Author: Jessica.F

The author of 《Straightforward sequential and one-pot synthesis of a pentasaccharide repeating unit corresponding to the cell wall O-antigen of Shigella boydii type 18》 were Shit, Pradip; Gucchait, Arin; Misra, Anup Kumar. And the article was published in Tetrahedron in 2019. Application of 516-12-1 The author mentioned the following in the article:

Synthesis of a pentasaccharide repeating unit corresponding to the cell of wall O-antigen Shigella boydii type 18 has been achieved by sequential as well as iterative glycosylation in one-pot. Use of p-methoxybenzyl group (PMB) as an in situ removable protecting group allowed obtaining the desired pentasaccharide derivative in a generalized glycosylation condition and in one-pot condition. Synthesis of a beta-L-rhamnosidic linkage present in the mol. has been successfully achieved using L-rhamnosyl thioglycoside donor having a picoloyl group at remote C-3 position influencing beta selectivity in the glycosylation. A combination of N-iodosuccinimide (NIS) and perchloric acid supported over silica (HClO4-SiO2) has been used as thiophilic glycosylation promoter in all glycosylation reactions. TEMPO mediated selective oxidation of the primary hydroxyl group has been carried out at the late stage of the synthetic strategy.1-Iodopyrrolidine-2,5-dione(cas: 516-12-1Application of 516-12-1) was used in this study.

1-Iodopyrrolidine-2,5-dione(cas: 516-12-1) is used in the preparation of vinyl sulfones from olefins and benzenesulfinic acid. It acts as a source for I+ and involved in Hunsdiecker reactions for the conversion of cinnamic acids, and propiolic acids to the corresponding alfa-halostyrenes and 1-halo-1-alkynes respectively. Application of 516-12-1

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

The author of 《Immobilization of palladium nanoparticles on Metformin-functionalized graphene oxide as a heterogeneous and recyclable nanocatalyst for Suzuki coupling reactions and reduction of 4-nitrophenol》 were Hemmati, Saba; Mehrazin, Lida; Pirhayati, Mozhgan; Veisi, Hojat. And the article was published in Polyhedron in 2019. Reference of 1-Iodo-4-methylbenzene The author mentioned the following in the article:

In this study, Pd nanoparticles supported on Metformin modified graphene oxide (GO-Met-Pd) is proposed as a green heterogeneous catalyst. The structural properties of the as-synthesized nanocatalyst were determined by X-ray diffraction (XRD), Fourier transformed IR (FT-IR) spectroscopy, transmission electron microscopy (TEM), field emission SEM (FESEM), energy dispersive X-ray spectroscopy (EDS), wavelength-dispersive X-ray spectroscopy (WDX) and inductively coupled plasma (ICP). Activity of the catalyst was investigated by focusing on the Suzuki-Miyaura coupling reaction and room-temperature reduction of 4-nitrophenol (4-NP), as model reactions. The catalyzed reactions provided high yields of biphenyl compounds through the Suzuki-Miyaura reaction and outlined highly efficient conversion of 4-NP to its reduced form. Moreover, no significant Pd leaching was detected in the reaction solutions and the catalyst could be recovered, at least, 6 times without any considerable loss of its catalytic activity. The experimental part of the paper was very detailed, including the reaction process of 1-Iodo-4-methylbenzene(cas: 624-31-7Reference of 1-Iodo-4-methylbenzene)

1-Iodo-4-methylbenzene(cas: 624-31-7) is used in wide range of medicals industrial applications as well as in pharmaceutical intermediates, polarizing films for Liquid Crystal Display (LCD) chemicals.Reference of 1-Iodo-4-methylbenzene

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

《Photocatalytic CO2 reduction of C/ZnO nanofibers enhanced by an Ni-NiS cocatalyst》 was published in Nanoscale in 2020. These research results belong to Deng, Hongzhao; Xu, Feiyan; Cheng, Bei; Yu, Jiaguo; Ho, Wingkei. Safety of 1-Iodopyrrolidine-2,5-dione The article mentions the following:

