Category: iodides-buliding-blocks

Wang, Xi-cun published the artcileSynthesis of 2-aryl-5-[5′-(4”-chlorophenyl)-2′-furyl]-1,3,4-oxadiazoles under microwave irradiation, Synthetic Route of 39115-95-2, the publication is Xibei Shifan Daxue Xuebao, Ziran Kexueban (2004), 40(4), 49-51, database is CAplus.

2-Aryl-5-[5′-(4”-chlorophenyl)-2′-furyl]-1,3,4-oxadiazoles is synthesized by cyclization of 5-(4′-chlorophenyl)-2-furancarboxylic acid and aroyl hydrazines in the presence of phosphorus oxychloride under the condition of microwave irradiation This synthetic strategy compared with traditional method has advantages of high yield, elevating reaction rate and simple work-up procedure.

Xibei Shifan Daxue Xuebao, Ziran Kexueban published new progress about 39115-95-2. 39115-95-2 belongs to iodides-buliding-blocks, auxiliary class Iodide,Hydrazine,Amine,Benzene,Hydrazide,Amide, name is 4-Iodobenzohydrazide, and the molecular formula is C3H5BN2O2, Synthetic Route of 39115-95-2.

Referemce:
https://en.wikipedia.org/wiki/Iodide,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Zhang, Hao published the artcileDesign, Synthesis and Herbicidal Activities of Tetrahydroisoindoline-1,3-dione Derivatives Containing Alkoxycarbonyl Substituted 2-Benzoxazolinone, Application of Ethyl 2-Iodopropionate, the publication is Chinese Journal of Chemistry (2015), 33(7), 749-755, database is CAplus.

Several different alkoxycarbonyl-substituted 2-benzoxazolinone moieties were incorporated into a tetrahydroisoindoline-1,3-dione scaffold to provide 25 compounds (1,3-dioxo-4,5,6,7-tetrahydroisoindol-2(3H)-yl)-6-halo-alkoxycarbonyl benzoxazolinones e.g., I. The structures of these compounds were confirmed by ¹H and ¹³C NMR, HRMS and X-ray single-crystal diffraction. Some of these compounds I [R = Me propanoate, Et propanoate, ethyl-2-butanoate, ethyl-4-butanoate] exhibited excellent herbicidal activities against Abutilon theophrasti, Amaranthus retroflexus and Echinochloa crus-galli at a rate of 375 g AI·ha^-1. Among them, compounds I [R = Et propanoate, ethyl-2-butanoate] displayed the best post-emergence herbicidal effect against Abutilon theophrasti with ED₅₀ values of 1.8 and 5.3 g AI·ha^-1, resp., which are superior to that of the com. acifluorfen (44.3 g AI·ha^-1). Field trials demonstrated that compound I [R = Et propanoate] exhibited similar herbicidal activity to a high concentration atrazine, and found to be safer for maize than atrazine. The results of this study therefore show that compound I [R = Et propanoate] could potentially be used as a post-emergence herbicide for maize fields.

Chinese Journal of Chemistry published new progress about 31253-08-4. 31253-08-4 belongs to iodides-buliding-blocks, auxiliary class Iodide,Ester, name is Ethyl 2-Iodopropionate, and the molecular formula is C15H14BNO4S, Application of Ethyl 2-Iodopropionate.

Referemce:
https://en.wikipedia.org/wiki/Iodide,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Li, Qu-xiang published the artcileSynthesis and characterization of acylthiosemicarbazides containing D-acetylglucosamine, Quality Control of 39115-95-2, the publication is Huaxue Shiji (2015), 37(2), 117-121, database is CAplus.

2-Acetamido-3,4,6-tri-O-acetyl-2-deoxy-β-D-glucopyranosyl isothiocyanat, e. g., I, was synthesized through following steps, acylation, chlorination and isothiocyanate with D-glucosamine hydrochloride as starting material. The reaction of 2-acetamido-3,4,6-tri-O-acetyl-2-deoxy-β-D-glucopyranosyl isothiocyanate with various hydrazides obtained 12 novel title compounds The structures were confirmed by IR, ¹HNMR and ESI-MS, and all glycosyl derivatives kept the original β-configuration.

Huaxue Shiji published new progress about 39115-95-2. 39115-95-2 belongs to iodides-buliding-blocks, auxiliary class Iodide,Hydrazine,Amine,Benzene,Hydrazide,Amide, name is 4-Iodobenzohydrazide, and the molecular formula is C7H7IN2O, Quality Control of 39115-95-2.

Referemce:
https://en.wikipedia.org/wiki/Iodide,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Yao, Tuanli published the artcileSynthesis of Isocoumarins and α-Pyrones via Electrophilic Cyclization, Safety of Dimethyl 2-iodoterephthalate, the publication is Journal of Organic Chemistry (2003), 68(15), 5936-5942, database is CAplus and MEDLINE.

