Author: Jessica.F

Kalay, Erbay; Kilic, Hamdullah; Catir, Mustafa; Cakici, Murat; Kazaz, Cavit published an article in 2014, the title of the article was Generation of singlet oxygen (1O2) from hydrogen peroxide decomposition by in situ generated hypervalent iodoarene reagents.Quality Control of 1,3,5,7-Tetrakis(4-iodophenyl)adamantane And the article contains the following content:

A novel method for the production of singlet oxygen from H2O2 was developed. A combination of iodoarene (ArI), methyltrioxorhenium (MTO), and H2O2 in the presence of pyridine as the co-catalyst efficiently produced singlet mol. oxygen (1O2) under biphasic conditions. The existence of 1O2 was demonstrated by trapping experiments with aromatic dienes, 1,3-cyclodienes, and alkenes. The mechanism of 1O2 production from the iodoarene/MTO/35 % H2O2 system and the reaction scope was also discussed. The experimental process involved the reaction of 1,3,5,7-Tetrakis(4-iodophenyl)adamantane(cas: 144970-30-9).Quality Control of 1,3,5,7-Tetrakis(4-iodophenyl)adamantane

The Article related to hypervalent iodoarene oxygen generation hydrogen peroxide decomposition, Catalysis, Reaction Kinetics, and Inorganic Reaction Mechanisms: Catalytic Reactions and other aspects.Quality Control of 1,3,5,7-Tetrakis(4-iodophenyl)adamantane

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

On June 30, 2017, Vainer, A. Ya.; Dyumaev, K. M.; Kovalenko, A. M.; Berenshtein, L. E.; Krichevskaya, S. A.; Fridzon, R. Z. published an article.Related Products of 144970-30-9 The title of the article was Tetrasubstituted adamantanes as frameworks in the design of assemblies of porphyrin macrocycles. And the article contained the following:

A strategy for the synthesis of adamantane-containing polyphenols of a porphyrin series was suggested on the basis of Suzuki-Miyaura reaction between 1,3,5,7-tetrakis(4′-iodophenyl)adamantane and a monoboryl derivative of substituted porphyrin. The synthesis of this porphyrin assembly on the adamantane core followed by chem. transformations of this compound was provided a possibility to synthesize the corresponding polyphenol derivative The latter was used in the development of pos. photoresists for nanolithog. with exposure to radiation at a wavelength 13.5 nm capable of producing topol. structures with a resolution of 16 nm. The experimental process involved the reaction of 1,3,5,7-Tetrakis(4-iodophenyl)adamantane(cas: 144970-30-9).Related Products of 144970-30-9

The Article related to tetradimethoxyphenyl porphyrinylphenyl adamantane preparation, tetrapolyhydroxyphenyl porphyrinylphenyl adamantane preparation pos photoresist nanolithog, Heterocyclic Compounds (More Than One Hetero Atom): Eight- and Higher-Membered Rings and other aspects.Related Products of 144970-30-9

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

On September 30, 2017, Inamori, Daiki; Miwa, Takuya; Fujihara, Tetsuaki; Tsuji, Yasushi; Terao, Jun published an article.Name: 1H-Imidazolium, 1,3-bis[4-iodo-2,6-bis(1-methylethyl)phenyl]-, chloride (1:1) The title of the article was Thieme Chemistry Journals Awardees – Where Are They Now? Synthesis of a Dinuclear Copper NHC Complex Bearing a Rigid 蟺-Conjugated Cyclic Framework. And the article contained the following:

Macrocyclic dinuclear complexes have been gaining popularity in the design of homogeneous catalysts. Herein, we report the design of such a complex featuring catalytically active sites fixed inside the ring and its synthesis using a cross-coupling reaction. The experimental process involved the reaction of 1H-Imidazolium, 1,3-bis[4-iodo-2,6-bis(1-methylethyl)phenyl]-, chloride (1:1)(cas: 934008-48-7).Name: 1H-Imidazolium, 1,3-bis[4-iodo-2,6-bis(1-methylethyl)phenyl]-, chloride (1:1)

The Article related to copper macrocycle heterocyclic carbene conjugation preparation optimized structure, Organometallic and Organometalloidal Compounds: Groups Ib, Iib – Cu, Ag, Au, Zn, Cd, Hg and other aspects.Name: 1H-Imidazolium, 1,3-bis[4-iodo-2,6-bis(1-methylethyl)phenyl]-, chloride (1:1)

