Category: iodides-buliding-blocks

Five-State Rotary Nanoswitch was written by Gaikwad, Sudhakar;Schmittel, Michael. And the article was included in Journal of Organic Chemistry in 2017.Computed Properties of C10H12I2 This article mentions the following:

In our quest to develop artificial multistate devices, we synthesized the nanomech. switch 1 that is characterized by a tetrahedral core equipped with four pending arms. The rotary arm with its azaterpyridine terminal is intramolecularly coordinated to a zinc(II) porphyrin station that is the terminus of another arm in 1. The two other arms carry identical sterically shielded phenanthroline stations. The 2-fold alternate addition of a copper(I) ion and [1,10]-phenanthroline (1 equiv each) results in the formation of five different switching states (State Iâ†?State IIâ†?State IIIâ†?State IVâ†?State V â†?State I), which force the toggling arm to move back and forth between the zinc(II) porphyrin and phenanthroline stations separated by a distance of 25 Å. All switching states constitute clean single species, except for State III, and thus are fully characterized by spectroscopic methods and elemental anal. Finally, the initial state of nanoswitch was reset by addition of cyclam for complete removal of the copper(I) ions. In the experiment, the researchers used many compounds, for example, 1,4-Diiodo-2,3,5,6-tetramethylbenzene (cas: 3268-21-1Computed Properties of C10H12I2).

1,4-Diiodo-2,3,5,6-tetramethylbenzene (cas: 3268-21-1) belongs to iodide derivatives. Organic iodides are organic compounds containing a carbon-iodine (C-I) bond. The carbon-iodine bond is weaker than other carbon-halogen bonds due to the poor electronegative nature of the iodine atom. In the chemical industry, alkyl iodides serve as excellent alkylating agents and, specifically, methyl iodide is used as a methylating agent in the synthesis of various pharmaceutical drugs.Computed Properties of C10H12I2

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Fabrication of alternating copolymers based on cyclopentadithiophene-benzothiadiazole dicarboxylic imide with reduced optical band gap: synthesis, optical, electrochemical, thermal, and structural properties was written by Murad, Ary R.;Iraqi, Ahmed;Aziz, Shujahadeen B.;Abdullah, Sozan N.;Brza, Mohamad A.;Saeed, Salah R.;Abdulwahid, Rebar T.. And the article was included in Polymers (Basel, Switzerland) in 2021.Category: iodides-buliding-blocks This article mentions the following:

A series of alternating copolymers containing cyclopentadithiophene (CPDT) flanked by thienyl moieties as electron-donor units and benzothiadiazole dicarboxylic imide (BTDI) as electron-acceptor units were designed and synthesized for solar cell applications. Different solubilizing side chains, including 2-ethylhexyl chains and n-octyl chains were attached to CPDT units, whereas 3,7-dimethyloctyl chains and n-octyl chains were anchored to the BTDI moieties. The impact of these substituents on the solubilities, mol. weights, optical and electrochem. properties, and thermal and structural properties of the resulting polymers was investigated. PCPDTDTBTDI-EH, DMO was synthesized via Suzuki polymerization, whereas PCPDTDTBTDI-8, DMO, and PCPDTDTBTDI-EH, 8 were prepared through direct arylation polymerization PCPDTDTBTDI-8, DMO has the highest number average mol. weight (M_n = 17,400 g mol-1) among all polymers prepared The PCPDTDTBTDI-8, DMO and PCPDTDTBTDI-8, 8 which have n-octyl substituents on their CPDT units have comparable optical band gaps (E_g �1.3 eV), which are around 0.1 eV lower than PCPDTDTBTDI-EH, DMO analogs that have 2-ethylhexyl substituents on their CPDT units. The polymers have their HOMO levels between -5.10 and -5.22 eV with PCPDTDTBTDI-EH, DMO having the deepest HOMO (HOMO) energy level. The LUMO (LUMO) levels of the polymers are between -3.4 and -3.5 eV. All polymers exhibit good thermal stability with decomposition temperatures surpassing 350 °C. Powder X-ray diffraction (XRD) studies have shown that all polymers have the amorphous nature in solid state. In the experiment, the researchers used many compounds, for example, Bis(2-iodothiophen-3-yl)methanone (cas: 474416-61-0Category: iodides-buliding-blocks).

