Category: iodides-buliding-blocks

Kusakabe, Yu published the artcileImidazole Acceptor for Both Vacuum-Processable and Solution-Processable Efficient Blue Thermally Activated Delayed Fluorescence, Computed Properties of 364-12-5, the publication is ACS Omega (2022), 7(19), 16740-16745, database is CAplus and MEDLINE.

The members of the imidazole family have been widely used for electron transporting, host, conventional fluorescent, and phosphorescent materials. Although the imidazole core also has great potential as an acceptor segment of deep-blue thermally activated delayed fluorescence (TADF) owing to its high triplet energy, the emission color of imidazole-based TADF organic light-emitting diodes (OLEDs) has so far been limited to blue to green. In this work, four acridan-imidazole systems are theor. designed aiming for deep- or pure-blue emitters. All four emitters exhibit deep-blue to blue emission owing to the high energy levels of the lowest excited singlet states, exhibiting y coordinates of Commission Internationale de l’Eclairage coordinates between 0.06 and 0.26. The mol. composed of a trifluoromethyl-substituted benzimidazole acceptor in combination with a tetramethyl-9,10-dihydroacridine donor (named MAc-FBI) achieves a high maximum external quantum efficiency (EQE_MAX) of 13.7% in its application to vacuum-processed OLEDs. The emitter has high solubility even in ecofriendly nonhalogenated solvents, which motivates us to fabricate solution-processed MAc-FBI-based OLEDs, resulting in an even higher EQE_MAX of 16.1%.

ACS Omega published new progress about 364-12-5. 364-12-5 belongs to iodides-buliding-blocks, auxiliary class Trifluoromethyl,Fluoride,Bromide,Iodide,Benzene, name is 5-Bromo-2-iodobenzotrifluoride, and the molecular formula is C7H3BrF3I, Computed Properties of 364-12-5.

Referemce:
https://en.wikipedia.org/wiki/Iodide,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Takaishi, Tomohiro published the artcileMultigram-scale and column chromatography-free synthesis of L-azetidine-2-carboxylic acid for the synthesis of nicotianamine and its derivatives, SDS of cas: 161370-66-7, the publication is Heterocycles (2018), 96(12), 2126-2134, database is CAplus.

Multigram-scale synthesis of L-azetidine-2-carboxylic acid from L-aspartic acid was achieved in 13 conventional synthetic steps, without the need for purification by silica-gel column chromatog. and expensive reagents. Nicotianamine and its fluorescence-labeled derivatives could be obtained from this synthetic strategy.

Heterocycles published new progress about 161370-66-7. 161370-66-7 belongs to iodides-buliding-blocks, auxiliary class Chiral,Iodide,Amine,Aliphatic hydrocarbon chain,Ester,Amide, name is (S)-tert-Butyl 2-((tert-butoxycarbonyl)amino)-4-iodobutanoate, and the molecular formula is C8H15NO, SDS of cas: 161370-66-7.

Referemce:
https://en.wikipedia.org/wiki/Iodide,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Chen, Chen published the artcilePhoto-selective chain end transformation of polyacrylate-iodide using cysteamine and its application to facile single-step preparation of patterned polymer brushes, Application In Synthesis of 31253-08-4, the publication is Chemical Communications (Cambridge, United Kingdom) (2018), 54(97), 13738-13741, database is CAplus and MEDLINE.

Cysteamine, which is an inexpensive and non-toxic aminothiol, was successfully employed as a photo-selective chain end transformation agent of iodo-terminated polymer chains (polymer-I). Polymer-I was selectively transformed to hydrogen-terminated (polymer-H) and thiol-terminated (polymer-SH) polymers with and without UV irradiation, resp. This method is applicable to acrylate polymers. This photo-selective reaction offered a single-step preparation of patterned polymer brushes with SH and H chain end functionalities as a unique application.

Chemical Communications (Cambridge, United Kingdom) published new progress about 31253-08-4. 31253-08-4 belongs to iodides-buliding-blocks, auxiliary class Iodide,Ester, name is Ethyl 2-Iodopropionate, and the molecular formula is C5H9IO2, Application In Synthesis of 31253-08-4.