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

On April 12, 2010, Chun, Jiseul; Lee, Han Sol; Jung, Il Gu; Lee, Soon Won; Kim, Hae Jin; Son, Seung Uk published an article.Quality Control of 1H-Imidazolium, 1,3-bis[4-iodo-2,6-bis(1-methylethyl)phenyl]-, chloride (1:1) The title of the article was Cu2O: A Versatile Reagent for Base-Free Direct Synthesis of NHC-Copper Complexes and Decoration of 3D-MOF with Coordinatively Unsaturated NHC-Copper Species. And the article contained the following:

A new and direct synthetic route for N-heterocyclic carbene (NHC)-copper complexes was disclosed by heating imidazolium halides with Cu2O. The related synthetic procedure was quite simple and the product easily separable from the reaction mixture by simple filtration. Ultimately, this reaction was successfully applied to decorate three-dimensional(3D)-metal organic framework (MOFs) with coordinatively unsaturated NHC-copper species. The experimental process involved the reaction of 1H-Imidazolium, 1,3-bis[4-iodo-2,6-bis(1-methylethyl)phenyl]-, chloride (1:1)(cas: 934008-48-7).Quality Control of 1H-Imidazolium, 1,3-bis[4-iodo-2,6-bis(1-methylethyl)phenyl]-, chloride (1:1)

The Article related to copper oxide versatile reagent nhc carbene complex, imidazolium halide reaction copper monoxide, crystal mol structure copper cerium imidazolidene carbene complex, Organometallic and Organometalloidal Compounds: Groups Ib, Iib – Cu, Ag, Au, Zn, Cd, Hg and other aspects.Quality Control of 1H-Imidazolium, 1,3-bis[4-iodo-2,6-bis(1-methylethyl)phenyl]-, chloride (1:1)

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

On April 17, 2008, Petillo, Peter A.; Kaufman, Michael D.; Flynn, Daniel L. published a patent.COA of Formula: C9H8ClIO2 The title of the patent was Preparation of urea derivatives as kinase inhibitors useful for the treatment of myleoproliferative diseases and other proliferative diseases. And the patent contained the following:

Title compounds I [Q1 and Q2 independently = N or CZ6; E1 = cycloalkyl, pyrrolidinyl, piperidinyl, etc.; A = (un)substituted Ph, furyl, thienyl, etc.; X2 = alkyl or bond; X3 = CO, O, (un)substituted alkoxy, etc.; R3 independently = H, alkyl, carbocyclyl, and substituted phenyl; Z6 independently = H, alkyl, OH, hydroxyalkyl, etc.; m = 1-3] are prepared and disclosed for treatment of hyperproliferative diseases and mammalian cancers, especially human cancers. Thus, e.g., II was prepared by coupling of 2,2,2-trichloroethyl 3-tert-butyl-1-(quinolin-6-yl)-1H-pyrazol-5-ylcarbamate (preparation given) with 4-(4-amino-3-fluorophenoxy)-N-methylpicolinamide (preparation given). Assays were described for evaluating binding of I to various kinases, e.g., II demonstrated an IC50 value of 4 nM in the p-Abl kinase assay. The invention also pertains to methods of modulating kinase activities, pharmaceutical compositions, and methods of treating individuals, incorporating or using the compounds The experimental process involved the reaction of Ethyl 5-chloro-2-iodobenzoate(cas: 1012882-90-4).COA of Formula: C9H8ClIO2

The Article related to urea derivative preparation kinase inhibitor, Aliphatic Compounds: Ureas, Carbamic Acids, Guanidines, and Their Sulfur-Containing Analogs and other aspects.COA of Formula: C9H8ClIO2

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

On September 7, 2010, Flynn, Daniel L.; Petillo, Peter A.; Kaufman, Michael D. published a patent.Electric Literature of 1012882-90-4 The title of the patent was Preparation of urea derivatives as kinase inhibitors useful for the treatment of myeloproliferative diseases and other proliferative diseases. And the patent contained the following:

Title compounds I [E1 = (un)substituted Ph; A = (un)substituted imidazolyl or pyrazolyl; X2 = bond; X3 = O; each R3 independently = H, alkyl, carbocyclyl, etc.; each Z6 independently = H, alkyl, hydroxyalkyl, etc.; m = 1-3] are prepared and disclosed for treatment of myeloproliferative diseases and other proliferative diseases. Thus, e.g., II was prepared by coupling of 2,2,2-trichloroethyl 3-tert-butyl-1-(quinolin-6-yl)-1H-pyrazol-5-ylcarbamate (preparation given) with 4-(4-amino-3-fluorophenoxy)-N-methylpicolinamide (preparation given). Select I were evaluated in Abl kinase and T315I Abl kinase assays (data given). The experimental process involved the reaction of Ethyl 5-chloro-2-iodobenzoate(cas: 1012882-90-4).Electric Literature of 1012882-90-4