Bis(2-iodothiophen-3-yl)methanone (cas: 474416-61-0) belongs to iodide derivatives. In general, organic iodides are light-sensitive and turn yellow during storage, owing to the formation of iodine. Polyiodoorganic compounds are sometimes employed as X-ray contrast agents, in fluoroscopy, a type of medical imaging. This application exploits the X-ray absorbing ability of the heavy iodine nucleus.Category: iodides-buliding-blocks

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Ligand-enabled β-C-H arylation of α-amino acids without installing exogenous directing groups was written by Chen, Gang;Zhuang, Zhe;Li, Gen-Cheng;Saint-Denis, Tyler G.;Hsiao, Yi;Joe, Candice L.;Yu, Jin-Quan. And the article was included in Angewandte Chemie, International Edition in 2017.Application In Synthesis of 4-Iodo-1,2-dimethoxybenzene This article mentions the following:

Herein we report acid-directed β-C(sp³)-H arylation of α-amino acids enabled by pyridine-type ligands. This reaction does not require the installation of an exogenous directing group, is scalable, and enables the preparation of Fmoc-protected (Fmoc = 9-fluorenylmethoxycarbonyl) unnatural amino acids in three steps. The pyridine-type ligands are crucial for the development of this new C(sp³)-H arylation. In the experiment, the researchers used many compounds, for example, 4-Iodo-1,2-dimethoxybenzene (cas: 5460-32-2Application In Synthesis of 4-Iodo-1,2-dimethoxybenzene).

4-Iodo-1,2-dimethoxybenzene (cas: 5460-32-2) belongs to iodide derivatives. Organoiodine compounds occur widely in organic chemistry, but are relatively rare in nature. Organoiodine lubricants can be used with titanium, stainless steels, and other metals which tend to seize up with conventional lubricants: organoiodine lubricants can be used in turbines and spacecraft, and as a cutting oil in machining.Application In Synthesis of 4-Iodo-1,2-dimethoxybenzene

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

A Novel Approach to Access Aryl Iodides and Disulfides via Dehydrazination of Arylhydrazines and Arylsulfonylhydrazides was written by Balgotra, Shilpi;Kumar Verma, Praveen;Kour, Jaspreet;Gupta, Sorav;Vishwakarma, Ram A.;Sawant, Sanghapal D.. And the article was included in ChemistrySelect in 2018.Safety of 4-Iodo-1,2-dimethoxybenzene This article mentions the following:

The direct iodination of arylhydrazines was achieved using I₂ and KOAc in excellent yields. In addition, disulfides were synthesized from arylsulfonylhydrazides in high yields using same catalytic system. The advantageous feature of the present protocol is the exclusion of transition metal catalyst from the reaction for dehydrazination. A number of labile functionalities remain intact during the reaction. In the experiment, the researchers used many compounds, for example, 4-Iodo-1,2-dimethoxybenzene (cas: 5460-32-2Safety of 4-Iodo-1,2-dimethoxybenzene).

