Author: Jessica.F

In 2019,Organic Letters included an article by Gou, Bo-Bo; Liu, Hang-Fan; Chen, Jie; Zhou, Ling. Recommanded Product: 1-Bromo-3-iodobenzene. The article was titled 《Palladium-Catalyzed Site-Selective C(sp3)-H Arylation of Phenylacetaldehydes》. The information in the text is summarized as follows:

A Pd-catalyzed selective C-H arylation reaction of phenylacetaldehydes using L-valine as the transient directing group, is described.. This process showed a broad substrate scope and excellent selectivity in which a ligand-controlled functionalization of the unactivated β-C(sp3)-H bond. In addition, enantioselective arylation of phenylacetaldehydes was preliminarily explored by utilizing a bulky chiral transient directing group. In the part of experimental materials, we found many familiar compounds, such as 1-Bromo-3-iodobenzene(cas: 591-18-4Recommanded Product: 1-Bromo-3-iodobenzene)

1-Bromo-3-iodobenzene(cas: 591-18-4) has been used in the preparation of 1-(3′-bromophenyl)-3,3,4,4,5,5,6,6,7,7,8,8,9,9,10,10,10-heptadecafluorodec-1-ene and 1-(3′-bromophenyl)-3,3,4,4,5,5,6,6,7,7,8,8,8-tridecafluorooct-1-ene.Recommanded Product: 1-Bromo-3-iodobenzene Further, it is involved in the preparation of oxygen-tethered 1,6-enynes.

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

In 2019,ACS Catalysis included an article by Luo, Weiwei; Sun, Zhicheng; Fernando, E. H. Nisala; Nesterov, Vladimir N.; Cundari, Thomas R.; Wang, Hong. Application of 1774-47-6. The article was titled 《Asymmetric Ring-Opening of Donor-Acceptor Cyclopropanes with Primary Arylamines Catalyzed by a Chiral Heterobimetallic Catalyst》. The information in the text is summarized as follows:

An efficient catalytic asym. ring-opening reaction of donor-acceptor cyclopropanes with primary arylamines was developed. The reaction was achieved through the utilization of a chiral heterobimetallic catalyst, delivering a variety of chiral γ-amino acid derivatives in up to 93% yield and 99% ee. Stereochem. experiments suggest a dominant role for kinetic resolution in this asym. process, which is supported by a computational study of the reaction coordinate. A class of chiral bimetallic Lewis acid catalysts formed through a ligand exchange/transmetalation process was introduced in this work. The sym. structure of the bimetallic catalyst, i.e., Yb(OTf)3-Yb[P]3, was confirmed with X-ray crystallog. In addition to this study using Trimethylsulfoxonium iodide, there are many other studies that have used Trimethylsulfoxonium iodide(cas: 1774-47-6Application of 1774-47-6) was used in this study.

Trimethylsulfoxonium iodide(cas: 1774-47-6) reacts with sodium hydride to prepare dimethyloxosulfonium methylide, which is used as a methylene-transfer reagent in synthetic chemistry. It is used to prepare ylide, which reacts with carbonyl compounds to get epoxides.Application of 1774-47-6

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

In 2019,Synthesis included an article by Sarie, Jerome C.; Neufeld, Jessica; Daniliuc, Constantin G.; Gilmour, Ryan. Safety of 1-Bromo-4-iodobenzene. The article was titled 《Willgerodt-Type Dichloro(aryl)-λ3-Iodanes: A Structural Study》. The information in the text is summarized as follows:

Crystallog. structural anal. of four electronically diverse Willgerodt-type reagents is disclosed together with a solution-phase NMR anal. These data reveal a plethora of intermol. non-covalent interactions and confirm the expected T-shape geometry of the reagents. In all cases the I-Cl bonds are orthogonal to the plane of the aryl ring. This study provides important structural insights into this venerable class of dichlorination reagent and has implications for crystal engineering. After reading the article, we found that the author used 1-Bromo-4-iodobenzene(cas: 589-87-7Safety of 1-Bromo-4-iodobenzene)

