Category: iodides-buliding-blocks

Mannancherry, Rajesh published the artcileMolecular dynamic staircases: all-carbon axial chiral “Geländer” structures, Name: Dimethyl 2-iodoterephthalate, the publication is Chemical Science (2018), 9(26), 5758-5766, database is CAplus and MEDLINE.

Herein, the syntheses of two tightly packed all-carbon “Geländer” mols. with axial chirality are described. Motivated by our previous results, we further reduced the bridge length by excluding the heteroatoms. The absolute configuration was determined by comparison of the measured and calculated CD (CD) spectra and the thermodn. stability was determined by dynamic high-performance liquid chromatog. (HPLC) and CD anal. The cyclophanes were fully characterized by CD measurements, X-ray diffraction (XRD) anal., NMR, UV-Vis and high resolution mass spectrometry (HRMS). Our novel all-carbon macrocycle is the most stable Geländer system reported so far.

Chemical Science published new progress about 165534-79-2. 165534-79-2 belongs to iodides-buliding-blocks, auxiliary class Iodide,Benzene,Ester, name is Dimethyl 2-iodoterephthalate, and the molecular formula is C10H9IO4, Name: Dimethyl 2-iodoterephthalate.

Referemce:
https://en.wikipedia.org/wiki/Iodide,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Gleede, Tassilo published the artcileInvestigation of S_N2 [¹¹C]cyanation for base-sensitive substrates: an improved radiosynthesis of L-[5-¹¹C]-glutamine, Computed Properties of 161370-66-7, the publication is Amino Acids (2015), 47(3), 525-533, database is CAplus and MEDLINE.

Carbon-11 (β⁺ emitter, t_1/2 = 20.4 min) radiolabeled L-glutamine is a potentially useful mol. imaging agent that can be utilized with positron emission tomog. for both human oncol. diagnosis and plant imaging research. Based upon a previously reported [¹¹C]cyanide end-capping labeling method, a systematic investigation of nucleophilic cyanation reactions and acidic hydrolysis reaction parameters, including base, metal ion source, phase transfer catalyst, solvent, reaction temperature and reaction time, was conducted. The result was a milder, more reliable, two-step method which provides L-[5-¹¹C]-glutamine with a radiochem. yield of 63.8 ± 8.7% (range from 51 to 74%, n = 10) with >90% radiochem. purity and >90% enantiomeric purity. The total synthesis time was 40-50 min from the end of bombardment. In addition, an Fmoc derivatization method was developed to measure the specific activity of this radiotracer.

Amino Acids published new progress about 161370-66-7. 161370-66-7 belongs to iodides-buliding-blocks, auxiliary class Chiral,Iodide,Amine,Aliphatic hydrocarbon chain,Ester,Amide, name is (S)-tert-Butyl 2-((tert-butoxycarbonyl)amino)-4-iodobutanoate, and the molecular formula is C13H24INO4, Computed Properties of 161370-66-7.

Referemce:
https://en.wikipedia.org/wiki/Iodide,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Cisneros, Jose A. published the artcileA Fluorescence Polarization Assay for Binding to Macrophage Migration Inhibitory Factor and Crystal Structures for Complexes of Two Potent Inhibitors, Computed Properties of 41270-96-6, the publication is Journal of the American Chemical Society (2016), 138(27), 8630-8638, database is CAplus and MEDLINE.

Human macrophage migration inhibitory factor (MIF) is both a keto-enol tautomerase and a cytokine associated with numerous inflammatory diseases and cancer. Consistent with observed correlations between inhibition of the enzymic and biol. activities, discovery of MIF inhibitors has focused on monitoring the tautomerase activity using L-dopachrome Me ester or 4-hydroxyphenyl pyruvic acid as substrates. The accuracy of these assays is compromised by several issues including substrate instability, spectral interference, and short linear periods for product formation. In this work, we report the syntheses of fluorescently labeled MIF inhibitors and their use in the first fluorescence polarization-based assay to measure the direct binding of inhibitors to the active site. The assay allows the accurate and efficient identification of competitive, noncompetitive, and covalent inhibitors of MIF in a manner that can be scaled for high-throughput screening. The results for 22 compounds show that the most potent MIF inhibitors bind with K_d values of ca. 50 nM; two are from our laboratory, and the other is a compound from the patent literature. X-ray crystal structures for two of the most potent compounds bound to MIF are also reported here. Striking combinations of protein-ligand hydrogen bonding, aryl-aryl, and cation-π interactions are responsible for the high affinities. A new chem. series was then designed using this knowledge to yield two more strong MIF inhibitors/binders.

