In 2018,Wangoli, Panyako Asman; Kinunda, Grace published 《The effect of alkyl chain tethers on the kinetics and mechanistic behaviour of bifunctional dinuclear platinum(II) complexes bearing N,N’-dipyridylamine ligands》.New Journal of Chemistry published the findings.Reference of 1,2-Diiodoethane The information in the text is summarized as follows:
In the current paper, the authors report the kinetics of bifunctional dinuclear Pt(II) complexes, viz., {1,2-bis(di-2-pyridylamino)alkane}tetraaquadiplatinum(II), alkane = (CH2)2 (PtL2), (CH2)3 (PtL3), (CH2)4 (PtL4), (CH2)5 (PtL5) and (CH2)6 (PtL6). The substitution reactions were carried out on tetraaqua complexes with thiourea nucleophiles under pseudo-first-order conditions as a function of nucleophile concentration and temperature by stopped-flow and UV-visible spectrophotometric techniques. An exptl. study was conducted with the aim of determining the influence of alkyl chains on the steric and electronic structure of dinuclear Pt(II) complexes. The reactivity of these complexes was dependent on the length of the alkylene spacer. The results obtained herein demonstrate the intriguing odd-even effects induced by the alkyl chain on the complexes. Artificial constraints imposed by the alkyl chain significantly affect their conformational structure to be either synperiplanar (syn-) or antiperiplanar (anti-) characterized by the odd and even effect. The kinetic, mechanistic and conformational behavior was influenced by the size of the alkyl chain in accordance with odd-even alterations of the spacer. Computational modeling using d. functional theory (DFT) calculations supplemented exptl. findings that structural features and the reactivity pattern of these metal complexes are governed by both steric and electronic effects arising from the flexibility and inductive nature of the alkyl spacer. The strong σ-donicity of longer alkyl chains favors sufficient accumulation of electron d. at the metal center and stabilizes a 14-electron intermediate. The study shows the HOMO-LUMO energy (ΔE) is affected by the length of the spacer. Kinetic and DFT data indicate electron donation by the alkyl spacer. The low pos. values of enthalpy of activation and significantly large neg. values of entropy of activation indicate an associative mechanism of substitution. The experimental part of the paper was very detailed, including the reaction process of 1,2-Diiodoethane(cas: 624-73-7Reference of 1,2-Diiodoethane)
1,2-Diiodoethane(cas: 624-73-7) is one of organic iodides. Alkyl iodides react at a faster rate than alkyl fluorides due to the weak C-I bond. Iodo alkanes participate in a variety of organic synthesis reactions, which include the SimmonsSmith reaction (cyclopropanation using iodomethane), Williamson ether synthesis, Wittig reaction, Grignard reaction, alkyl coupling reactions, and Wurtz reaction.Reference of 1,2-Diiodoethane
Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com