand to enable the β-methylene C(sp3)-H arylation of aliphatic alcs., which has not been possible previously. Notably, this protocol is compatible with heterocycles embedded in both alc. substrates and aryl coupling partners. A site- and stereo-specific annulation of dihydrocholesterol and the synthesis of a key intermediate of englitazone illustrate the practicality of this method.

Angewandte Chemie, International Edition published new progress about Arylation. 685517-67-3 belongs to class iodides-buliding-blocks, name is 2,6-Difluoro-3-iodopyridine, and the molecular formula is C5H2F2IN, SDS of cas: 685517-67-3.

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Reitti, Marcus published the artcileSynthesis of Phenols and Aryl Silyl Ethers via Arylation of Complementary Hydroxide Surrogates, Related Products of iodides-buliding-blocks, the main research area is diaryliodonium salt silanol arylation; hydrogen peroxide diaryliodonium salt arylation; aryl silyl ether preparation; phenol preparation.

Two transition-metal-free methods to access substituted phenols via the arylation of silanols or hydrogen peroxide with diaryliodonium salts are presented. The complementary reactivity of the two nucleophiles allows synthesis of a broad range of phenols without competing aryne formation, as illustrated by the synthesis of the anesthetic Propofol. Furthermore, silyl-protected phenols can easily be obtained, which are suitable for further transformations.

Organic Letters published new progress about Alkynes, arynes Role: RCT (Reactant), SPN (Synthetic Preparation), RACT (Reactant or Reagent), PREP (Preparation). 2100-25-6 belongs to class iodides-buliding-blocks, name is 3-Iodo-1,2,4,5-tetramethylbenzene, and the molecular formula is C10H13I, Related Products of iodides-buliding-blocks.

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Lu, Xi published the artcileNickel-Catalyzed Defluorinative Reductive Cross-Coupling of gem-Difluoroalkenes with Unactivated Secondary and Tertiary Alkyl Halides, Name: Benzyl 3-iodoazetidine-1-carboxylate, the main research area is arylfluoroalkene chemoselective diastereoselective preparation; nickel imidazolinylpyridine catalyst defluorinative reductive coupling aryldifluoroalkene bromoalkane iodoalkane; secondary tertiary bromoalkane chloroalkane reductive coupling aryldifluoroalkene nickel catalyst.

In the presence of Ni(cod)2 and an imidazolinylpyridine ligand, 1,1-difluoroalkenes such as I underwent chemoselective and diastereoselective reductive defluorinative coupling reactions with secondary alkyl bromides and iodides such as iodocyclohexane mediated by bis(pinacolato)diboron and tripotassium phosphate to yield (Z)-arylfluoroalkenes such as II in 36-95% yields and in 8:1->50:1 Z:E diastereoselectivities; the reaction was also used to couple difluoroalkenes with primary alkyl iodides and 1,1-difluoroalkyl bromides using a catalyst generated from NiBr2(diglyme) and 4,7-dimethoxy-1,10-phenanthroline.

Journal of the American Chemical Society published new progress about Bromoalkanes Role: RCT (Reactant), RACT (Reactant or Reagent). 939759-26-9 belongs to class iodides-buliding-blocks, name is Benzyl 3-iodoazetidine-1-carboxylate, and the molecular formula is C11H12INO2, Name: Benzyl 3-iodoazetidine-1-carboxylate.

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Reddy, K. Suresh Kumar published the artcileIodination of aromatic compounds using potassium iodide and hydrogen peroxide, Recommanded Product: 4-Iodo-2-nitrophenol, the main research area is arene regioselective iodination potassium iodide hydrogen peroxide; aryl iodide green preparation.

A simple, efficient, regioselective, and eco-friendly method for oxy-iodination of aromatic compounds is presented. In this method, the electrophilic substitutions of iodine generated in situ from KI as an iodine source and H2O2 as an O source were employed without any catalyst/mineral acid.

Synthetic Communications published new progress about Aryl iodides Role: SPN (Synthetic Preparation), PREP (Preparation). 21784-73-6 belongs to class iodides-buliding-blocks, name is 4-Iodo-2-nitrophenol, and the molecular formula is C6H4INO3, Recommanded Product: 4-Iodo-2-nitrophenol.

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com