Journal of the American Chemical Society published new progress about 41270-96-6. 41270-96-6 belongs to iodides-buliding-blocks, auxiliary class Pyrimidine,Iodide,Benzene,Immunology/Inflammation,MIF, name is 4-Iodo-6-phenylpyrimidine, and the molecular formula is C10H7IN2, Computed Properties of 41270-96-6.

Referemce:
https://en.wikipedia.org/wiki/Iodide,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Mikitenko, E. K. published the artcileCyclazines and their analogs. 1. Thiazolopyrimidopyrimidines, Recommanded Product: 1-Ethyl-2-methylquinolin-1-ium iodide, the publication is Khimiya Geterotsiklicheskikh Soedinenii (1992), 692-7, database is CAplus.

3-Aminothiazolo[3,2-a] pyrimidinium salts (I; R = H, OMe) were prepared in 47-71% yield by treating 6-substituted 2-mercaptopyrimidines with Ph α-cyanobenzylbenzosulfonate, α-bromopropionitrile, or Et bromocyanoacetate and heating. Vilsmeier reaction (DMF, POCl₃) of the pyrimidinium salts led to Me formylation in the 5 position and to formation of a new heterocyclic system (thiazolopyrimidopyrimidine). The formyl-substituted thiazolopyrimidopyrimidines were separated as crystalline dark-blue substances having in addition to intense UV absorption bands a less intense, broad absorption band at ∼600 nm with well expressed vibrational structure. The thiazolopyrimidopyrimidines were treated with N-containing heterocyclic quaternary salts or nucleophilic agents (malonodinitrile) to give polymethine dyes.

Khimiya Geterotsiklicheskikh Soedinenii published new progress about 606-55-3. 606-55-3 belongs to iodides-buliding-blocks, auxiliary class Quinoline,Salt, name is 1-Ethyl-2-methylquinolin-1-ium iodide, and the molecular formula is C12H14IN, Recommanded Product: 1-Ethyl-2-methylquinolin-1-ium iodide.

Referemce:
https://en.wikipedia.org/wiki/Iodide,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Hassel, O. published the artcileStructure of the 1:1 compound pyridine-iodomonochloride, Formula: C5H5ClIN, the publication is Acta Chemica Scandinavica (1956), 696-8, database is CAplus.

cf. C.A. 48, 12115f; 50, 12592f. Pyridine-iodomonochloride, yellow monoclinic needles, m. 132°, space group P2₁/c, has parameters: a 4.25, b 12.29, c 14.07 A., β 94.4°, and bond distances I-Cl 2.51, N-Cl 2.26 A. Experiments show that the I, Cl, and N atoms are at least very nearly on a straight line, and suggest that the C atom opposite the N atom is also on this line, but do not appear to strengthen the suggestion that the “outer” halogen atom attains a strong neg. charge. Previous structure studies of ether-halogen addition compounds are compared with these on N compounds The strong interaction between the O or N atom and the nearest halogen atom is evident from the short separation between these atoms, this effect being greatest in the case of N. It is probable that electrons associated with the atoms forming the O-halogen or N-halogen bond are partially promoted to d orbitals.

Acta Chemica Scandinavica published new progress about 6443-90-9. 6443-90-9 belongs to iodides-buliding-blocks, auxiliary class Pyridines, name is Pyridine Iodochloride complex, and the molecular formula is C5H5ClIN, Formula: C5H5ClIN.

Referemce:
https://en.wikipedia.org/wiki/Iodide,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Poyac, Ludivine published the artcileSynthesis, Characterization, and Encapsulation Properties of Rigid and Flexible Porphyrin Cages Assembled from N-Heterocyclic Carbene-Metal Bonds, Safety of 1-Iodohexane, the publication is Inorganic Chemistry (2021), 60(24), 19009-19021, database is CAplus and MEDLINE.

