iodides-buliding-blocks Archives - Page 112 of 923

Malet-Sanz, Laia’s team published research in Tetrahedron Letters in 50 | CAS: 364-12-5

Tetrahedron Letters published new progress about 364-12-5. 364-12-5 belongs to iodides-buliding-blocks, auxiliary class Trifluoromethyl,Fluoride,Bromide,Iodide,Benzene, name is 5-Bromo-2-iodobenzotrifluoride, and the molecular formula is C7H3BrF3I, Recommanded Product: 5-Bromo-2-iodobenzotrifluoride.

Malet-Sanz, Laia published the artcileA safe and reliable procedure for the iododeamination of aromatic and heteroaromatic amines in a continuous flow reactor, Recommanded Product: 5-Bromo-2-iodobenzotrifluoride, the publication is Tetrahedron Letters (2009), 50(52), 7263-7267, database is CAplus.

A method for the safe and reliable iododeamination of aromatic and heteroaromatic amines under copper-free conditions is described and its scope is evaluated. In all the experiments 1.5 equiv of t-BuONO was used and the amount of iodine was kept at 1 mol equivalent E.g., under these conditions, 4-NCC₆H₄NH₂ gave 91% 4-NCC₆H₄I.

Referemce:
https://en.wikipedia.org/wiki/Iodide,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Metzger, Juergen O.’s team published research in Angewandte Chemie, International Edition in English in 34 | CAS: 31253-08-4

Angewandte Chemie, International Edition in English published new progress about 31253-08-4. 31253-08-4 belongs to iodides-buliding-blocks, auxiliary class Iodide,Ester, name is Ethyl 2-Iodopropionate, and the molecular formula is C5H9IO2, Product Details of C5H9IO2.

Metzger, Juergen O. published the artcileRadical additions of activated haloalkanes to alkenes initiated by electron transfer from copper in solvent-free systems, Product Details of C5H9IO2, the publication is Angewandte Chemie, International Edition in English (1995), 34(8), 902-4, database is CAplus.

The solventless first radical addition of alkyl α-iodocarboxylates or α-iodoalkanenitriles to alkenes over copper metal involves an electron transfer initiated mechanism. The synthetic utility of this method is discussed.

Referemce:
https://en.wikipedia.org/wiki/Iodide,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Metzger, Jurgen O.’s team published research in Liebigs Annalen/Recueil in | CAS: 31253-08-4

Liebigs Annalen/Recueil published new progress about 31253-08-4. 31253-08-4 belongs to iodides-buliding-blocks, auxiliary class Iodide,Ester, name is Ethyl 2-Iodopropionate, and the molecular formula is C5H9IO2, COA of Formula: C5H9IO2.

Metzger, Jurgen O. published the artcileRadical additions of alkyl 2-haloalkanoates and 2-haloalkanenitriles to alkenes initiated by electron transfer from copper in solvent-free systems, COA of Formula: C5H9IO2, the publication is Liebigs Annalen/Recueil (1997), 2303-2313, database is CAplus.

Alkyl 2-iodoalkanoates and 2-iodoalkanenitriles were added with Cu powder to the 1-alkenes RCH₂CH:CH₂ [R = (CH₂)₇CO₂Me, (CH₂)₄Me, OH, C(CO₂Et)₂CH₂CH:CH₂] and to the alkenes (Z)-R(CH₂)₂CH:CH(CH₂)₂R¹ [R = (CH₂)₅Me, R¹ = (CH₂)₅CO₂Me; R = (CH₂)₅Me, R¹ = (CH₂)₉CO₂Me; R = (CH₂)₈Me, R¹ = (CH₂)₂CO₂Me; RR¹ = bond] to give γ-lactones and 4-iodoalkanenitriles, resp., in very good yields. No solvent was used. The reaction is a free-radical addition initiated by electron transfer from Cu to the activated iodoalkane. Yields were lower using the resp. bromo compounds In-situ formation of the iodo compounds by addition of stoichiometric amounts of NaI to the reaction mixture gave improved yields. In the case of bromomalonates, the addition of NaI proved to be unnecessary. The diastereoselectivity of the addition reaction by relative 1,3-asym. induction was rationalized by consideration of the steric interactions of the substituents in the transition state which is formed in the process of I transfer to the chiral adduct radical.

Referemce:
https://en.wikipedia.org/wiki/Iodide,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Soldatova, Natalia S. et al. published their research in Advanced Synthesis & Catalysis in 2021 | CAS: 139139-80-3

Bis(2,4,6-trimethylphenyl)iodonium triflate (cas: 139139-80-3) belongs to iodide derivatives. Indole, also called Benzopyrrole, a heterocyclic organic compound occurring in some flower oils, such as jasmine and orange blossom, in coal tar, and in fecal matter. Moreover, it is known that it controls biofilm formation. However, the role of indole in the cell has not been fully elucidated.Formula: C19H22F3IO3S