The Article related to urea derivative preparation myeloproliferative proliferative disease, Aliphatic Compounds: Ureas, Carbamic Acids, Guanidines, and Their Sulfur-Containing Analogs and other aspects.Electric Literature of 1012882-90-4

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

On March 14, 2013, Flynn, Daniel L.; Petillo, Peter A.; Kaufman, Michael D. published a patent.Recommanded Product: 1012882-90-4 The title of the patent was Preparation of heterocyclic urea derivatives as kinase inhibitors useful for the treatment of myeloproliferative diseases and other proliferative diseases. And the patent contained the following:

Compounds of the invention (I, wherein E1 is substituted phenyl; A is substituted pyrazolyl and imidazolyl; X2 is a direct bond, wherein E1 is directly linked to the NH group; X3 is -O-; Z6 is independently and individually selected from H, C1-6 alkyl, branched C3-7 alkyl, hydroxy, etc.; t = 1-3) find utility in the treatment of of cancer, secondary cancer growth arising from metastasis, hyperproliferative diseases, diseases characterized by hyper-vascularization, inflammation, osteoarthritis, respiratory diseases, stroke, systemic shock, immunol. diseases, autoimmune diseases, bone resorptive diseases, cardiovascular disease and diseases characterized by angiogenesis. The invention also provides a method of modulating a kinase activity of a wild-type kinase species, oncogenic forms thereof, aberrant fusion proteins thereof and polymorphs of any of the foregoing, by contacting said species with a compound I. Synthetic procedures for preparing I are exemplified. Thus, e.g., II was prepared by coupling of 2,2,2-trichloroethyl 3-tert-butyl-1-(quinolin-6-yl)-1H-pyrazol-5-ylcarbamate (preparation given) with 4-(4-amino-3-fluorophenoxy)-N-methylpicolinamide (preparation given). Assays were described for evaluating binding of I to various kinases, e.g., II demonstrated an IC50 value of 4 nM in the p-Abl kinase assay. The experimental process involved the reaction of Ethyl 5-chloro-2-iodobenzoate(cas: 1012882-90-4).Recommanded Product: 1012882-90-4

The Article related to preparation heterocyclic urea derivative kinase inhibitor treatment myeloproliferative disease, Aliphatic Compounds: Ureas, Carbamic Acids, Guanidines, and Their Sulfur-Containing Analogs and other aspects.Recommanded Product: 1012882-90-4

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

On September 6, 2012, Flynn, Daniel L.; Kaufman, Michael D. published a patent.HPLC of Formula: 1012882-90-4 The title of the patent was Preparation of heterocyclic urea derivatives as kinase inhibitors useful for the treatment of hyperproliferative and other diseases. And the patent contained the following:

Compounds of the present invention (I, wherein E1 is substituted phenyl; A is substituted pyrazolyl and imidazolyl; X2 is a direct bond, wherein E1 is directly linked to the NH group; X3 is -O-; Z6 is independently and individually selected from H, C1-6 alkyl, branched C3-7 alkyl, hydroxy, etc.; t = 1-3), alone and in combination with other active agents, find utility in the treatment of hyperproliferative diseases, mammalian cancers and especially human cancers including but not limited to for example malignant melanomas, myeloproliferative diseases, chronic myelogenous leukemia, acute lymphocytic leukemia, a disease caused by c-ABL kinase, oncogenic forms thereof, aberrant fusion proteins thereof and polymorphs thereof. More generally the invention relates to a method of treating mammalian disease with I wherein the disease etiol. or progression is at least partially mediated by the kinase activity of c-ABL kinase, BCR-ABL kinase, FLT-3 kinase, TIE-2 kinase, TRK-A kinase, TRK-B kinase, TRK-C kinase, VEGFR-2 kinases, c-MET kinase, PDGFR-alpha kinase, PDGFR-beta kinase, HER-1 kinase, HER-2 kinase, HER-3 kinase, HER-4 kinase, FGFR kinases, c-KIT kinase, RET kinase, c-FMS kinase, oncogenic forms thereof, aberrant fusion proteins thereof and polymorphs of any of the foregoing. Synthetic procedures for preparing I are exemplified. Thus, e.g., II was prepared by coupling of 2,2,2-trichloroethyl 3-tert-butyl-1-(quinolin-6-yl)-1H-pyrazol-5-ylcarbamate (preparation given) with 4-(4-amino-3-fluorophenoxy)-N-methylpicolinamide (preparation given). Assays were described for evaluating binding of I to various kinases, e.g., II demonstrated an IC50 value of 4 nM in the p-Abl kinase assay. The experimental process involved the reaction of Ethyl 5-chloro-2-iodobenzoate(cas: 1012882-90-4).HPLC of Formula: 1012882-90-4