Four porphyrins equipped with imidazolium rings on the para positions of their meso aryl groups were prepared and used as tetrakis(N-heterocyclic carbene) (NHC) precursors for the synthesis of porphyrin cages assembled from eight NHC-M bonds (M = Ag⁺ or Au⁺). The conformation of the obtained porphyrin cages in solution and their encapsulation properties strongly depend on the structure of the spacer -(CH₂)_n– (n = 0 or 1) between meso aryl groups and peripheral NHC ligands. In the absence of methylene groups (n = 0), porphyrin cages are rather rigid and the short porphyrin-porphyrin distance prevents the encapsulation of guest mols. like 1,4-diazabicyclo[2.2.2]octane (DABCO). By contrast, the presence of methylene functions (n = 1) between meso aryl groups and peripheral NHCs offers addnl. flexibility to the system, allowing the inner space between the two porphyrins to expand enough to encapsulate guest mols. like water mols. or DABCO. The peripheral NHC-wingtip groups also play a significant role in the encapsulation properties of the porphyrin cages.

Inorganic Chemistry published new progress about 638-45-9. 638-45-9 belongs to iodides-buliding-blocks, auxiliary class Iodide,Aliphatic hydrocarbon chain, name is 1-Iodohexane, and the molecular formula is C6H13I, Safety of 1-Iodohexane.

Referemce:
https://en.wikipedia.org/wiki/Iodide,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Shanazarov, K. S. published the artcilePreparation of esters of pelvirinic acid [3,5-diiodo-4-oxo-1(4H)-pyridineacetic acid], Application In Synthesis of 101-29-1, the publication is Khimiko-Farmatsevticheskii Zhurnal (1968), 2(4), 40-2, database is CAplus.

Esterification of 3,5-diiodo-4-oxo-1(4H)-pyridineacetic acid (I) was accomplished in the presence of KU 2 catalyst. The following esters were prepared (% yield and m.p. given): Pr, 94.8, 188-9°; iso-Pr, 91.2, 214-15°; and Bu, 87, 194°.

Khimiko-Farmatsevticheskii Zhurnal published new progress about 101-29-1. 101-29-1 belongs to iodides-buliding-blocks, auxiliary class Pyridine,Iodide,Carboxylic acid,Ketone, name is 2-(3,5-Diiodo-4-oxopyridin-1(4H)-yl)acetic acid, and the molecular formula is C14H20BNO4, Application In Synthesis of 101-29-1.

Referemce:
https://en.wikipedia.org/wiki/Iodide,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Druzhinin, S. I. published the artcileExcited state relaxation processes of crowned styryl dyes and their metal complexes, Related Products of iodides-buliding-blocks, the publication is Proceedings – Indian Academy of Sciences, Chemical Sciences (1995), 107(6), 721-7, database is CAplus.

The fluorescence of novel crown ether styryl dyes and their complexes with sodium cation was studied. The fluorescence quantum yield of crown ether styryl dyes is higher than that of dyes not containing crown ethers. While absorption and fluorescence spectra of a styryl dye are shifted to high frequency regions, its fluorescence quantum yield in the absence of photoisomerization is practically unchanged, and the rate constant of its fluorescence quenching rises as it forms a complex with the metal ion. The relaxation processes of photoisomerization and recoordination are considered. The adiabatic change of metal ion coordination in the crown ether may proceed in the excited state. The trans-cis photoisomerization of styryl dyes and their metal complexes is a barrierless reaction.

Proceedings – Indian Academy of Sciences, Chemical Sciences published new progress about 606-55-3. 606-55-3 belongs to iodides-buliding-blocks, auxiliary class Quinoline,Salt, name is 1-Ethyl-2-methylquinolin-1-ium iodide, and the molecular formula is C12H14IN, Related Products of iodides-buliding-blocks.

Referemce:
https://en.wikipedia.org/wiki/Iodide,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Landauer, S. R. published the artcileThe organic chemistry of phosphorus. I. Some new methods for the preparation of alkyl halides, Recommanded Product: Ethyl 2-Iodopropionate, the publication is Journal of the Chemical Society (1953), 2224-34, database is CAplus.