Copper-Catalyzed Selective N-Arylation of Oxadiazolones by Diaryliodonium Salts was written by Soldatova, Natalia S.;Semenov, Artem V.;Geyl, Kirill K.;Baykov, Sergey V.;Shetnev, Anton A.;Konstantinova, Anna S.;Korsakov, Mikhail M.;Yusubov, Mekhman S.;Postnikov, Pavel S.. And the article was included in Advanced Synthesis & Catalysis in 2021.Formula: C19H22F3IO3S The following contents are mentioned in the article:

The method for copper-catalyzed N-arylation of diverse oxadiazolones I (R¹ = cyclopropyl, Ph, 5-methylthiophen-2-yl, etc.) by diaryliodonium salts R²I⁺(R³)R^4- (R² = Ph, 3-(trifluoromethyl)phenyl, 4-nitrophenyl, etc.; R³ = Ph, 2,4,6-trimethoxyphenyl, 4-bromophenyl, etc.) under mild conditions in high yields (up to 92%) using available CuI as a catalyst was reported. The developed method allows utilizing both sym. and unsym. diaryliodonium salts bearing auxiliary groups such as 2,4,6-trimethoxyphenyl (TMP). The steric effects in aryl moieties determined the chemoselectivity of N- and O-arylation of the 1,2,4-oxadiazol-5(4H)-ones I. Mesityl-substituted diaryliodonium salts demonstrated the high potential as a selective arylation reagent. The structural study suggests that steric accessibility of N-atom in 1,2,4-oxadiazol-5(4H)-ones I impacts the arylation with sterically hindered diaryliodonium salts. The synthetic application of proposed method was also demonstrated on selective arylation of 1,3,4-oxadiazol-2(3H)-ones II and 3-(p-Tolyl)-1,2,4-oxadiazole-5-thiol. This study involved multiple reactions and reactants, such as Bis(2,4,6-trimethylphenyl)iodonium triflate (cas: 139139-80-3Formula: C19H22F3IO3S).

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Geng, Xu et al. published their research in Tetrahedron Letters in 2014 | CAS: 139139-80-3

Bis(2,4,6-trimethylphenyl)iodonium triflate (cas: 139139-80-3) belongs to iodide derivatives. Indole could be stereoselectively alkylated with chiral cyclopentyl sulfone reagent. Due to this activity, the indole ring system has become an important component or intermediate in the synthesis of heterocycles.Formula: C19H22F3IO3S

Copper-catalyzed direct N-arylation of N-arylsulfonamides using diaryliodonium salts in water was written by Geng, Xu;Mao, Song;Chen, Liangshun;Yu, Jianjun;Han, Jianwei;Hua, Jianli;Wang, Limin. And the article was included in Tetrahedron Letters in 2014.Formula: C19H22F3IO3S The following contents are mentioned in the article:

An efficient copper-catalyzed N-arylation of N-arylsulfonamides with diaryliodonium salts is reported. The reaction employs diaryliodonium salts and N-arylsulfonamides in water at room temperature, giving the products in moderate to excellent yields. This study involved multiple reactions and reactants, such as Bis(2,4,6-trimethylphenyl)iodonium triflate (cas: 139139-80-3Formula: C19H22F3IO3S).

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Bakherad, Mohammad et al. published their research in Phosphorus, Sulfur and Silicon and the Related Elements in 2011 | CAS: 371764-70-4

2-Chloro-4-iodobenzonitrile (cas: 371764-70-4) belongs to iodide derivatives. In addition to tryptophan, indigo, and indoleacetic acid, numerous compounds obtainable from plant or animal sources contain the indole molecular structure. It is used in perfumery and in making tryptophan, an essential amino acid, and indoleacetic acid (heteroauxin), a hormone that promotes the development of roots in plant cuttings.Category: iodides-buliding-blocks

Regioselective syntheses of 1-aryl-substituted-5H-[1,3]thiazolo[3,2-a]quinazoline-5-ones during Sonogashira coupling was written by Bakherad, Mohammad;Keivanloo, Ali;Kalantar, Zahra;Keley, Vahid. And the article was included in Phosphorus, Sulfur and Silicon and the Related Elements in 2011.Category: iodides-buliding-blocks The following contents are mentioned in the article:

Reaction of 2-mercaptopropargyl quinazolin-4-one (I) with various aryl iodides catalyzed by Pd-Cu leads to the regioselective formation of 1-aryl substituted-5H-[1,3]thiazolo-[3,2-a]quinazoline-5-ones, e.g., II. This study involved multiple reactions and reactants, such as 2-Chloro-4-iodobenzonitrile (cas: 371764-70-4Category: iodides-buliding-blocks).