The photocatalytic reduction of CO2 into valuable hydrocarbon fuels via solar energy is a promising strategy for carbon utilization. In the present paper, a hierarchical Ni-NiS/C/ZnO photocatalyst was prepared via the in situ photodeposition of compact Ni-NiS nanosheets onto C/ZnO electrospun nanofibers. The existence of metallic Ni and NiS was confirmed by XPS. Photoluminescence (PL) and time-resolved PL spectra revealed that the cocatalyst Ni-NiS enhanced the charge separation efficiency of the C/ZnO nanofibers. The as-prepared Ni-NiS/C/ZnO showed enhanced CO2 reduction activity, with CO and CH4 production rates 10 and 15 times greater than those of pristine C/ZnO under 350 W visible light illumination. The intermediates of CH3O-, HCHO, and HCOO- were detected by in situ Fourier transform IR spectroscopy, confirming that CO2 reduction is a complex reaction with multiple steps. The 13C isotopic tracer method proved that CH4 and CO were obtained from the reduction of CO2 rather than from other carbon species in the environment. The amorphous carbon in C/ZnO could promote optical absorption, improve conductivity and reduce the interfacial charge transport resistance. Ni-NiS improved the electron-hole-pair separation of the C/ZnO nanofibers. The observed enhancement in photocatalytic activity was largely attributed to higher light utilization and effective electron-hole separation This work proves that Ni-NiS is a promising cocatalyst to ZnO for photocatalytic CO2 reduction In the experiment, the researchers used many compounds, for example, 1-Iodopyrrolidine-2,5-dione(cas: 516-12-1Safety of 1-Iodopyrrolidine-2,5-dione)

1-Iodopyrrolidine-2,5-dione(cas: 516-12-1) is used in the preparation of vinyl sulfones from olefins and benzenesulfinic acid. It acts as a source for I+ and involved in Hunsdiecker reactions for the conversion of cinnamic acids, and propiolic acids to the corresponding alfa-halostyrenes and 1-halo-1-alkynes respectively. Safety of 1-Iodopyrrolidine-2,5-dione

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

《Dibenzofuran Derivatives Inspired from Cercosporamide as Dual Inhibitors of Pim and CLK1 Kinases》 was written by Dao, Viet Hung; Ourliac-Garnier, Isabelle; Loge, Cedric; McCarthy, Florence O.; Bach, Stephane; da Silva, Teresinha Goncalves; Denevault-Sabourin, Caroline; Thiefaine, Jerome; Baratte, Blandine; Robert, Thomas; Gouilleux, Fabrice; Brachet-Botineau, Marie; Bazin, Marc-Antoine; Marchand, Pascal. HPLC of Formula: 626-02-8 And the article was included in Molecules in 2021. The article conveys some information:

Pim kinases (proviral integration site for Moloney murine leukemia virus kinases) are overexpressed in various types of hematol. malignancies and solid carcinomas, and promote cell proliferation and survival. Thus, Pim kinases are validated as targets for antitumor therapy. In this context, our combined efforts in natural product-inspired library generation and screening furnished very promising dibenzo[b,d]furan derivatives derived from cercosporamide. Among them, lead compound 44 was highlighted as a potent Pim-1/2 kinases inhibitor with an addnl. nanomolar IC50 value against CLK1 (cdc2-like kinases 1) and displayed a low micromolar anticancer potency towards the MV4-11 (AML) cell line, expressing high endogenous levels of Pim-1/2 kinases. The design, synthesis, structure-activity relationship, and docking studies are reported herein and supported by enzyme, cellular assays, and Galleria mellonella larvae testing for acute toxicity. After reading the article, we found that the author used 3-Iodophenol(cas: 626-02-8HPLC of Formula: 626-02-8)

3-Iodophenol(cas: 626-02-8) belongs to organic iodides. The carbon-iodine bond is weaker than other carbon-halogen bonds due to the poor electronegative nature of the iodine atom. In general, organic iodides are light-sensitive and turn yellow during storage, owing to the formation of iodine.HPLC of Formula: 626-02-8

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

You, Shengyong; Zhang, Rongli; Cai, Mingzhong published their research in Synthesis in 2021. The article was titled 《A Magnetically Recyclable Palladium-Catalyzed Formylation of Aryl Iodides with Formic Acid as CO Source: A Practical Access to Aromatic Aldehydes》.Application In Synthesis of 3-Iodophenol The article contains the following contents:

