Author: Jessica.F

Bakherad, Mohammad; Bahramian, Bahram; Nasr-Isfahani, Hossein; Keivanloo, Ali; Sang, Golnaz published an article on February 28 ,2009. The article was titled 《Polystyrene-supported palladium(II) ethylenediamine complex: A recyclable catalyst for the syntheses of 2-benzylimidazo[2,1-b][1,3]benzothiazoles by Sonogashira reaction》, and you may find the article in Chinese Journal of Chemistry.Recommanded Product: 41252-95-3 The information in the text is summarized as follows:

The polymer-supported palladium(II) ethylenediamine complex was used as a catalyst for the heterocyclization by Sonogashira reaction between aryl iodides and 2-amino-3-(2-propynyl)-1,3-benzothiazolium bromide and could readily be recovered from the reaction medium by a simple filtration and reused without a significant loss in its activity. In addition to this study using 1-Chloro-4-iodo-2-nitrobenzene, there are many other studies that have used 1-Chloro-4-iodo-2-nitrobenzene(cas: 41252-95-3Recommanded Product: 41252-95-3) was used in this study.

1-Chloro-4-iodo-2-nitrobenzene(cas: 41252-95-3) belongs to organic iodides. Generally organic iodides can be divided into two classes of alkyl iodides and aryl iodides. Typical reactions of alkyl iodides include nucleophilic substitution, elimination, reduction, and the formation of organometallics.Recommanded Product: 41252-95-3Halogenation of aromatic hydrocarbons is a very important reaction via an electrophilic aromatic substitution.

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Bakherad, Mohammad; Keivanloo, Ali; Mohammadi, Marzieh; Jajarmi, Saeideh published an article in Letters in Organic Chemistry. The title of the article was 《Syntheses of 2-benzyl substituted imidazo[1,2-a]pyrimidines via coupling-cyclization under Pd-Cu catalysis》.Product Details of 41252-95-3 The author mentioned the following in the article:

The reaction of 1-(prop-2-yn-1-yl)pyrimidin-2(1H)-imine with various halobenzenes in the presence of a palladium catalyst leads to the production of 2-benzyl substituted imidazo[1,2-a]pyrimidines, e.g. I (R = 4-O2N, 2-O2N-4-Cl, 4-MeCO).1-Chloro-4-iodo-2-nitrobenzene(cas: 41252-95-3Product Details of 41252-95-3) was used in this study.

1-Chloro-4-iodo-2-nitrobenzene(cas: 41252-95-3) belongs to organic iodides. The carbon-iodine bond is weaker than other carbon-halogen bonds due to the poor electronegative nature of the iodine atom. Organic iodides can be alkyl, alkenyl, or alkynyl, and all of them are very reactive toward with many kinds of nucleophiles.Product Details of 41252-95-3

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

In 2017,Lu, Xi; Wang, Yan; Zhang, Ben; Pi, Jing-Jing; Wang, Xiao-Xu; Gong, Tian-Jun; Xiao, Bin; Fu, Yao published 《Nickel-Catalyzed Defluorinative Reductive Cross-Coupling of gem-Difluoroalkenes with Unactivated Secondary and Tertiary Alkyl Halides》.Journal of the American Chemical Society published the findings.COA of Formula: C10H18INO2 The information in the text is summarized as follows:

In the presence of Ni(cod)2 and an imidazolinylpyridine ligand, 1,1-difluoroalkenes such as I underwent chemoselective and diastereoselective reductive defluorinative coupling reactions with secondary alkyl bromides and iodides such as iodocyclohexane mediated by bis(pinacolato)diboron and tripotassium phosphate to yield (Z)-arylfluoroalkenes such as II in 36-95% yields and in 8:1->50:1 Z:E diastereoselectivities; the reaction was also used to couple difluoroalkenes with primary alkyl iodides and 1,1-difluoroalkyl bromides using a catalyst generated from NiBr2(diglyme) and 4,7-dimethoxy-1,10-phenanthroline. In the experimental materials used by the author, we found tert-Butyl 4-iodopiperidine-1-carboxylate(cas: 301673-14-3COA of Formula: C10H18INO2)

tert-Butyl 4-iodopiperidine-1-carboxylate(cas: 301673-14-3) is one of organic iodides. Organic iodides are used in veterinary products (Organic Iodide Powder) as a nutritional source of iodine. In the chemical industry, alkyl iodides serve as excellent alkylating agents and, specifically, methyl iodide is used as a methylating agent in the synthesis of various pharmaceutical drugs. Oceanic alkyl iodides are believed to be the principal source of atmospheric iodine.COA of Formula: C10H18INO2