1-Bromo-4-iodobenzene(cas: 589-87-7) has been employed as reagent for in situ desilylation and coupling of silylated alkynes, as starting reagent in the total syntheses of ent-conduramine A and ent-7-deoxypancratistatin (alkaloids), as substrate in copper-free Sonogashira coupling in aqueous acetone in synthesis of β,β,dibromostyrenesSafety of 1-Bromo-4-iodobenzene

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

The author of 《One-step synthesis of self-supported Ni3S2/NiS composite film on Ni foam by electrodeposition for high-performance supercapacitors》 were Huang, Haifu; Deng, Xiaoli; Yan, Liqing; Wei, Geng; Zhou, Wenzheng; Liang, Xianqing; Guo, Jin. And the article was published in Nanomaterials in 2019. SDS of cas: 516-12-1 The author mentioned the following in the article:

Herein, a facile one-step electrodeposition route was presented for preparing Ni3S2/NiS composite film on Ni foam substrate (denoted as NiSx/NF). The NiSx granular film is composed of mangy interconnected ultra-thin NiSx nanoflakes with porous structures. When applied as electrodes for supercapacitors, the ultra-thin nanoflakes can provide more active sites for redox reaction, and the interconnected porous structure has an advantage for electrolyte ions to penetrate into the inner space of active materials quickly. As expected, the obtained NiSx/NF sample exhibited high gravimetric capacitance of 1649.8 F·g-1 and areal capacitance of 2.63 F·cm-1. Furthermore, a gravimetric capacitance of 1120.1 F·g-1 can be maintained at a high c.d. of 20 mA·cm-1, suggesting a good rate capability. The influence of the different molar ratios of electrodeposition electrolyte (NiNO3 and thiourea) on the morphol. and electrochem. properties of NiSx/NF sample was investigated to provide an optimum route for one-step electrodeposition of Ni3S2/NiS composite film. The outstanding performance indicated the Ni3S2/NiS composite film on Ni foam has great potential as an electrode material for supercapacitors. In the experiment, the researchers used 1-Iodopyrrolidine-2,5-dione(cas: 516-12-1SDS of cas: 516-12-1)

1-Iodopyrrolidine-2,5-dione(cas: 516-12-1) is used in the preparation of vinyl sulfones from olefins and benzenesulfinic acid. It acts as a source for I+ and involved in Hunsdiecker reactions for the conversion of cinnamic acids, and propiolic acids to the corresponding alfa-halostyrenes and 1-halo-1-alkynes respectively. SDS of cas: 516-12-1

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

The author of 《Palladium-Catalyzed β-C-H Arylation of Aliphatic Aldehydes and Ketones Using Amino Amide as a Transient Directing Group》 were Dong, Cong; Wu, Liangfei; Yao, Jianwei; Wei, Kun. And the article was published in Organic Letters in 2019. Reference of 1-Iodo-4-methylbenzene The author mentioned the following in the article:

This paper describes a new amino-amide-based transient directing group (TDG). The TDG can exhibit better performance in the Pd-catalyzed arylation of aliphatic aldehydes and ketones. This reaction showed good substrate compatibility and regioselectivity. The results indicated that 3-amino-N-isopropylpropionamide was more beneficial to the β-arylation of aliphatic aldehydes than other TDGs under relatively mild conditions.1-Iodo-4-methylbenzene(cas: 624-31-7Reference of 1-Iodo-4-methylbenzene) was used in this study.