A magnetically recyclable palladium-catalyzed formylation of aryl iodides ArI (Ar = C6H5, 3-pyridyl, 2-furyl, etc.) under CO gas-free conditions has been developed by using a bidentate phosphine ligand-modified magnetic nanoparticles-anchored palladium(II) complex [2P-Fe3O4@SiO2-Pd(OAc)2] as catalyst, yielding a wide variety of aromatic aldehydes ArCHO in moderate to excellent yields. Here, formic acid was employed as both the CO source and the hydrogen donor with iodine and PPh3 as the activators. This immobilized palladium catalyst can be obtained via a simple preparative procedure and facilely recovered simply by using an external magnetic field, and reused at least 9 times without any apparent loss of catalytic activity. In the experimental materials used by the author, we found 3-Iodophenol(cas: 626-02-8Application In Synthesis of 3-Iodophenol)

3-Iodophenol(cas: 626-02-8) belongs to organic iodides. The carbon-iodine bond is weaker than other carbon-halogen bonds due to the poor electronegative nature of the iodine atom. Application In Synthesis of 3-Iodophenol Alkyl iodides react at a faster rate than alkyl fluorides due to the weak C-I bond.

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Wen, Si; Tian, Qingyu; Chen, Yanhui; Zhang, Yuqing; Cheng, Guolin published their research in Organic Letters in 2021. The article was titled 《Annulation of CF3-Imidoyl Sulfoxonium Ylides with 1,3-Dicarbonyl Compounds: Access to 1,2,3-Trisubstituted 5-Trifluoromethylpyrroles》.Category: iodides-buliding-blocks The article contains the following contents:

A lithium-bromide-promoted nucleophilic substitution/annulation cascade reaction between CF3-imidoyl sulfoxonium ylides and 1,3-dicarbonyl compounds was established and the corresponding 1,2,3-trisubstituted 5-trifluoromethylpyrroles was obtained in 27-78% yield. This reaction features a broad substrate scope and generated DMSO and H2O as byproducts. After reading the article, we found that the author used Trimethylsulfoxonium iodide(cas: 1774-47-6Category: iodides-buliding-blocks)

Trimethylsulfoxonium iodide(cas: 1774-47-6) reacts with sodium hydride to prepare dimethyloxosulfonium methylide, which is used as a methylene-transfer reagent in synthetic chemistry. It is used to prepare ylide, which reacts with carbonyl compounds to get epoxides. Further, it reacts with alfa,beta-unsaturated esters to get cyclopropyl esters.Category: iodides-buliding-blocks

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Hong, Chao; Yu, Shuling; Liu, Zhanxiang; Zhang, Yuhong published an article in 2021. The article was titled 《Rhodium(III)-catalyzed annulation of enamides with sulfoxonium ylides toward isoquinolines》, and you may find the article in RSC Advances.Synthetic Route of C3H9IOS The information in the text is summarized as follows:

An efficient rhodium(III)-catalyzed C-H activation followed by intermol. annulation between enamides and sulfoxonium ylides had been developed. The transformation proceeded smoothly with a broad range of substrates, affording a series of isoquinoline derivatives I [R = Ph, 4-BrC6H4, 2-furyl, etc.; R1 = H, 6-F, 8-MeO, etc; R2 = H, Me, Ph] in moderate to good yields under additive-free conditions. In addition to this study using Trimethylsulfoxonium iodide, there are many other studies that have used Trimethylsulfoxonium iodide(cas: 1774-47-6Synthetic Route of C3H9IOS) was used in this study.

Trimethylsulfoxonium iodide(cas: 1774-47-6) reacts with sodium hydride to prepare dimethyloxosulfonium methylide, which is used as a methylene-transfer reagent in synthetic chemistry. It is used to prepare ylide, which reacts with carbonyl compounds to get epoxides.Synthetic Route of C3H9IOS

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

In 2022,Smolkin, Boris; Levi, Noam; Chen, Ravit published an article in ACS Omega. The title of the article was 《Efficient Decontamination of HD by an Electrophilic Iodine/Carboxylate Composite as an Active Sorbent》.HPLC of Formula: 516-12-1 The author mentioned the following in the article:

The development of new and efficient decontamination methods has become more relevant in recent years, especially with regard to solid-based decontamination and detoxification systems. The majority of powders used today are dealing with the phys. adsorption of chem. warfare agents (CWAs) and their removal from sites without actively destroying them. In this work, we have designed and developed an active solid composite matrix combining organic carboxylate salts and N-iodosuccinimide (NIS) for HD decontamination via oxidation All the reactions and mechanistic studies for the sorption and degradation of CWAs were conducted using direct polarization and cross polarization solid-state magic-angle spinning NMR techniques. Performance toward the sorption and detoxification of HD was tested, exhibiting oxidation within minutes in a mild and selective manner to the nontoxic sulfoxide derivative followed by visible formation of iodine. The results indicate that carboxylate moieties in the matrix are important for stabilizing the pos. charged sulfonium ion intermediate and for supplying oxygen for hydrolysis in a water-deficient environment. The NaOBz/NIS composite was shown to be the most efficient in sorbing and converting the water-insoluble agent HD to its nontoxic, water-soluble sulfoxide, which could then be removed from the site with mere water, resulting in less environmental damage and quick remediation. In the experiment, the researchers used many compounds, for example, 1-Iodopyrrolidine-2,5-dione(cas: 516-12-1HPLC of Formula: 516-12-1)