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

In 2017,Bogomolov, Alexandr S.; Goldort, Veniamin G.; Kochubei, Sergei A.; Baklanov, Alexey V. published 《Photodissociation of van der Waals complexes of iodine X-I2 (X = I2, C2H4) via charge-transfer state: velocity map imaging investigation》.Journal of Chemical Physics published the findings.Application of 624-73-7 The information in the text is summarized as follows:

The photodissociation of van der Waals complexes of iodine X-I2 (X = I2, C2H4) excited via Charge-Transfer (CT) band has been studied with the velocity map imaging technique. Photodissociation of both complexes gives rise to translationally “”hot”” mol. iodine I2 via channels differing by kinetic energy and angular distribution of the recoil directions. These measured characteristics together with the anal. of the model potential energy surface for these complexes allow us to infer the back-electron-transfer (BET) in the CT state to be a source of observed photodissociation channels and to make conclusions on the location of conical intersections where the BET process takes place. The BET process is concluded to provide an I2 mol. in the electronic ground state with moderate vibrational excitation as well as X mol. in the electronic excited state. In the case of X = I2, the BET process converts anion I2- of the CT state into the neutral I2 in the repulsive excited electronic state which then dissociates promptly giving rise to a pair of I atoms in the fine states 2P1/2. In the case of C2H4-I2, the C2H4 mols. appear in the triplet T1 electronic state. Conical intersection for corresponding BET process becomes energetically accessible after partial twisting of C2H4+ frame in the excited CT state of complex. The C2H4(T)-I2 complex gives rise to triplet ethylene as well as singlet ethylene via the T-S conversion. (c) 2017 American Institute of Physics. After reading the article, we found that the author used 1,2-Diiodoethane(cas: 624-73-7Application of 624-73-7)

1,2-Diiodoethane(cas: 624-73-7) is one of organic iodides. The carbon-iodine bond is weaker than other carbon-halogen bonds due to the poor electronegative nature of the iodine atom. In general, organic iodides are light-sensitive and turn yellow during storage, owing to the formation of iodine. Organic iodides can be alkyl, alkenyl, or alkynyl, and all of them are very reactive toward with many kinds of nucleophiles.Application of 624-73-7

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

In 2019,Journal of Organic Chemistry included an article by Wisniewski, Steven R.; Stevens, Jason M.; Yu, Miao; Fraunhoffer, Kenneth J.; Romero, Evan O.; Savage, Scott A.. SDS of cas: 591-18-4. The article was titled 《Utilizing Native Directing Groups: Synthesis of a Selective IKur Inhibitor, BMS-919373, via a Regioselective C-H Arylation》. The information in the text is summarized as follows:

BMS-919373 (I) is a highly functionalized quinazoline under investigation as a selective, potent Ikur current blocker. By utilizing the aminomethylpyridine side chain at C-4, a selective C-H functionalization at C-5 was invented, enabling the efficient synthesis of this mol. The strategy of leveraging this inherent directing group allowed the synthesis of this complex heterocycle in only six steps from commodity chems. The scope of the C-H activation was further investigated, and the generality of the transformation across a series of bicyclic aromatic heterocycles was explored. In the experiment, the researchers used many compounds, for example, 1-Bromo-3-iodobenzene(cas: 591-18-4SDS of cas: 591-18-4)

1-Bromo-3-iodobenzene(cas: 591-18-4) has been used in the preparation of 1-(3′-bromophenyl)-3,3,4,4,5,5,6,6,7,7,8,8,9,9,10,10,10-heptadecafluorodec-1-ene and 1-(3′-bromophenyl)-3,3,4,4,5,5,6,6,7,7,8,8,8-tridecafluorooct-1-ene.SDS of cas: 591-18-4 Further, it is involved in the preparation of oxygen-tethered 1,6-enynes.

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

In 2019,Journal of Organic Chemistry included an article by Wisniewski, Steven R.; Savage, Scott A.; Romero, Evan O.; Eastgate, Martin D.; Tan, Yichen; Simmons, Eric M.; Plata, R. Erik; Sowa, John R.; Blackmond, Donna G.. Related Products of 591-18-4. The article was titled 《Utilizing Native Directing Groups: Mechanistic Understanding of a Direct Arylation Leads to Formation of Tetracyclic Heterocycles via Tandem Intermolecular, Intramolecular C-H Activation》. The information in the text is summarized as follows:

A mechanistic study on a direct arylation using a native picolylamine directing group is reported. Kinetic studies determined the concentration dependence of substrates and catalysts, as well as catalyst degradation, which led to the development of a new set of reaction conditions capable of affording a robust kinetic profile. During reaction optimization, a small impurity was observed, which was determined to be a dual C-H activation product. A second set of conditions were found to flip the selectivity of the C-H activation to form this tetracycle in high yield. A catalytic cycle is proposed for the intermol./intramol. C-H activation pathway. The experimental part of the paper was very detailed, including the reaction process of 1-Bromo-3-iodobenzene(cas: 591-18-4Related Products of 591-18-4)

1-Bromo-3-iodobenzene(cas: 591-18-4) has been used in the preparation of 1-(3′-bromophenyl)-3,3,4,4,5,5,6,6,7,7,8,8,9,9,10,10,10-heptadecafluorodec-1-ene and 1-(3′-bromophenyl)-3,3,4,4,5,5,6,6,7,7,8,8,8-tridecafluorooct-1-ene.Related Products of 591-18-4 Further, it is involved in the preparation of oxygen-tethered 1,6-enynes.