A variety of substituted isocoumarins, e.g. I [R¹ = H, MeO; R² = H, MeO, MeO₂C; R³ = HO(CH₂)₃, Ph, n-hexyl, etc.; R⁴ = H, iodo, 4-O₂NC₆H₄S, PhSe], and α-pyrones, e.g. II [R⁵ = H, Me, Ph; R⁶ = H, Ph; R⁵R⁶ = (CH₂)₃; R⁷ = Bu, Ph], are readily prepared in excellent yields under very mild reaction conditions by the reaction of o-(1-alkynyl)benzoates, e.g. III (R⁸ = Me, Me₃C), or (Z)-2-alken-4-ynoates, e.g. IV (R⁹ = Me, Et), resp., with ICl, I₂, PhSeCl, p-O₂NC₆H₄SCl, and hydrogen iodide. This methodol. accommodates various alkynyl esters and has been successfully extended to the synthesis of polycyclic aromatic and biaryl compounds

Journal of Organic Chemistry published new progress about 165534-79-2. 165534-79-2 belongs to iodides-buliding-blocks, auxiliary class Iodide,Benzene,Ester, name is Dimethyl 2-iodoterephthalate, and the molecular formula is C27H39ClN2, Safety of Dimethyl 2-iodoterephthalate.

Referemce:
https://en.wikipedia.org/wiki/Iodide,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Hammarlund, E. R. published the artcileMethods of preparing isotonic solutions by means of graphs or tables on the basis of experimentally found iso-osmotic values, Computed Properties of 101-29-1, the publication is Pharmaceutica Acta Helvetiae (1960), 593-607, database is CAplus.

Four graphical and three tabular methods for preparing isotonic aqueous solutions are described. New exptl. data is presented for 353 compounds to be used for the recommended and most practical of the methods studied for isotonicity adjustment. All the methods described may be used in practical pharmacy. The graphical methods are more accurate but consume more space than the tabular methods.

Pharmaceutica Acta Helvetiae published new progress about 101-29-1. 101-29-1 belongs to iodides-buliding-blocks, auxiliary class Pyridine,Iodide,Carboxylic acid,Ketone, name is 2-(3,5-Diiodo-4-oxopyridin-1(4H)-yl)acetic acid, and the molecular formula is C7H5I2NO3, Computed Properties of 101-29-1.

Referemce:
https://en.wikipedia.org/wiki/Iodide,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Tahmouresilerd, Babak published the artcileMake room for iodine: systematic pore tuning of multivariate metal-organic frameworks for the catalytic oxidation of hydroquinones using hypervalent iodine, Recommanded Product: Dimethyl 2-iodoterephthalate, the publication is Catalysis Science & Technology (2018), 8(17), 4349-4357, database is CAplus.

Iodine sites have been incorporated in both MIL-53 (Al) and UiO-66 (Zr) MOFs. A multivariate approach was used to increase the accessible area within the pores to allow for the catalytic oxidation of a model substrate, hydroquinone, to the corresponding quinone. In the process, three new phases of MIL-53 were discovered, one of which proved instrumental in allowing catalysis to occur. Both UiO-66 and MIL-53 with 25% incorporated iodine containing linkers allowed for a near-ideal balance between high d. of catalytic sites and sufficient space for mass transport to enable catalysis to occur. Good conversions and selectivities were observed in nitromethane, Et acetate, acetone and ethanol with UiO-66 which proved to be the more active of the two catalysts. Oxone and 3-chloroperbenzoic acid acted as competent cooxidants. XPS revealed that the reaction proceeded through an I(III) oxidation state. The MIL-53 framework was readily recycled while the UiO-66 MOF suffered from catalyst deactivation due to particle agglomeration. UiO-66 with 25% iodine containing linker proved to be a competent catalyst for a variety of substituted hydroquinones.

Catalysis Science & Technology published new progress about 165534-79-2. 165534-79-2 belongs to iodides-buliding-blocks, auxiliary class Iodide,Benzene,Ester, name is Dimethyl 2-iodoterephthalate, and the molecular formula is C12H14IN, Recommanded Product: Dimethyl 2-iodoterephthalate.

Referemce:
https://en.wikipedia.org/wiki/Iodide,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Poleshchuk, O. Kh. published the artcileStudy of the electronic structure of the ICl·Py complex, Recommanded Product: Pyridine Iodochloride complex, the publication is Russian Journal of Coordination Chemistry (Translation of Koordinatsionnaya Khimiya) (1998), 24(1), 67-71, database is CAplus.