1-Iodopyrrolidine-2,5-dione(cas: 516-12-1) is used in the preparation of vinyl sulfones from olefins and benzenesulfinic acid. It acts as a source for I+ and involved in Hunsdiecker reactions for the conversion of cinnamic acids, and propiolic acids to the corresponding alfa-halostyrenes and 1-halo-1-alkynes respectively. HPLC of Formula: 516-12-1

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

In 2022,Das, Ashis; Buzzetti, Luca; Purins, Mikus; Waser, Jerome published an article in ACS Catalysis. The title of the article was 《Palladium-Catalyzed trans-Hydroalkoxylation: Counterintuitive Use of an Aryl Iodide Additive to Promote C-H Bond Formation》.Application In Synthesis of 1-Chloro-3-iodobenzene The author mentioned the following in the article:

Authors report an enantioselective palladium-catalyzed trans-hydroalkoxylation of propargylic amines with a trifluoroacetaldehyde-derived tether to build chiral oxazolidines. Diastereoselective hydrogenation using a heterogeneous palladium catalyst then gave access to protected benzylic amino alcs. in 45-87% yields and 84-94% ee values. Hydroalkoxylation of the alkynes required a catalytic amount of aryl iodide, highlighting the counterintuitive key role played by a putative Pd(II)/ArI oxidative addition complex to promote oxypalladation/protodemetalation. In the experiment, the researchers used many compounds, for example, 1-Chloro-3-iodobenzene(cas: 625-99-0Application In Synthesis of 1-Chloro-3-iodobenzene)

1-Chloro-3-iodobenzene(cas: 625-99-0) belongs to organic iodides. Generally organic iodides can be divided into two classes of alkyl iodides and aryl iodides. Typical reactions of alkyl iodides include nucleophilic substitution, elimination, reduction, and the formation of organometallics.Application In Synthesis of 1-Chloro-3-iodobenzeneHalogenation of aromatic hydrocarbons is a very important reaction via an electrophilic aromatic substitution.

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

In 2022,Li, Zhijun; Zhang, Mingyang; Zhang, Lili; Dong, Xiuli; Leng, Leipeng; Horton, J. Hugh; Wang, Jun published an article in Nano Research. The title of the article was 《Engineering the atomic interface of porous ceria nanorod with single palladium atoms for hydrodehalogenation reaction》.Name: 3-Iodophenol The author mentioned the following in the article:

Tuning the electronic properties of single atom catalysts (SACs) between the central metal and the neighboring surface atoms has emerged as an efficient strategy to boost catalytic efficiency and metal utilization. Here we describe a simple and efficient approach to create atomically dispersed palladium atoms supported over defect-contg porous ceria nanorod contg palladium up to 0.26 weight The existence of singly dispersed palladium atoms is confirmed by spherical aberration correction electron microscopy and extended X-ray absorption fine structure measurements. This catalyst shows excellent efficiency in hydrodehalogenation reactions at low H2 pressure under mild conditions, along with satisfactory recyclability and scalability. D. functional theory (DFT) calculations reveal that the high activity stems from the spatial isolation of palladium atoms and the modified electronic structure of palladium confined in defect-containing ceria nanorod. This work may lay the foundation for the facile creation of single atom catalysts within the synthetic community and shed light on the possibility for scale-up prodn graphic not available see fulltext. The results came from multiple reactions, including the reaction of 3-Iodophenol(cas: 626-02-8Name: 3-Iodophenol)

3-Iodophenol(cas: 626-02-8) belongs to organic iodides. Generally organic iodides can be divided into two classes of alkyl iodides and aryl iodides. Typical reactions of alkyl iodides include nucleophilic substitution, elimination, reduction, and the formation of organometallics.Name: 3-IodophenolHalogenation of aromatic hydrocarbons is a very important reaction via an electrophilic aromatic substitution.

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com