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

The author of 《R-Benzylidenehydrazides of NH-Furoyl-5-Iodoanthranilic Acids: Synthesis, Properties, and Analgesic and Antibacterial Activity》 were Gazizova, A. F.; Kurbatov, E. R.; Makhmudov, R. R.; Bobyleva, A. A.; Korkodinova, L. M.; Kurbatova, A. A.. And the article was published in Pharmaceutical Chemistry Journal in 2019. Synthetic Route of C7H5IO The author mentioned the following in the article:

A series of R-benzylidenehydrazides of NH-furoyl-5-iodoanthranilic acid were synthesized by condensing NH-furoyl-5-iodoanthranilic acid hydrazide with aromatic aldehydes. Their structures were confirmed using IR and PMR spectroscopy. Their analgesic and antibacterial activities were studied. The results came from multiple reactions, including the reaction of 4-Iodobenzaldehyde(cas: 15164-44-0Synthetic Route of C7H5IO)

4-Iodobenzaldehyde(cas: 15164-44-0) is used in synthesis of 4-[2-(trimethylsilyl)ethynyl]benzaldehyde, 5,15-dimesityl-10-(3-[2-(trimethylsilyl)ethynyi]phenyl}-20-(4-iodophenyl)porphyrin, and 5,15-dimesityl-10-[3,5-bis{2-[4-(N,N’-difluoroboryl-1,9-dimethyidipyrrin-5-yl)-phenyl]ethynyl}phenyl]-20-(4-iodophenyl)porphyrin.Synthetic Route of C7H5IO

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

The author of 《Intestinal electrogenic sodium-dependent glucose absorption in tilapia and trout reveal species differences in SLC5A-associated kinetic segmental segregation》 were Subramaniam, Marina; Weber, Lynn P.; Loewen, Matthew E.. And the article was published in American Journal of Physiology in 2019. Safety of 1-Iodopyrrolidine-2,5-dione The author mentioned the following in the article:

Electrogenic sodium-dependent glucose transport along the length of the intestine was compared between the omnivorous Nile tilapia (Oreochromis niloticus) and the carnivorous rainbow trout (Oncorhynchus mykiss) in Ussing chambers. In tilapia, a high-affinity, high-capacity kinetic system accounted for the transport throughout the proximal intestine, midintestine, and hindgut segments. Similar dapagliflozin and phloridzin dihydrate inhibition across all segments support this homogenous high-affinity, high-capacity system throughout the tilapia intestine. Genomic and gene expression anal. supported findings by identifying 10 of the known 12 SLC5A family members, with homogeneous expression throughout the segments with dominant expression of sodium-glucose cotransporter 1 (SGLT1; SLC5A1) and sodium-myoinositol cotransporter 2 (SMIT2; SLC5A11). In contrast, trout’s electrogenic sodium-dependent glucose absorption was 20-35 times lower and segregated into three significantly different kinetic systems found in different anatomical segments: a high-affinity, low-capacity system in the pyloric ceca; a super-high-affinity, low-capacity system in the midgut; and a low-affinity, low-capacity system in the hindgut. Genomic and gene expression anal. found 5 of the known 12 SLC5A family members with dominant expression of SGLT1 (SLC5A1), sodium-glucose cotransporter 2 (SGLT2; SLC5A2), and SMIT2 (SLC5A11) in the pyloric ceca, and only SGLT1 (SLC5A1) in the midgut, accounting for differences in kinetics between the two. The hindgut presented a low-affinity, low-capacity system partially attributed to a decrease in SGLT1 (SLC5A1). Overall, the omnivorous tilapia had a higher electrogenic glucose absorption than the carnivorous trout, represented with different kinetic systems and a greater expression and number of SLC5A orthologs. Fish differ from mammals, having hindgut electrogenic glucose absorption and segment specific transport kinetics. The experimental part of the paper was very detailed, including the reaction process of 1-Iodopyrrolidine-2,5-dione(cas: 516-12-1Safety of 1-Iodopyrrolidine-2,5-dione)

1-Iodopyrrolidine-2,5-dione(cas: 516-12-1) is used in the preparation of vinyl sulfones from olefins and benzenesulfinic acid. It acts as a source for I+ and involved in Hunsdiecker reactions for the conversion of cinnamic acids, and propiolic acids to the corresponding alfa-halostyrenes and 1-halo-1-alkynes respectively. Safety of 1-Iodopyrrolidine-2,5-dione