4-Iodo-1,2-dimethoxybenzene (cas: 5460-32-2) belongs to iodide derivatives. Organic iodides are widely used in organic synthesis. Halogenation of aromatic hydrocarbons is a very important reaction via an electrophilic aromatic substitution. The C–I bond is the weakest of the carbon–halogen bonds. These bond strengths correlate with the electronegativity of the halogen, decreasing in the order F > Cl > Br > I.Safety of 4-Iodo-1,2-dimethoxybenzene

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Efficient Asymmetric Synthesis of Biologically Important Tryptophan Analogues via a Palladium-Mediated Heteroannulation Reaction was written by Ma, Chunrong;Liu, Xiaoxiang;Li, Xiaoyan;Flippen-Anderson, Judith;Yu, Shu;Cook, James M.. And the article was included in Journal of Organic Chemistry in 2001.HPLC of Formula: 220185-63-7 This article mentions the following:

A novel and concise synthesis of optically active tryptophan derivatives was developed via a palladium-catalyzed heteroannulation reaction of substituted o-iodoanilines with an internal alkyne. The required internal alkyne I was prepared in greater than 96% diastereomeric excess via alkylation of the Schollkopf chiral auxiliary, 3,6-diethoxy-2R-isopropyl-2,5-dihydropyrazine with Me₃SiCCCH₂OP(:O)(OPh)₂. Similarly, alkyne II was obtained from the alkylation of 3,6-diethoxy-2S-isopropyl-2,5-dihydropyrazine by TMSCCCH₂OP(:O)(OPh)₂. I was used as an intermediate in the palladium-catalyzed heteroannulation reaction to afford L-tryptophan analogs, whereas II afforded D-tryptophan analogs. Using this strategy, the first asym. syntheses of L-isotryptophan (III) and L-benz[f]tryptophan (IV) were realized. In addition, the optically pure Et 6-methoxy-D-tryptophanate (V) was prepared by this protocol on a large scale (>300 g). An improved total synthesis of tryprostatin A (VI) was accomplished in 43% overall yield employing this palladium-mediated process. In the experiment, the researchers used many compounds, for example, 4,5-Dichloro-2-iodoaniline (cas: 220185-63-7HPLC of Formula: 220185-63-7).

4,5-Dichloro-2-iodoaniline (cas: 220185-63-7) belongs to iodide derivatives. In general, organic iodides are light-sensitive and turn yellow during storage, owing to the formation of iodine. Polyiodoorganic compounds are sometimes employed as X-ray contrast agents, in fluoroscopy, a type of medical imaging. This application exploits the X-ray absorbing ability of the heavy iodine nucleus.HPLC of Formula: 220185-63-7

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Synthesis of 4-[3,4-di-(2,3,4-tri)methoxyphenyl]benzo[e]-1,2-oxaphosphorines was written by Aniskin, A. S.;Nemtarev, A. V.;Baranov, D. S.;Vasilevskii, S. F.;Mironov, V. F.. And the article was included in Russian Journal of General Chemistry in 2015.Related Products of 5460-32-2 This article mentions the following:

In this work, the behavior of 2,2,2-trichlorobenzo-1,3,2-dioxaphospholes in the reactions with 3,4-dimethoxy-2,3,4-trimetoxyphenylacetylenes containing several donor substituents was studied with the aim to develop a convenient method for the synthesis of polymethoxylated areno-1,2-oxaphospholes. In the experiment, the researchers used many compounds, for example, 4-Iodo-1,2-dimethoxybenzene (cas: 5460-32-2Related Products of 5460-32-2).

4-Iodo-1,2-dimethoxybenzene (cas: 5460-32-2) belongs to iodide derivatives. Iodide-containing intermediates are common in organic synthesis, because of the easy formation and cleavage of the C–I bond. Organoiodine lubricants can be used with titanium, stainless steels, and other metals which tend to seize up with conventional lubricants: organoiodine lubricants can be used in turbines and spacecraft, and as a cutting oil in machining.Related Products of 5460-32-2

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Cationic palladium(II)-catalyzed synthesis of 2-substituted 3-hydroxymethylbenzo[b]furans was written by Wang, Huan;Han, Xiuling;Lu, Xiyan. And the article was included in Synlett in 2011.Electric Literature of C6H4BrIO This article mentions the following:

A tandem reaction involving an intramol. oxypalladation of an alkyne and an addition to the carbonyl group to quench the carbon-palladium bond to complete the catalytic cycle was developed. The reaction of 2-alkynylphenols with aldehydes to prepare substituted 3-(hydroxymethyl)benzofurans in one pot is described. E.g, reaction of 2-(phenylethynyl)phenol and p-nitrobenzaldehyde, catalyzed by [Pd(dppp)(H₂O)₂](BF₄)₂, gave 90% benzofuran (I). The reaction was catalyzed with the cationic palladium(II) species without the necessity of a redox system. In the experiment, the researchers used many compounds, for example, 4-Bromo-2-iodophenol (cas: 207115-22-8Electric Literature of C6H4BrIO).

4-Bromo-2-iodophenol (cas: 207115-22-8) belongs to iodide derivatives. Organic iodides can be alkyl, alkenyl, or alkynyl, and all of them are very reactive toward with many kinds of nucleophiles. The C–I bond is the weakest of the carbon–halogen bonds. These bond strengths correlate with the electronegativity of the halogen, decreasing in the order F > Cl > Br > I. This periodic order also follows the atomic radius of halogens and the length of the carbon-halogen bond.Electric Literature of C6H4BrIO

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Dissecting Porosity in Molecular Crystals: Influence of Geometry, Hydrogen Bonding, and [π···π] Stacking on the Solid-State Packing of Fluorinated Aromatics was written by Hashim, Mohamed I.;Le, Ha T. M.;Chen, Teng-Hao;Chen, Yu-Sheng;Daugulis, Olafs;Hsu, Chia-Wei;Jacobson, Allan J.;Kaveevivitchai, Watchareeya;Liang, Xiao;Makarenko, Tatyana;Miljanic, Ognjen S.;Popovs, Ilja;Tran, Hung Vu;Wang, Xiqu;Wu, Chia-Hua;Wu, Judy I.. And the article was included in Journal of the American Chemical Society in 2018.Electric Literature of C10H12I2 This article mentions the following:

Porous mol. crystals are an emerging class of porous materials that is unique in being built from discrete mols. rather than being polymeric in nature. In this study, we examined the effects of mol. structure of the precursors on the formation of porous solid-state structures with a series of 16 rigid aromatics The majority of these precursors possess pyrazole groups capable of hydrogen bonding, as well as electron-rich aromatics and electron-poor tetrafluorobenzene rings. These precursors were prepared using a combination of Pd- and Cu-catalyzed cross-couplings, careful manipulations of protecting groups on the nitrogen atoms, and solvothermal syntheses. Our study varied the geometry and dimensions of precursors, as well as the presence of groups capable of hydrogen bonding and [π···π] stacking. Thirteen derivatives were crystallog. characterized, and four of them were found to be porous with surface areas between 283 and 1821 m² g^-1. Common to these four porous structures were (a) rigid trigonal geometry, (b) [π···π] stacking of electron-poor tetrafluorobenzenes with electron-rich pyrazoles or tetrazoles, and (c) hydrogen bonding between the terminal heteroaromatic rings. In the experiment, the researchers used many compounds, for example, 1,4-Diiodo-2,3,5,6-tetramethylbenzene (cas: 3268-21-1Electric Literature of C10H12I2).

1,4-Diiodo-2,3,5,6-tetramethylbenzene (cas: 3268-21-1) belongs to iodide derivatives. Generally organic iodides can be divided into two classes of alkyl iodides and aryl iodides. Typical reactions of alkyl iodides include nucleophilic substitution, elimination, reduction, and the formation of organometallics. In the chemical industry, alkyl iodides serve as excellent alkylating agents and, specifically, methyl iodide is used as a methylating agent in the synthesis of various pharmaceutical drugs.Electric Literature of C10H12I2

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Neurotropic and psychotropic agents. LXVII. 9-Chloro-10-(4-methylpiperazino)-10,11-dihydrodibenzo[b,f]thiepin and some related synthetic experiments was written by Sindelar, K.;Kakac, B.;Svatek, E.;Holubek, J.;Rajsner, M.;Metysova, J.;Protiva, M.. And the article was included in Collection of Czechoslovak Chemical Communications in 1974.SDS of cas: 13420-63-8 This article mentions the following:

The title compound (I) was prepared in 9 steps from 1-chloro-4-nitrothioxanthone. The decisive step of the synthesis was the oxidation of 1-chloro-9-methylenethioxanthene (II) with Tl(NO3)3 in MeOH; the principal product was the enol-ether III which was hydrolyzed to 9-chlorodibenzo[b,f]thiepin-10(11H)-one (IV). The by-products of the oxidation reaction were 1-chlorodibenzo-[b,f]thiepin-10(11H)-one, bi[1-chloro-11-methoxy-10,11-dihydrodibenzo[b,f]thiepin-10-yl], bi[1-chlorodibenzo[b,f]thiepin-10-yl], and Me 1-chlorothioxanthene-9-carboxylate. IV was transformed to I via 9-chloro-10-hydroxy-10,11-dihydrodibenzo[b,f]-thiepin and 9,10-dichloro-10,11-dihydrodibenzo[b,f]thiepin. An attempt at cyclization of 2-(2-acetamido-5-chlorophenylthio)-phenylacetic acid with H3PO4 acid in the presence of PhMe gave 2-chloro-5H-dibenzo[b,g]-1,4-thiazocin-6(7H)-one (V) and two other products resulting from interaction of the amide group with PhMe, and assumed to be 2-chloro-6-(4-tolyl)-7H-dibenzo-[b,g]-1,4-thiazocine and 6-[1-(4-tolyl)-1-ethylideneamino]-9-chlorodibenzo[b,f]thiepin-10(11H)-one. In the experiment, the researchers used many compounds, for example, 2-Chloro-6-iodobenzoic acid (cas: 13420-63-8SDS of cas: 13420-63-8).

2-Chloro-6-iodobenzoic acid (cas: 13420-63-8) belongs to iodide derivatives. Organoiodine compounds occur widely in organic chemistry, but are relatively rare in nature. Polyiodoorganic compounds are sometimes employed as X-ray contrast agents, in fluoroscopy, a type of medical imaging. This application exploits the X-ray absorbing ability of the heavy iodine nucleus.SDS of cas: 13420-63-8

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Difluorocarbene-Based Cyanation of Aryl Iodides was written by Zhang, Yin-Xiang;Xiao, Xuan;Fu, Zhi-Hong;Lin, Jin-Hong;Guo, Yu;Yao, Xu;Cao, Yu-Cai;Du, Ruo-Bing;Zheng, Xing;Xiao, Ji-Chang. And the article was included in Synlett in 2020.Quality Control of 3-Iodobenzo[b]thiophene This article mentions the following:

Herein, a difluorocarbene-based cyanation of aryl iodides promoted by a cheap copper source, Cu(NO₃)₂·2.5H₂O, under an air atm is reported. Difluoromethylene phosphobetaine (Ph₃P⁺CF₂CO₂^–), an easily available and shelf-stable difluorocarbene reagent, and NaNH₂ are used as the carbon source and the nitrogen source for the nitrile group, resp. The cyanation protocol is attractive because no toxic reagent is used and performing the reactions under an air atm. is operationally convenient. In the experiment, the researchers used many compounds, for example, 3-Iodobenzo[b]thiophene (cas: 36748-88-6Quality Control of 3-Iodobenzo[b]thiophene).

3-Iodobenzo[b]thiophene (cas: 36748-88-6) belongs to iodide derivatives. In general, organic iodides are light-sensitive and turn yellow during storage, owing to the formation of iodine. In the chemical industry, alkyl iodides serve as excellent alkylating agents and, specifically, methyl iodide is used as a methylating agent in the synthesis of various pharmaceutical drugs.Quality Control of 3-Iodobenzo[b]thiophene

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com