Referemce:
https://en.wikipedia.org/wiki/Iodide,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Boerdalen, Bjoern E. published the artcileOsmotic properties of some contrast media, Safety of 2-(3,5-Diiodo-4-oxopyridin-1(4H)-yl)acetic acid, the publication is Investigative Radiology (1970), 5(6), 559-65, database is CAplus and MEDLINE.

The contrast media, when compared on the basis of I concentration, showed only minor differences in osmolality and water activity when calculated from concentrations and osmotic coefficients A plot of osmolality vs. I concentration for different contrast media showed a slightly curved line with Angio-Conray at the top and isopaque 260 at the bottom. The mols. of some of the contrast media deviated from the theoretically assumed spherical sym.

Investigative Radiology published new progress about 101-29-1. 101-29-1 belongs to iodides-buliding-blocks, auxiliary class Pyridine,Iodide,Carboxylic acid,Ketone, name is 2-(3,5-Diiodo-4-oxopyridin-1(4H)-yl)acetic acid, and the molecular formula is C7H5I2NO3, Safety of 2-(3,5-Diiodo-4-oxopyridin-1(4H)-yl)acetic acid.

Referemce:
https://en.wikipedia.org/wiki/Iodide,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Xiao, Yufeng published the artcileDiscovery of histone deacetylase 3 (HDAC3)-specific PROTACs, Synthetic Route of 39115-95-2, the publication is Chemical Communications (Cambridge, United Kingdom) (2020), 56(68), 9866-9869, database is CAplus and MEDLINE.

Histone deacetylases (HDACs) are validated drug targets for cancer treatment. Increased HDAC isoenzyme selectivity and novel strategies to inhibit HDAC activity could lead to safer and more effective drug candidates. Nonetheless, it is quite challenging to develop isoenzyme-specific HDACi due to the highly conserved catalytic domain. We discovered XZ9002, a first-in-class HDAC3-specific PROTAC that potently degraded HDAC3. Importantly, XZ9002 is more effective to inhibit cancer cell proliferation than its proteolysis-inactive counterpart, suggesting HDAC3 degradation is a novel and promising anticancer approach.

Chemical Communications (Cambridge, United Kingdom) published new progress about 39115-95-2. 39115-95-2 belongs to iodides-buliding-blocks, auxiliary class Iodide,Hydrazine,Amine,Benzene,Hydrazide,Amide, name is 4-Iodobenzohydrazide, and the molecular formula is C4H3Cl2N3, Synthetic Route of 39115-95-2.

Referemce:
https://en.wikipedia.org/wiki/Iodide,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Mostad, Asbj published the artcilePyridine-iodomonochloride. Charge transfer complex studied by ESCA [electron spectroscopy for chemical analysis], COA of Formula: C5H5ClIN, the publication is Chemical Physics Letters (1973), 23(2), 157-9, database is CAplus.

The charge transfer complex pyridine-ICl and its dissociation components were studied at equilibrium in the gas phase by means of ESCA. At. core energy shifts in the complex relative to its components are: N 1s: +0.9 eV, I 3d: -0.8 eV, Cl 2p: <0.3 eV. If the potential model is used, these shifts suggest a transfer of 0.1 electrons from the N to the I atom in the complex.

Chemical Physics Letters published new progress about 6443-90-9. 6443-90-9 belongs to iodides-buliding-blocks, auxiliary class Pyridines, name is Pyridine Iodochloride complex, and the molecular formula is C5H5ClIN, COA of Formula: C5H5ClIN.

Referemce:
https://en.wikipedia.org/wiki/Iodide,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Bojarska-Dahlig, Halina published the artcileFeasibility of synthesizing 3,5-diiodo-4-pyridoxyacetic acid, the isomer of 3,5-diiodo-4-pyridone-N-acetic acid, Quality Control of 101-29-1, the publication is Acta Poloniae Pharmaceutica (1957), 457-8, database is CAplus.

The Ag salt of 3,5-diiodo-4-hydroxypyridine and ClCH₂CO₂Et in xylene or C₅H₅N give Et 3,5-diiodo-4-pyridone-N-acetate (I), m. 178-9°. The O-substituted isomer is not formed. The identity of I was established by determination of the mixed m.p. of I and of the free acid from I (m. 241-2°) with pure compounds prepared by a different method.