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

The author of 《Pd@GO/Fe3O4/PAA/DCA: a novel magnetic heterogeneous catalyst for promoting the Sonogashira cross-coupling reaction》 were Daraie, Mansoureh; Heravi, Majid M.; Kazemi, Shaghayegh Sadat. And the article was published in Journal of Coordination Chemistry in 2019. Synthetic Route of C10H7I The author mentioned the following in the article:

A hybrid system involving graphene oxide (GO), magnetic oxide (Fe3O4), acrylamide and dicyandiamide was prepared via amine functionalization of GO/Fe3O4 by covalent bonding with acrylamide and subsequent reaction with dicyandiamide to provide a multinitrogen containing polymer on the surface of GO. This hybrid system was used as a heterogeneous catalyst support for immobilizing Pd nanoparticles to provide the hybrid, Pd@GO/Fe3O4/PAA/DCA. This nano-Pd composite was characterized using FTIR, TEM, SEM, vibrating sample magnetometer, TGA, x-ray diffraction, and ICP techniques and used for promoting Sonogashira cross-coupling under mild reaction conditions. This heterogeneous and magnetic catalyst was easily separated by external magnet and was reused in a model reaction, efficiently up to six times with slight loss of catalytic activity and Pd leaching, showing the suitability of GO/Fe3O4/PAA/DCA for embedding Pd nanoparticles. To check the effect of the number of surface nitrogens of the polymeric chain on the catalytic performance, the activity of the catalyst was compared with Pd@GO/Fe3O4/PAA; increased number of the surface nitrogens on the chain polymer leads to higher loading of Pd and lower the Pd leaching. In the experimental materials used by the author, we found 1-Iodonaphthalene(cas: 90-14-2Synthetic Route of C10H7I)

1-Iodonaphthalene(cas: 90-14-2) is one of organic iodides. The carbon-iodine bond is weaker than other carbon-halogen bonds due to the poor electronegative nature of the iodine atom. In general, organic iodides are light-sensitive and turn yellow during storage, owing to the formation of iodine. Organic iodides can be alkyl, alkenyl, or alkynyl, and all of them are very reactive toward with many kinds of nucleophiles.Synthetic Route of C10H7I

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

The author of 《Rational design of cyclopenta[2,1-b;3,4-b’]dithiophene-bridged hole transporting materials for highly efficient and stable perovskite solar cells》 were Lin, Yan-Duo; Lee, Kun-Mu; Ke, Bo-Yu; Chen, Kai-Shiang; Cheng, Hao-Chien; Lin, Wei-Juih; Chang, Sheng Hsiung; Wu, Chun-Guey; Kuo, Ming-Chung; Chung, Hsin-Cheng; Chou, Chien-Chun; Chen, Heng-Yu; Liau, Kang-Ling; Chow, Tahsin J.; Sun, Shih-Sheng. And the article was published in Energy Technology (Weinheim, Germany) in 2019. Quality Control of 1-Bromo-4-iodobenzene The author mentioned the following in the article:

A series of small-mol.-based hole-transporting materials (HTMs) featuring a 4H-cyclopenta[2,1-b : 3,4-b]dithiophene as the central core with triphenylamine- and carbazole-based side groups was synthesized and evaluated for perovskite solar cells. The correlations of the chem. structure of the HTMs on the photovoltaic performance were explored through different combinations of the central π-bridge moieties. The optical and electrochem. properties, energy levels, and hole mobility were systematically investigated, revealing the significant influence of the central core planarity and packing structure on their photovoltaic performance. The optimized device based on CT1 exhibited a PCE (power conversion efficiency) of 17.71% with a device architecture of FTO/TiO2 compact layer/TiO2 mesoporous/CH3NH3PbI3/HTM/MoO3/Ag, which was found to be on par with that of a cell fabricated based on state-of-the-art spiro-OMeTAD (16.97%) as HTM. Moreover, stability assessment showed an improved stability for CPDT-based HTMs in comparison with spiro-OMeTAD over 1300 h. In the experiment, the researchers used many compounds, for example, 1-Bromo-4-iodobenzene(cas: 589-87-7Quality Control of 1-Bromo-4-iodobenzene)

1-Bromo-4-iodobenzene(cas: 589-87-7) is mainly used as the OLED pharmaceutical intermediate, as reagent for in situ desilylation and coupling of silylated alkynes, as substrate in copper-free Sonogashira coupling in aqueous acetone..Quality Control of 1-Bromo-4-iodobenzene It is also used in synthesis of β,β,dibromostyrenes, as starting reagent in the total syntheses of ent-conduramine A and ent-7-deoxypancratistatin (alkaloids)

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com