The results of ab initio and semiempirical calculations are used to analyze the frequency changes in the NQR, X-ray fluorescence, and photoelectron spectra of the ICl·Py complex. A comparison of the calculated MO energies with the exptl. ionization potentials made it possible to explain the stability of the complex. The results obtained are used to elucidate the origin of the complexation-induced chlorine, iodine, and nitrogen NQR frequency shifts.

Russian Journal of Coordination Chemistry (Translation of Koordinatsionnaya Khimiya) published new progress about 6443-90-9. 6443-90-9 belongs to iodides-buliding-blocks, auxiliary class Pyridines, name is Pyridine Iodochloride complex, and the molecular formula is C5H5ClIN, Recommanded Product: Pyridine Iodochloride complex.

Referemce:
https://en.wikipedia.org/wiki/Iodide,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Kindt, Nadege published the artcilePharmacological inhibition of macrophage migration inhibitory factor interferes with the proliferation and invasiveness of squamous carcinoma cells, HPLC of Formula: 41270-96-6, the publication is International Journal of Oncology (2013), 43(1), 185-193, database is CAplus and MEDLINE.

Recent clin. observations and exptl. studies of our group indicate that macrophage migration inhibitory factor (MIF) may contribute to tumor progression in head and neck squamous cell carcinomas (HNSCC). The present study was undertaken to examine the effects of the irreversible MIF inhibitor 4-iodo-6-phenylpyrimidine (4-IPP) on proliferation and invasiveness of the squamous carcinoma cell line SCCVII. Cell counting, crystal violet assay and flow cytometry were used to analyze the effects of 4-IPP on SCCVII cell growth. The impact of 4-IPP on cell invasiveness was assessed by Boyden chamber assay. Knockdown of the MIF receptor CD74 was achieved by transduction with lentiviral vectors encoding anti-CD74 shRNAs. As shown by immunofluorescence staining, SCCVII cells express both MIF and CD74. Decreased MIF immunoreactivity as a result of exposure to 4-IPP suggested a covalent modification of the cytokine. 4-IPP inhibited SCCVII cell proliferation and invasiveness. Moreover, the cytostatic effect of 4-IPP was enhanced by CD74 knockdown. The inhibitory effects of 4-IPP on cell proliferation and invasiveness strongly suggest that MIF is involved in proliferative activity and invasive properties of squamous carcinoma cells. In conclusion, MIF inhibition may open possibilities for target-directed treatment of head and neck squamous cell carcinoma.

International Journal of Oncology published new progress about 41270-96-6. 41270-96-6 belongs to iodides-buliding-blocks, auxiliary class Pyrimidine,Iodide,Benzene,Immunology/Inflammation,MIF, name is 4-Iodo-6-phenylpyrimidine, and the molecular formula is C10H7IN2, HPLC of Formula: 41270-96-6.

Referemce:
https://en.wikipedia.org/wiki/Iodide,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Gaux, Bernard published the artcilePartial deiodination of polyiodo compounds with lithium aluminum hydride, COA of Formula: C7H8INO, the publication is Bulletin de la Societe Chimique de France (1974), 505-9, database is CAplus.

Triiodobenzoic acids reacted with LiAlH4 to give the resp. diiodobenzyl alcs. 3,5-Diiodanthranilic and -salicylic acids gave the resp. diiodobenzyl alcs. as well as monoiodobenzyl alcs. 4-Amino-3,5-diioidobenzoic acid gave only 3,5,4-I2(H2N)-C6H2CH2OH.

Bulletin de la Societe Chimique de France published new progress about 53279-83-7. 53279-83-7 belongs to iodides-buliding-blocks, auxiliary class Iodide,Amine,Benzene,Alcohol, name is (2-Amino-5-iodophenyl)methanol, and the molecular formula is C7H8INO, COA of Formula: C7H8INO.

Referemce:
https://en.wikipedia.org/wiki/Iodide,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Ahn, Jin Hee published the artcileA new synthesis of γ-dialkoxy carboxylic acid derivatives via radical coupling reaction of α-halo acid derivatives with vinyl ethers, Formula: C5H9IO2, the publication is Synlett (1996), 1224-1226, database is CAplus.

γ-Dialkoxy carboxylic acid derivatives were prepared conveniently by the radical coupling reaction of α-halo carboxylic acid derivatives with vinyl ethers in 65-95% yield using Ni₂B(cat.)-BER in MeOH in the presence of NaI.

Synlett published new progress about 31253-08-4. 31253-08-4 belongs to iodides-buliding-blocks, auxiliary class Iodide,Ester, name is Ethyl 2-Iodopropionate, and the molecular formula is C5H9IO2, Formula: C5H9IO2.

Referemce:
https://en.wikipedia.org/wiki/Iodide,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com