1-Iodo-4-methylbenzene(cas: 624-31-7) is used in wide range of medicals industrial applications as well as in pharmaceutical intermediates, polarizing films for Liquid Crystal Display (LCD) chemicals.Reference of 1-Iodo-4-methylbenzene

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

《Mechanistic Insights for Aniline-Catalyzed Halogenation Reactions》 was published in ChemCatChem in 2020. These research results belong to Qu, Zheng-Wang; Zhu, Hui; Grimme, Stefan. Related Products of 516-12-1 The article mentions the following:

Lewis base catalyzed electrophilic aromatic halogenation using N-halosuccinimides (NsX; X=Cl, Br, I) under mild conditions has attracted much attention, but the detailed mechanism remains elusive. Using the aniline MesNH2 and anisole PhOMe as the typical base catalyst and aromatic substrate, resp., a novel mechanism is revealed by extensive DFT calculations The autogenic protonation of imine XMes=NH (via Mes=NH+ mediated dimerization of MesNH2) is crucial to initialize the electrophilic halonium X+ transfer to nucleophilic substrates. It is shown that the aniline MesNH2 and more basic imine XMes=NH may act as efficient halonium X+ and proton H+ shuttles, resp., connected by the arenium XMesNH2+. Non-coordinating MesNH3+ salts are suggested as efficient catalyst for electrophilic iodination. Without suitable stabilization of the highly basic anion Ns-, the generally accepted concept of Lewis base catalyst as simple X+ shuttle will never work efficiently due to a high thermodn. barrier. In general, autogenic or addnl. acid additives should be used for more efficient Lewis base catalyzed halogenation. In the experiment, the researchers used many compounds, for example, 1-Iodopyrrolidine-2,5-dione(cas: 516-12-1Related Products of 516-12-1)

1-Iodopyrrolidine-2,5-dione(cas: 516-12-1) is used in the preparation of vinyl sulfones from olefins and benzenesulfinic acid. It acts as a source for I+ and involved in Hunsdiecker reactions for the conversion of cinnamic acids, and propiolic acids to the corresponding alfa-halostyrenes and 1-halo-1-alkynes respectively. Related Products of 516-12-1

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

《Metal-Free Chemoselective Reaction of Sulfoxonium Ylides and Thiosulfonates: Diverse Synthesis of 1,4-Diketones, Aryl Sulfursulfoxonium Ylides, and β-Keto Thiosulfones Derivatives》 was published in Organic Letters in 2020. These research results belong to Wang, Fei; Liu, Bo-Xi; Rao, Weidong; Wang, Shun-Yi. Computed Properties of C3H9IOS The article mentions the following:

A diverse chemoselective insertion reaction of sulfoxonium ylides and thiosulfonates under transition-metal-free conditions is developed, which successfully affords 1,4-diketone compounds, arylthiosulfoxide-ylides, and β-keto thiosulfones, resp. The nucleophilic addition of two mol. sulfoxonium ylides to construct sulfone-substituted 1,4-dione compounds is the highlight of this work. In the experiment, the researchers used many compounds, for example, Trimethylsulfoxonium iodide(cas: 1774-47-6Computed Properties of C3H9IOS)

Trimethylsulfoxonium iodide(cas: 1774-47-6) is a sulfoxonium salt. It is used to generate dimethyloxosulfonium methylide by reaction with sodium hydride. The latter compound is used as a methylene-transfer reagent, and is used to prepare epoxides.Computed Properties of C3H9IOS

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

《A new approach to large scale production of dimethyl sulfone: a promising and strong recyclable solvent for ligand-free Cu-catalyzed C-C cross-coupling reactions》 was published in Green Chemistry in 2020. These research results belong to Cheng, Shen; Wei, Wei; Zhang, Xingyu; Yu, Hewei; Huang, Mingming; Kazemnejadi, Milad. Name: 1-Iodonaphthalene The article mentions the following:

Di-Me sulfone (DMSN) was easily prepared through efficient oxidation of DMSO (DMSO) and used as a strong and green solvent for organic reactions. A mixture of HNO3/NaOCl was used as an oxidizing agent for efficient oxidation of DMSO to DMSN. The effect of DMSN was evaluated for copper-catalyzed coupling reactions. It is worth noting that DMSN could play the role of a ligand for copper ions. A general survey was accomplished for various types of C-C cross-coupling reactions catalyzed by CuI in DMSN in the absence of any ligand. Moderate to good yields were achieved for Sonogashira, Heck, and Suzuki cross-coupling reactions. Finally, DMSN was recovered and reused for several consecutive runs without any loss of its activity. The experimental process involved the reaction of 1-Iodonaphthalene(cas: 90-14-2Name: 1-Iodonaphthalene)

