Author: Jessica.F

《Zinc (II) complex immobilized on the surface of magnetic nanoparticles modified with phenanthroline: A novel and efficient nanomagnetic reusable catalyst for cross-coupling reaction of aryl iodides with terminal aromatic alkynes》 was written by Raya, Indah; Abdalkareem Jasim, Saade; Hashim Abdulkadhim, Adnan; Hashem Abbud, Luay; Sharma, Himanshu. SDS of cas: 15854-87-2This research focused onzinc magnetic nanoparticle catalyst Sonogashira crosscoupling catalyst aryliodide arylalkyne. The article conveys some information:

A novel and green nanomagnetic Zn catalyst were fabricated via the immobilization of Zn (II) complex on the surface of magnetic nanoparticles modified with phenanthroline (MNPs-Phen-Zn(II)). The structure of MNPs-Phen-Zn(II) nanomaterial was characterized by spectroscopic techniques including FTIR spectroscopy, SEM, TEM, EDX, XRD, VSM, and ICP-OES. The resulting Zn nanomagnetic catalyst was shown high catalytic activity for the synthesis of disubstituted alkynes via C(sp2)-C(sp) cross-coupling reactions of alkynes with aryl iodides under eco-friendly conditions. It is the first report on the use of Zn nanomagnetic catalyst for the Sonogashira type cross-coupling reaction of alkynes with aryl iodides in the absence of added Pd and Cu sources. The simple preparation of the catalyst from com. available materials, excellent chemoselectivity, easy separation of products, and straightforward recovery and reusability of the catalyst with unaltered activity make the procedure a green and practical method. The results came from multiple reactions, including the reaction of 4-Iodopyridine(cas: 15854-87-2SDS of cas: 15854-87-2)

4-Iodopyridine(cas: 15854-87-2) is a halogenated heterocycle that is a building block for proteomics research. 4-Iodopyridine is used as a reagent in the synthesis of indazolylamides as glucocorticoid receptor agonists.SDS of cas: 15854-87-2

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Related Products of 41252-95-3On September 30, 2009 ,《Synthesis of 6-substituted imidazo[2,1-b]thiazoles via Pd/Cu-mediated Sonogashira coupling in water》 was published in Tetrahedron Letters. The article was written by Kamali, Taghi A.; Bakherad, Mohammad; Nasrollahzadeh, Mahmoud; Farhangi, Shiva; Habibi, Davood. The article contains the following contents:

The reaction of 2-amino-3-(2-propynyl)thiazolium bromide with various iodobenzenes, catalyzed by Pd/Cu, in the presence of sodium lauryl sulfate as surfactant and Cs2CO3 as base, in water, leads to the formation of 6-substituted imidazo[2,1-b]thiazoles. In the experiment, the researchers used 1-Chloro-4-iodo-2-nitrobenzene(cas: 41252-95-3Related Products of 41252-95-3)

1-Chloro-4-iodo-2-nitrobenzene(cas: 41252-95-3) belongs to organic iodides. Alkyl iodides react at a faster rate than alkyl fluorides due to the weak C-I bond.Iodo alkanes participate in a variety of organic synthesis reactions, which include the Simmons–Smith reaction (cyclopropanation using iodomethane), Williamson ether synthesis, Wittig reaction, Grignard reaction, alkyl coupling reactions, and Wurtz reaction.Related Products of 41252-95-3

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

In 2019,Journal of Organic Chemistry included an article by Niu, Yi-Jie; Sui, Guo-Hui; Zheng, Hong-Xing; Shan, Xiang-Huan; Tie, Lin; Fu, Jia-Le; Qu, Jian-Ping; Kang, Yan-Biao. Related Products of 90-14-2. The article was titled 《Competing Dehalogenation versus Borylation of Aryl Iodides and Bromides under Transition-Metal-Free Basic Conditions》. The information in the text is summarized as follows:

Selectivity-controllable base-promoted transition-metal-free borylation and dehalogenation of aryl halides are described. Under the conditions of borylation, the dehalogenation which emerges as a competitive side reaction was well-controlled by carefully controlling the borylation conditions. However, the dehalogenation using benzaldehyde as a H source also was accomplished. The applications of direct radical borylation and dehalogenation of aryl halides demonstrate their synthetic practicability in pharmaceutical-oriented organic synthesis. Based on the exptl. evidences, the tBuOK/1,10-Phen-triggered radical nature of both competitive reactions was revealed. In the experiment, the researchers used 1-Iodonaphthalene(cas: 90-14-2Related Products of 90-14-2)

1-Iodonaphthalene(cas: 90-14-2) is one of organic iodides. Organic iodides are used in veterinary products (Organic Iodide Powder) as a nutritional source of iodine. In the chemical industry, alkyl iodides serve as excellent alkylating agents and, specifically, methyl iodide is used as a methylating agent in the synthesis of various pharmaceutical drugs. Oceanic alkyl iodides are believed to be the principal source of atmospheric iodine.Related Products of 90-14-2

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

In 2019,Organic Letters included an article by Tukhtaev, Hamidulla B.; Ivanov, Konstantin L.; Bezzubov, Stanislav I.; Cheshkov, Dmitry A.; Melnikov, Mikhail Ya.; Budynina, Ekaterina M.. Computed Properties of C3H9IOS. The article was titled 《aza-Wittig Reaction with Nitriles: How Carbonyl Function Switches from Reacting to Activating》. The information in the text is summarized as follows:

Transformations of α-EWG-substituted (electron-withdrawing group, EWG) γ-azidobutyronitriles proceeding via unusual aza-Wittig reactions between the phosphazene and nitrile functions and affording pyrrole-derived iminophosphazenes were developed. α-EWGs were found to control chemoselectivity and, depending on their nature, act as CN group activators (e.g., ester, amide, or nitrile) or competitors (e.g., ketone) in aza-Wittig reactions. To demonstrate the synthetic utility of the obtained iminophosphazenes as N,N-binucleophiles, their transformations into pyrrole-fused systems, pyrrolo[1,2-a]imidazoles and pyrrolo[1,2-a][1,3]diazepines, were carried out. The experimental process involved the reaction of Trimethylsulfoxonium iodide(cas: 1774-47-6Computed Properties of C3H9IOS)

Trimethylsulfoxonium iodide(cas: 1774-47-6) is a sulfoxonium salt. It is used to generate dimethyloxosulfonium methylide by reaction with sodium hydride. The latter compound is used as a methylene-transfer reagent, and is used to prepare epoxides.Computed Properties of C3H9IOS

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

The author of 《A Mild and Regioselective Synthesis of α-Fluoroketones via Gold and Selectfluor Partnership》 were Chen, Xi; Martini, Sophie; Michelet, Veronique. And the article was published in Advanced Synthesis & Catalysis in 2019. Computed Properties of C6H4BrI The author mentioned the following in the article:

Alkynylaryl aldehydes and Me ketones such as I underwent regioselective fluorohydroxylation with Selectfluor in aqueous EtOH in the presence of Ph3PAuCl at ambient temperature to yield α-fluoro ketones such as II. The mechanism of the reaction was studied by the (lack of) reaction of diphenylacetylene and by deuterium labeling and intermediate studies. Selected fluoroketone, including II, were converted to 3-substituted 4-fluoroisoquinolines such as III. In the experiment, the researchers used many compounds, for example, 1-Bromo-3-iodobenzene(cas: 591-18-4Computed Properties of C6H4BrI)

1-Bromo-3-iodobenzene(cas: 591-18-4) has been used in the preparation of 1-(3′-bromophenyl)-3,3,4,4,5,5,6,6,7,7,8,8,9,9,10,10,10-heptadecafluorodec-1-ene and 1-(3′-bromophenyl)-3,3,4,4,5,5,6,6,7,7,8,8,8-tridecafluorooct-1-ene.Computed Properties of C6H4BrI

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

The author of 《Mechanism of Hypervalent Iodine Promoted Fluorocyclization of Unsaturated Alcohols: Metathesis via Double Acids Activation》 were Shu, Siwei; Li, Yinwu; Jiang, Jingxing; Ke, Zhuofeng; Liu, Yan. And the article was published in Journal of Organic Chemistry in 2019. Product Details of 624-31-7 The author mentioned the following in the article:

Lewis/Bronsted acid activation plays a key role in hypervalent iodine reagent-mediated reactions. In addition to generally accepted cis-activation or trans-activation, this study reveals another important Lewis/Bronsted acid activation mode, the double-activation. Different from the generally proposed iodine(III)iranium SN2 mechanism, the hypervalent difluoro-iodoarene-promoted fluorocyclization of unsaturated alc. prefers to undergo the metathesis mechanism via an iodine(III)-π intermediate. The results came from multiple reactions, including the reaction of 1-Iodo-4-methylbenzene(cas: 624-31-7Product Details of 624-31-7)

1-Iodo-4-methylbenzene(cas: 624-31-7) is used in wide range of medicals industrial applications as well as in pharmaceutical intermediates, polarizing films for Liquid Crystal Display (LCD) chemicals.Product Details of 624-31-7

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

The author of 《Microwave-Assisted Synthesis of Core-Crosslinked Star Polymers with Benzophenone Derivatives in the Core》 were Kang, Tae-Hyeon; Lee, Hyung-il. And the article was published in Macromolecular Research in 2019. Recommanded Product: 4-Iodobenzoic acid The author mentioned the following in the article:

Core-crosslinked star polymers, which have polyethylene oxide (PEO) as a shell and cross-linked poly(2-{4′-iodobenzoyloxy}-Et methacrylate) (PIEMA) with benzophenone derivatives as a core, have been successfully synthesized by an “”arm-first”” method. PEO-b-PIEMA was prepared via atom transfer radical polymerization (ATRP) of 2-{4′-iodobenzoyloxy}-Et methacrylate (4-IEMA) with preformed PEO-Br as a macroinitiator. Core-crosslinked star polymers (CCSP) were efficiently synthesized by ultrafast carbonylation reactions under air by flash microwave irradiation in the presence of dicobalt octacarbonyl in 6 min. Gel permeation chromatog. (GPC) trace of CCSP showed a drastic shift to a higher mol. weight when compared to precursor polymer, PEO-b-PIEMA diblock copolymer, indicating that the carbonylation reaction was fully progressed. The CCSP with benzophenone was successfully immobilized on a silicon wafer through a photochem. reaction under UV irradiation The results came from multiple reactions, including the reaction of 4-Iodobenzoic acid(cas: 619-58-9Recommanded Product: 4-Iodobenzoic acid)

4-Iodobenzoic acid(cas: 619-58-9) belongs to organic iodides.Recommanded Product: 4-Iodobenzoic acid The carbon-iodine bond is weaker than other carbon-halogen bonds due to the poor electronegative nature of the iodine atom. In general, organic iodides are light-sensitive and turn yellow during storage, owing to the formation of iodine.

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

The author of 《Anode interfacial layer formation via reductive ethyl detaching of organic iodide in lithium-oxygen batteries》 were Zhang, Xiao-Ping; Sun, Yi-Yang; Sun, Zhuang; Yang, Chu-Shu; Zhang, Tao. And the article was published in Nature Communications in 2019. Electric Literature of C3H9IOS The author mentioned the following in the article:

As soluble catalysts, redox mediators can reduce the high charging overpotential of lithium-oxygen batteries by providing sufficient liquid-solid interface for lithium peroxide decomposition However, the redox mediators usually introduce undesirable reactions. In particular, the so-called “”shuttle effect”” leads to the loss of both the redox mediators and elec. energy efficiency. In this study, an organic compound, triethylsulfonium iodide, is found to act bifunctionally as both a redox mediator and a solid electrolyte interphase-forming agent for lithium-oxygen batteries. During charging, the organic iodide exhibits comparable lithium peroxide-oxidizing capability with inorganic iodides. Meanwhile, it in situ generates an interfacial layer on lithium anode via reductive Et detaching and the subsequent oxidation This layer prevents the lithium anode from reacting with the redox mediators and allows efficient lithium-ion transfer leading to dendrite-free lithium anode. Significantly improved cycling performance has been achieved by the bifunctional organic iodide redox mediator. In the part of experimental materials, we found many familiar compounds, such as Trimethylsulfoxonium iodide(cas: 1774-47-6Electric Literature of C3H9IOS)