Acta Poloniae Pharmaceutica published new progress about 101-29-1. 101-29-1 belongs to iodides-buliding-blocks, auxiliary class Pyridine,Iodide,Carboxylic acid,Ketone, name is 2-(3,5-Diiodo-4-oxopyridin-1(4H)-yl)acetic acid, and the molecular formula is C7H5I2NO3, Quality Control of 101-29-1.

Referemce:
https://en.wikipedia.org/wiki/Iodide,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Bodroux, F. published the artcileTransformation of Esters of α-Bromaliphatic Acids into the Corresponding α-Iodine Derivatives, Safety of Ethyl 2-Iodopropionate, the publication is Compt. rend. (1907), 1216-17, database is CAplus.

Ethyl α-chloracetate reacts with magnesium iodide giving ethyl iodacetate (Ibid, 140, 1597). The authors find that the α-brom substituted esters react in a smooth manner with magnesium iodide in ether giving the iodine derivatives. Experimental: Ethyl iodacetate, ICH₂.CO₂C₂H₄. b₂₄ 85-86°; d₂₄ 1.762. Ethyl α-iodpropionate, CH₂.CHI.CO₂C₂H₄, b₂₄ 85°, d₁₇ 1.662. Ethyl α-iodbutyrate, C₂H₅CHI.CO₂C₂H₄, b₂₁ 100-101°; d₁₇ 1.570. The iodine-substituted esters are unstable and decompose under influence of light and heat with liberation of iodine. They volatilize at ordinary temperature

Compt. rend. published new progress about 31253-08-4. 31253-08-4 belongs to iodides-buliding-blocks, auxiliary class Iodide,Ester, name is Ethyl 2-Iodopropionate, and the molecular formula is C5H9IO2, Safety of Ethyl 2-Iodopropionate.

Referemce:
https://en.wikipedia.org/wiki/Iodide,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Bodroux, F. published the artcileTransformation of Esters of Aliphatic α-Brom Acids into the Corresponding Iodo Compounds, Synthetic Route of 31253-08-4, the publication is Bulletin de la Societe Chimique de France (1908), 909-11, database is CAplus.

By means of magnesium iodide in ethereal solution, ethyl bromacetate is converted into ethyl iodoacetate, b₂₅ 85-6°, d₂₄=1.702. Ethyl a-iodopropionate, C₅H₉O₂I, liquid, slightly colored, irritating odor, b₃₈ 85°, b₇₆₅ 181-3° with partial decomposition, d₁₇=1.662. Ethyl a-iodobutyrate, C₆H₁₁O₂I, colorless liquid, odor like pippin apples, b. 195-8° with partial decomposition, d₁₇=1.570.

Bulletin de la Societe Chimique de France published new progress about 31253-08-4. 31253-08-4 belongs to iodides-buliding-blocks, auxiliary class Iodide,Ester, name is Ethyl 2-Iodopropionate, and the molecular formula is C5H9IO2, Synthetic Route of 31253-08-4.

Referemce:
https://en.wikipedia.org/wiki/Iodide,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Mizota, Isao published the artcileTandem N,N-Dialkylation Reaction of N-Trimethylsilyl α-Iminoesters Utilizing an Umpolung Reaction and Characteristics of the Silyl Substituent: Synthesis of Pyrrolidine, Piperidine, and Iminodiacetate, Quality Control of 31253-08-4, the publication is Organic Letters (2019), 21(8), 2663-2667, database is CAplus and MEDLINE.

Umpolung reactions of N-trimethylsilyl α-iminoester with organometallics gave directly N-alkylaminoesters in high yields without the need for removing a protecting group at the nitrogen atom. Efficient syntheses of pyrrolidines, piperidines, and iminodiacetate derivatives were also developed via tandem N,N- or N,C-dialkylation reactions utilizing characteristics of the silyl substituent. Furthermore, under the influence of silica gel, the addition of an enolate to the imino nitrogen proceeded to give an iminodiacetate derivative

Organic Letters published new progress about 31253-08-4. 31253-08-4 belongs to iodides-buliding-blocks, auxiliary class Iodide,Ester, name is Ethyl 2-Iodopropionate, and the molecular formula is C5H9IO2, Quality Control of 31253-08-4.

Referemce:
https://en.wikipedia.org/wiki/Iodide,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com