1-Iodonaphthalene(cas: 90-14-2) is one of organic iodides. Alkyl iodides react at a faster rate than alkyl fluorides due to the weak C-I bond. Iodo alkanes participate in a variety of organic synthesis reactions, which include the Simmons–Smith reaction (cyclopropanation using iodomethane), Williamson ether synthesis, Wittig reaction, Grignard reaction, alkyl coupling reactions, and Wurtz reaction.Name: 1-Iodonaphthalene

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

《Concise synthesis of a tetrasaccharide related to the repeating unit of the cell wall O-antigen of Salmonella enterica O60》 was written by Gucchait, Arin; Shit, Pradip; Misra, Anup Kumar. Recommanded Product: 1-Iodopyrrolidine-2,5-dione And the article was included in Tetrahedron in 2020. The article conveys some information:

Synthesis of a tetrasaccharide related to the repeating unit of the cell wall O-antigen of Salmonella enterica O60 has been achieved by sequential glycosylations in very good yield. Use of p-methoxybenzyl group (PMB) as an in situ removable protecting group allowed obtaining the desired compound in less number of steps. Synthesis of a beta-D-mannosidic linkage present in the mol. has been successfully achieved using D-mannosyl thioglycoside donor having a p-methoxybenzyl (PMB) group at remote C-3 position. A combination of N-iodosuccinimide (NIS) and perchloric acid supported over silica (HClO4-SiO2) has been used as thiophilic glycosylation promoter in glycosylation reactions. Thioglycoside of 3-amino-3-deoxy-D-fucose has been prepared and used in the synthetic scheme for its incorporation in α-glycosidic linkage. In the experiment, the researchers used 1-Iodopyrrolidine-2,5-dione(cas: 516-12-1Recommanded Product: 1-Iodopyrrolidine-2,5-dione)

1-Iodopyrrolidine-2,5-dione(cas: 516-12-1) is used in the preparation of vinyl sulfones from olefins and benzenesulfinic acid. It acts as a source for I+ and involved in Hunsdiecker reactions for the conversion of cinnamic acids, and propiolic acids to the corresponding alfa-halostyrenes and 1-halo-1-alkynes respectively. Recommanded Product: 1-Iodopyrrolidine-2,5-dione

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Meng, Qi; Zhang, Lian; Zhu, Xinhui; Teng, Qiaoqiao published their research in ChemistrySelect in 2021. The article was titled 《Synthesis of 9-O-Arylated Berberine with a Polystyrene Resin Supported Copper(II) Catalyst》.Safety of 4-Iodopyridine The article contains the following contents:

A series of polyfluorobenzene, pyridine and aniline substituted berberine derivatives I (Ar = Ph, 4-H2NC6H4, 3-pyridyl, etc.) were prepared via resin-supported Cu(II) catalyzed cross-coupling reactions of tetrahydroberberrubine with iodoarenes and subsequent I2 oxidation The best catalyst, a polyethyleneimine functionalized polystyrene supported Cu2+ (PSAPA·Cu(II)), could be reused for at least 5 runs without significant loss of catalytic activity. Comparative studies on the morphol. and porous structures of the materials suggested a catalyst with a moderate sp. surface area and larger pore diameters was more active in catalyzing the cross-coupling reactions.4-Iodopyridine(cas: 15854-87-2Safety of 4-Iodopyridine) was used in this study.

4-Iodopyridine(cas: 15854-87-2) belongs to pyridine. In industry and in the lab, pyridine is used as a reaction solvent, particularly when its basicity is useful, and as a starting material for synthesizing some herbicides, fungicides, and antiseptics.Safety of 4-Iodopyridine

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com