cf. C.A. 45, 9456e. (MeO)₃P (I) (0.1 mol) refluxed 30 min. at 100° with MeI and the product distilled, gave MePO(OMe)₂ (II); with molar ratios of I:MeI = 1:1, 2:1, 10:1, and 100:1, the yields of II were 90, 88, 93, and 80%, resp. I (6.2 g.) and 0.06 g. Me₂SO₄ refluxed 15 min. at 100° gave 8% recovered I and 81% II, b₁₂ 66°. (PhO)₃P (III) (31 g.) and 21 g. MeI refluxed 36 h. with exclusion of H₂O, the mixture treated with anhydrous ether, and the solid washed with anhydrous ether, dried, and weighed in vacuo, gave 42 g. (PhO)₃PMeI (IV), which was stored under ether, dried, and weighed in vacuo before use; IV taken up in Me₂CO and precipitated with anhydrous ether gave pure IV, m. 146°. IV (7.95 g.) in 30 mL. absolute EtOH and 150 mL. saturated alc. AgNO₃ gave after 3, 6, 10, 20, 80, 150, and 1440 min. 67, 73, 76, 79, 86, 92, and 100%, resp., total yield of AgI (204.5 mg. IV gave 09.6% AgI after 3 min.). IV (21 g.) shaken several min. with 35 mL. absolute EtOH and the solution distilled, gave 62% EtI, b. 72° (PhNEtMe₂I, m. 136-7°), PhOH, and 91% MePO(OPh)₂ (V), m. 35-6°. In a 2nd experiment in which the mixture was distilled at 0.5 mm., 66% EtI was collected in a trap at -80°; the residue, washed with 2N NaOH gave 86% V; the alk. washings gave with acid 96% PhOH. Iodides were similarly prepared from IV and the appropriate alc., cooling being necessary with reactive alcs., warming with less reactive alcs.; the iodide was isolated by distillation of the reaction mixture in vacuo, with the iodide collected at -80° in a trap (when the b.p. was much lower that of PhOH), by distillation with PhOH in vacuo and separation of the PhOH with cold dilute NaOH, or by removal of the PhOH from the reaction mixture with dilute NaOH and distillation The method is satisfactory with primary, secondary, tertiary (76% yield of Me₃CI), and unsaturated alcs. (83% yield of MeCH:CHCH₂I, b_40-5 55-6°), glycols (95% yield of CH₂(CH₂I)₂, b_0.5 50-1°, n²¹_D 1.6420), and Et lactate (92% yield of MeCHICO₂Et, b₈ 65-6°, n^20.5_D 1.5000), giving 60-95% yields. Cholesterol (9.5 g.) mixed with 12 g. IV, 10 mL. MeI added, the mixture refluxed 1 h. at 50-60°, kept overnight, extracted with 100 mL. petr. ether (b. 40-60°), the extract evaporated, the residue treated with 100 mL. H₂O, the insoluble part washed with Me₂CO, taken up in 200 mL. hot Me₂CO, cooled, and the solution decanted from the oil and cooled at 2° gave 30% cholesteryl iodide, m. 105° (from EtOAc), [α]^21.2_D -12.7° (CHCl₃). III (34 g.) and 13 g. PhCH₂Cl heated 60 h. at 170-5° and the mixture washed with petr. ether (b. 40-60°), gave 25 g. oily (PhO)₃P(CH₂ph)Cl (VI). VI (10 g.) kept overnight at room temperature with 2 g. (+)-2-octanol, α^21.4_D 7.72°, and the mixture distilled gave 79% (-)-2-chloroöctane, b₁₃ 60°, n²⁰_D 1.4275, [α]^22.4_D -24.72°. PCl₃ (23 g.) added (20 min.) to 54 g. stirred, cooled PhCH₂OH, 61 g. PhNMe₂, and 100 mL. absolute ether, the mixture filtered, and the filtrate distilled twice gave 8 g. (PhCH₂O)₂P(O)H, b_0.05 145-60°, 10 g. mixture, b_0.05 160-80°, and 18 g. (PhCH₂O)₃P (VII), b_0.05 180-95°, m. 52° (from petr. ether). VII and MeI heated 30 h. at 100° gave no addition product; heated 3 h. at 150°, VII and MeI gave PhCH₂I. Summaries are given for the preparation of 12 iodides, 4 bromides, and 5 chlorides directly from III, the halide (MeI, PhCH₂Br, or PhCH₂Cl), and the alc. III (68 g.), 40 g. BuI, and 6.4 g. absolute MeOH heated 24 h. at 165-85°, with the MeI fractionated off continuously, gave 16 g. MeI, b. 42-3°, n²⁰_D 1.5290. MeBr passed slowly (through a sintered glass plate) into a mixture of 50 g. III and 11 g. BuOH heated 12 h. (155-35°), the mixture distilled, and the product collected at -80°, gave 63% BuBr, b. 101.5°, n²⁰_D 1.4400. (EtO)₃P (16.6 g.), 14.2 g. MeI, and 22.2 g. BuOH refluxed 1 h. gave 64% impure EtI and 36% BuI, b. 110-30°, n²⁰_D 1.4935. Dry HCl passed (1.5 h.) into equimol. amounts of III and BuOH gave 76% BuCl, b. 77-9°, n¹⁷_D 1.4025; similarly (-)-2-octanol (kept overnight with III before HCl was added for 1 h.) gave 44% (+)-2-chloroöctane, b_8-10 53-6°, [α]^22.2_D 18.8°; 2 g. cholesterol, 5 g. III, and HCl (30 min. addition), treated with 20 mL. Me₂CO, gave 2.2 g. cholesteryl chloride, m. 95° (from EtOAc), [α]²⁰_D -33.3° (CHCl₃). III (34 g.), 7.4 g. BuOH, and 6 g. NH₄Cl refluxed 84 h. at 140° gave 63% BuCl, b. 77-8°, n²²_D 1.4015. Similarly III and BuOH with 6 g. NaCl (heated 120 h. at 170-80°) gave 16% BuCl; with 9.6 g. LiBr (heated 64 h. at 140°), 40% BuBr; with 16.5 g. NaI (heated 64 h. at 160-70°), 18.5% BuI. IV (7 g.), 1.5 g. absolute EtOH, and 3 g. PhNMe₂ warmed 15 min. on a steam bath and diluted with ether gave 3.8 g. PhNMe₂EtI, m. 131° (from EtOH). III (68 g.) and 14.8 g. BuOH heated 16 h. at 100° gave 18.5 g., b₁₀ 60-80° (mainly PhOH), 7.5 g., b₁₀ 80-120°, n²⁵_D 1.4580 [mainly (BuO)₃P], 7.8 g. mixture, b₁₀ 120-40°, n²⁵_D -1.4840, of (BuO)₃P and (BuO)₂P(O)Ph, 9 g., b₁₀ 140-70°, n²⁵_D 1.5302, [mainly BuOP(OPh)₂ (VIII)], 4.1 g., b₁₀ 170-80°, n²⁵_D 1.5819, (mixture of VIII and III), and 28 g. residue, n²⁵_D 1.5815. III (68 g.) and 14.8 g. BuOH kept 30 min. at room temperature and distilled gave 18 g. PhOH and a mixture of phosphites which, refluxed 3 h. with 13 g. MeI, gave 13 g. BuI, n²³_D 1.4990; the residue heated 24 h. with 28 g. MeI gave 15.1 g. addnl. BuI, b. 125-31°, n²²_D 1.4980. IV (23 g.) and 3 g. V refluxed 1 h. and distilled gave 5 g. MeI, b. 42-4°, n²⁰_D 1.5055. IV (5 g.) and 2.5 g. (BuO)₃P mixed to give a solution and distilled gave 1.8 g. BuI, b. 125-32°, n²³_D 1.4970. Et(O)PCl₂ (IX) (147 g., b. 117-18°) and 500 mL. absolute ether cooled in a freezing mixture and treated portion wise with NaOMe (from 46 g. powd. Na and 64 g. MeOH) in 500 mL. ether, the mixture kept 1 h. at room temperature, filtered, the filtrate distilled, and the product fractionated gave 56 g. EtOP(OMe)₂ (X), b. 124-7°, equivalent 138.0 (equivalents were determined by hydrolysis of about 150 mg. alkyl phosphite 1 h. at 100° with 5 mL. 70% alc. NaOH, dilution with 0.1N HCl, and titration of the excess alkali with bromophenol blue; the authors found that equivalents gave a better criterion of purity than elemental anal.). X (27.6 g.) refluxed 1 h. with 28.4 g. MeI and fractionated gave 27.5 g. MeI and 27 g. EtO(MeO)P(O)Me, b₁₅ 74-5°, equivalent 137.8. X (13.8 g.), 2 g. H₂O, and 10 mL. Me₂CO kept 1 h. and distilled gave P-containing fractions, 1.3 g., b_15-17 65-73°, 9 g. EtO(MeO)(HO)P, b_15-17 73-5°, equivalent 124.0, and 1.3 g., b_15-17 75-7°. Absolute MeOH (32 g.) and 121 g. PhNMe₂ added (1 h.) to 137 g. PCl₃ cooled, stirred in 1 l. absolute ether, 92 g. absolute EtOH, and 242 g. PhNMe₂ then added (2 h.), the mixture diluted with 500 mL. ether, filtered, the filtrate distilled, and the fraction, b_10-15 50-90°, fractionated gave 35 g. (EtO)₂POMe (XI), b. 136-9°, equivalent 152.6. XI (10 g.) and 8.5 g. MeI refluxed 30 min. and distilled gave 6.8 g. MeI and 6 g. (EtO)₂P(O)Me, b. 190-2°, n²³_D 1.4110, equivalent 152.0. XI (10 g.), 1.5 g. H₂O, and 10 mL. Me₂CO gave 5.3 g. (EtO)₂POH, b₈ 65-6°, n²¹_D 1.4070, equivalent 137.2. iso-PrOH (120 g.) and 242 g. PhNMe₂ added (80 min.) to cold 130 g. IX in 500 mL. absolute ether, the mixture stirred 30 min. and filtered, and the filtrate fractionated gave 97 g. (iso-PrO)₂POEt (XII), b₁₀ 69-71°, equivalent 192.1. XII (19.5 g.) and 14.2 g. MeI refluxed 30 min. at 100° and distilled gave 12 g. EtI, b. 71-3°, and 17 g. (iso-PrO)₂P(O)Me, b₅ 7-5-6°, n²⁰_D 1.4158. XII (19.5 g.), 2 g. H₂O, and 10 mL. Me₂CO refluxed 14 h. and distilled gave 12.5 g. (iso-PrO)₂P.OH, b₁₀ 89-90°, equivalent 159.3. The mechanism for the formation of alkyl halides is discussed. Halides included in tables: EtI, iso-PrI, n-BuI, sec-BuI, tert-BuI, (+)- and (-)-2-iodoöctane, cyclohexyl iodide, CH₂:CHCH₂I, MeCH:CHCH₂Cl, PhCH₂I, PhCH₂CH₂I, PhCHIMe, CH₂(CH₂I)₂, MeCHICO₂Et, Me₂C(CH₂I)₂, and Me₃CCH₂I; BuBr, CH₂:CHCH₂Br, CH₂(CH₂2Br)₂, MeCHBrCO₂Et; BuCl, CH₂:CHCH₂Cl, CH₂(CH₂Cl)₂, MeCHClCO₂Et, and n-C₆H₁₃Cl.