Trimethylsulfoxonium iodide(cas: 1774-47-6) reacts with sodium hydride to prepare dimethyloxosulfonium methylide, which is used as a methylene-transfer reagent in synthetic chemistry. It is used to prepare ylide, which reacts with carbonyl compounds to get epoxides. Further, it reacts with alfa,beta-unsaturated esters to get cyclopropyl esters.Electric Literature of C3H9IOS

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

The author of 《Pd nanocatalyst adorning coral reef nanocomposite for the synthesis of nitriles: utility of Cucurbita pepo leaf extract as a stabilizing and reducing agent》 were Nasrollahzadeh, Mahmoud; Ghorbannezhad, Fatemeh; Sajadi, S. Mohammad; Varma, Rajender S.. And the article was published in Nanomaterials in 2019. Formula: C5H4IN The author mentioned the following in the article:

A simple procedure for the palladium-catalyzed cyanation of aryl halides is described via a nucleophilic non-toxic cyanide source, K4[Fe(CN)6] in the presence of Pd/coral reef nanocomposite as a heterogeneous catalyst; the protocol provides a useful and easy method for the synthesis of aryl nitriles that are generated from the corresponding variant aryl halides, with sodium carbonate as a base. The nanocatalyst was prepared by a biol. process using aqueous extract of leaves of Cucurbita pepo as a stabilizing and reducing agent and coral reef as a natural support, without deploying any hazardous chems. The catalyst, that is easily separable from the reaction mixture and reused multiple times, was characterized by FT-IR (Fourier-Transform IR Spectroscopy), ICP-AES (Inductively Coupled Plasma Atomic Emission Spectroscopy), XRD (X-ray Diffraction), TEM (Transmission Electron Microscopy), FE-SEM (Field Emission SEM), EDS (Energy Dispersive X-ray Spectroscopy) and elemental mapping. In the part of experimental materials, we found many familiar compounds, such as 4-Iodopyridine(cas: 15854-87-2Formula: C5H4IN)

4-Iodopyridine(cas: 15854-87-2) is used as a reagent in the synthesis of indazolylamides as glucocorticoid receptor agonists. 4-Iodopyridine is a halogenated heterocycle that is a building block for proteomics research.Formula: C5H4IN

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

《Ortho C-H arylation of arenes at room temperature using visible light ruthenium C-H activation》 was published in Chemical Science in 2020. These research results belong to Sagadevan, Arunachalam; Charitou, Anastasios; Wang, Fen; Ivanova, Maria; Vuagnat, Martin; Greaney, Michael F.. Application In Synthesis of 1-Bromo-4-iodobenzene The article mentions the following:

A ruthenium-catalyzed ortho C-H arylation process is described using visible light. Using the readily available catalyst [RuCl2(p-cymene)]2, visible light irradiation was found to enable arylation of 2-aryl-pyridines I (R1 = 4-methoxyphenyl, naphthalen-2-yl, thiophen-2-yl, etc.; R2 = H, 2-Me, 4-Me, 5-Me) at room temperature for a range of aryl halides R3X (R3 = 2-methoxyphenyl, 4-phenylphenyl, thiophen-2-yl, etc.; X = I, Br). In the experimental materials used by the author, we found 1-Bromo-4-iodobenzene(cas: 589-87-7Application In Synthesis of 1-Bromo-4-iodobenzene)

1-Bromo-4-iodobenzene(cas: 589-87-7) has been employed as reagent for in situ desilylation and coupling of silylated alkynes, as starting reagent in the total syntheses of ent-conduramine A and ent-7-deoxypancratistatin (alkaloids), as substrate in copper-free Sonogashira coupling in aqueous acetone in synthesis of β,β,dibromostyrenesApplication In Synthesis of 1-Bromo-4-iodobenzene

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com