The Article related to preparation heterocyclic urea derivative kinase inhibitor treatment hyperproliferative disease, Aliphatic Compounds: Ureas, Carbamic Acids, Guanidines, and Their Sulfur-Containing Analogs and other aspects.HPLC of Formula: 1012882-90-4

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

On January 2, 2015, Shi, Guangfa; Shao, Changdong; Pan, Shulei; Yu, Jingxun; Zhang, Yanghui published an article.Computed Properties of 364-12-5 The title of the article was Silver-Catalyzed C-H Trifluoromethylation of Arenes Using Trifluoroacetic Acid as the Trifluoromethylating Reagent. And the article contained the following:

Direct trifluoromethylation of arenes using TFA as the trifluoromethylating reagent was achieved with Ag as the catalyst. This reaction not only provides a new protocol for aryl C-H trifluoromethylation, but the generation of CF3路 from TFA may prove useful in other contexts and could potentially be extended to other trifluoromethylation reactions. The experimental process involved the reaction of 5-Bromo-2-iodobenzotrifluoride(cas: 364-12-5).Computed Properties of 364-12-5

The Article related to silver catalyst trifluoromethylation arene trifluoroacetic acid, carbon hydrogen bond activation green chem, Benzene, Its Derivatives, and Condensed Benzenoid Compounds: Halides and Halonium Compounds and other aspects.Computed Properties of 364-12-5

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

On November 16, 2018, Ormerod, Dominic; Dorbec, Matthieu; Merkul, Eugen; Kaval, Nadya; Lefevre, Nicolas; Hostyn, Steven; Eykens, Lies; Lievens, Jo; Sergeyev, Sergey; Maes, Bert U. W. published an article.Recommanded Product: 1H-Imidazolium, 1,3-bis[4-iodo-2,6-bis(1-methylethyl)phenyl]-, chloride (1:1) The title of the article was Synthesis of Pd Complexes Containing Tailed NHC Ligands and Their Use in a Semicontinuous Membrane-Assisted Suzuki Cross-Coupling Process. And the article contained the following:

Homogeneous catalysis has proved to be a reliable method for preparing numerous mol. entities, but catalysts can be expensive and difficult to remove. Because of this, industry targets catalysts that are easily separated and recovered and feature increased turnover numbers The ongoing shift from multipurpose batch reactors toward continuous manufacturing in fine chems. synthesis results in a new set of catalyst requirements. This paper reports the design and use of Pd complexes suitable for a semicontinuous Suzuki cross-coupling reaction based on a membrane-assisted reactor. These Pd complexes contain tailed N-heterocyclic carbene (NHC) ligands, allowing internal catalyst recovery by organic solvent nanofiltration with top-layer-modified ceramic membranes. These membranes give selective nanofiltration of the catalyst based on a combination of size exclusion and affinity separation (solvent-solute-membrane interactions). The semicontinuous system developed led to significantly improved turnover numbers, simplified product isolation, and consequently reduced mass intensity by simply adding more of the reactants and reagents to the reaction vessel. The experimental process involved the reaction of 1H-Imidazolium, 1,3-bis[4-iodo-2,6-bis(1-methylethyl)phenyl]-, chloride (1:1)(cas: 934008-48-7).Recommanded Product: 1H-Imidazolium, 1,3-bis[4-iodo-2,6-bis(1-methylethyl)phenyl]-, chloride (1:1)

The Article related to palladium nitrogen heterocyclic carbene complex preparation catalyst, semicontinuous membrane assisted suzuki cross coupling palladium catalyst, Organometallic and Organometalloidal Compounds: Group Viii – Co, Ni, Ru, Rh, Pd, Os, Ir, Pt and other aspects.Recommanded Product: 1H-Imidazolium, 1,3-bis[4-iodo-2,6-bis(1-methylethyl)phenyl]-, chloride (1:1)

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com