Journal of the Chemical Society published new progress about 31253-08-4. 31253-08-4 belongs to iodides-buliding-blocks, auxiliary class Iodide,Ester, name is Ethyl 2-Iodopropionate, and the molecular formula is C5H9IO2, Recommanded Product: Ethyl 2-Iodopropionate.

Referemce:
https://en.wikipedia.org/wiki/Iodide,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Popov, Alexander I. published the artcileThe chemistry of halogens and of polyhalides. XI. Molecular complexes of pyridine, 2-picoline, and 2,6-lutidine with iodine and iodine halides, Recommanded Product: Pyridine Iodochloride complex, the publication is Journal of the American Chemical Society (1957), 4622-5, database is CAplus.

cf. C.A. 51, 7931a. Crystalline addition compounds of 2-picoline, 2,6-lutidine, and pyridine were prepared with ICI and IBr. The dissociation constants of these 6 compounds and of the 3 mol. complexes, amine-I₂, were determined spectrophotometrically in CCl₄ solutions The order of stability for the halogen series was ICI > IBr > I₂, in agreement with the acidic strength of the halogens. The order of stability for the amine series was 2-picoline > pyridine > 2,6-lutidine. The low stability of 2,6-lutidine complexes is ascribed to steric effects. The absorption spectra of acetonitrile solutions of the 6 addition compounds had maximum at either the 227 mμ peak of ICl₂^–, or the 256 mμ peak of IBr₂^–, indicating an ionic dissociation in this polar solvent, as opposed to mol. dissociation in nonpolar CCl₄.

Journal of the American Chemical Society published new progress about 6443-90-9. 6443-90-9 belongs to iodides-buliding-blocks, auxiliary class Pyridines, name is Pyridine Iodochloride complex, and the molecular formula is C5H5ClIN, Recommanded Product: Pyridine Iodochloride complex.

Referemce:
https://en.wikipedia.org/wiki/Iodide,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com