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Shah, Aneela et al. published their research in Journal of the Chemical Society in 1997 | CAS: 139139-80-3

Bis(2,4,6-trimethylphenyl)iodonium triflate (cas: 139139-80-3) belongs to iodide derivatives. Indole, also called Benzopyrrole, a heterocyclic organic compound occurring in some flower oils, such as jasmine and orange blossom, in coal tar, and in fecal matter. In addition to indole, the strain-release chemistry worked for numerous substrates including amines, alcohols, thiols, carboxylic acids, imidazoles, and pyrazoles.Category: iodides-buliding-blocks

Synthesis of functionalized unsymmetrical diaryliodonium salts was written by Shah, Aneela;Pike, Victor W.;Widdowson, David A.. And the article was included in Journal of the Chemical Society in 1997.Category: iodides-buliding-blocks The following contents are mentioned in the article:

A generalized synthesis of unsym. functionalized diaryliodonium salts has been developed through the direct reaction of bis(acetoxy)iodoarene derivatives with arenes in a trifluoromethanesulfonic or trifluoroacetic acid medium. This study involved multiple reactions and reactants, such as Bis(2,4,6-trimethylphenyl)iodonium triflate (cas: 139139-80-3Category: iodides-buliding-blocks).

Bis(2,4,6-trimethylphenyl)iodonium triflate (cas: 139139-80-3) belongs to iodide derivatives. Indole, also called Benzopyrrole, a heterocyclic organic compound occurring in some flower oils, such as jasmine and orange blossom, in coal tar, and in fecal matter. In addition to indole, the strain-release chemistry worked for numerous substrates including amines, alcohols, thiols, carboxylic acids, imidazoles, and pyrazoles.Category: iodides-buliding-blocks

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Liu, Li et al. published their research in Tetrahedron Letters in 2012 | CAS: 1204518-02-4

Mesityl(p-tolyl)iodonium trifluoromethanesulfonate (cas: 1204518-02-4) belongs to iodide derivatives. Indole exists overwhelmingly in the 1H-indole form as do other simple indoles. They are capable of binding to a variety of receptors with high affinity and thus have applications in a wide range of therapeutic areas.Recommanded Product: Mesityl(p-tolyl)iodonium trifluoromethanesulfonate

Pd(OAc)₂-catalyzed ligand-free cyanation of diaryliodonium salts with K₄[Fe(CN)₆] was written by Liu, Li;Li, Jian;Xu, Jiao;Sun, Jiang-tao. And the article was included in Tetrahedron Letters in 2012.Recommanded Product: Mesityl(p-tolyl)iodonium trifluoromethanesulfonate The following contents are mentioned in the article:

An effective palladium-catalyzed cyanation of diaryliodonium salts with K₄[Fe(CN)₆] in DMF at 130°C has been developed, affording the aryl nitriles in high yields via ligand-free process. This study involved multiple reactions and reactants, such as Mesityl(p-tolyl)iodonium trifluoromethanesulfonate (cas: 1204518-02-4Recommanded Product: Mesityl(p-tolyl)iodonium trifluoromethanesulfonate).

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Kasahara, Takahito et al. published their research in Angewandte Chemie, International Edition in 2014 | CAS: 1204518-02-4

Mesityl(p-tolyl)iodonium trifluoromethanesulfonate (cas: 1204518-02-4) belongs to iodide derivatives. Indole is an important structural motif of various drugs, therapeutic leads besides its prevalence in numerous natural products, agrochemicals, perfumery, and dyes. It is used in perfumery and in making tryptophan, an essential amino acid, and indoleacetic acid (heteroauxin), a hormone that promotes the development of roots in plant cuttings.Reference of 1204518-02-4

Iodonium metathesis reactions was written by Kasahara, Takahito;Jang, Young Jin;Racicot, Leanne;Panagopoulos, Dimitrios;Liang, Steven H.;Ciufolini, Marco A.. And the article was included in Angewandte Chemie, International Edition in 2014.Reference of 1204518-02-4 The following contents are mentioned in the article:

A metathesis reaction occurs when a diaryliodonium triflate is heated with an aryl iodide, resulting in the formation of a new diaryliodonium triflate. © 2014 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim. This study involved multiple reactions and reactants, such as Mesityl(p-tolyl)iodonium trifluoromethanesulfonate (cas: 1204518-02-4Reference of 1204518-02-4).

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Ackermann, Lutz et al. published their research in Organic Letters in 2011 | CAS: 1204518-02-4

Mesityl(p-tolyl)iodonium trifluoromethanesulfonate (cas: 1204518-02-4) belongs to iodide derivatives. Indole produced by Proteus, Pseudomonas, Escherichia and other species was shown to be a growth promoting factor in Arabidopsis thaliana. In addition to indole, the strain-release chemistry worked for numerous substrates including amines, alcohols, thiols, carboxylic acids, imidazoles, and pyrazoles.Electric Literature of C17H18F3IO3S

Metal-Free Direct Arylations of Indoles and Pyrroles with Diaryliodonium Salts was written by Ackermann, Lutz;Dell’Acqua, Monica;Fenner, Sabine;Vicente, Ruben;Sandmann, Rene. And the article was included in Organic Letters in 2011.Electric Literature of C17H18F3IO3S The following contents are mentioned in the article:

Direct arylations of indoles and pyrroles with differently substituted diaryliodonium salts were shown to efficiently proceed in the absence of metal catalysts. This study involved multiple reactions and reactants, such as Mesityl(p-tolyl)iodonium trifluoromethanesulfonate (cas: 1204518-02-4Electric Literature of C17H18F3IO3S).

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com