Category: iodides-buliding-blocks

Xiao, Shouhua published the artcileInfluences of grafting on aromatic compounds in muskmelon by solid phase microextraction with GC-MS, Application In Synthesis of 101-29-1, the publication is Acta Horticulturae (2010), 365-375, database is CAplus.

There has been an increase in popularity of grafting technique on muskmelon in agricultural production because grafting of melon increased its disease resistance to fusarium wilt, but melon’s (Cucumis melo L.) quality has been more serious inferior than its own-rooted melon. The volatiles substance plays an important role in melon fruit quality. We have found very little reports in literature for melon grafting varieties and using solid-phase microextraction (SPME). The objective of this experiment was to identify volatile and semivolatile compounds in two melon cultivars ‘Lu135’ and ‘Lu7475’, using solid-phase microextraction (SPME) with gas chromatog.-mass spectrometry (GC-MS). Fully ripe melon was squeezed through miracloth to produce rapid juice extracts for immediate headspace SPME GC-MS. One hundred forty two volatile compounds were separated in ripe muskmelon, they consisted of 56 esters, 27 alcs., 3 aldehydes, 17 ketones, 21 alkenes and 18 other substances. Among these compounds, types of esters and alcs. were the important aroma components accounting for over 74.75-93.46% of total peak area. The most abundant compounds in two cultivars were acetic acid, phenylmethyl ester (21.65-36.43%), acetic acid, hexyl ester (6.05-12.95%), Et acetate (2.89-9.94%), 1-butanol, 2-methyl-, acetate (5.84-7.82%). The total aromatic compounds and characteristic aromatic esters contents decreased in grafted melons than the own-rooted melon. The delightful fruit aroma in grafting melon was lower and thinner in comparison to own-rooted. Meanwhile, the aroma components of melon were altered because of grafting in adopting of melon. However, the effect of grafting on aroma components was different between two varieties. The total esters content and category in ‘Lu135’ was obviously lower in grafting melons than own-rooted and it had little chance on ‘Lu7475’.

Acta Horticulturae published new progress about 101-29-1. 101-29-1 belongs to iodides-buliding-blocks, auxiliary class Pyridine,Iodide,Carboxylic acid,Ketone, name is 2-(3,5-Diiodo-4-oxopyridin-1(4H)-yl)acetic acid, and the molecular formula is C5H10N2OS, Application In Synthesis of 101-29-1.

Referemce:
https://en.wikipedia.org/wiki/Iodide,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Zhang, Linfeng published the artcileMicrowave-Assisted Nickel-Catalyzed Rapid Reductive Coupling of Ethyl 3-iodopropionate to Adipic Acid, Recommanded Product: 1-Iodohexane, the publication is Catalysis Letters (2021), 151(8), 2339-2345, database is CAplus.

3-Iodopropionic acid (3-IPA) can be efficiently synthesized from the glycerol derivative glyceric acid (GA), which is a potential biomaterial-based platform mol. In this report, Et 3-iodopropionate was rapidly dimerized to di-Et adipate in a microwave reactor using NiCl₂.6H₂O as a catalyst, co-catalyzed by Mn and the 1, 10-Phenanthroline monohydrate ligand. Under the optimum reaction conditions, di-Et adipate can be obtained with 84% yield at 90°C in just 5 min. Di-Et adipate was hydrolyzed to obtain the adipic acid (AA) in 89% yield with an acid catalyst. AA is an important chem. and a monomer for producing a wide range of high-performance polymeric substances. This rapid coupling method is also applicable to other alkyl halides.

Catalysis Letters published new progress about 638-45-9. 638-45-9 belongs to iodides-buliding-blocks, auxiliary class Iodide,Aliphatic hydrocarbon chain, name is 1-Iodohexane, and the molecular formula is C18H12ClNO, Recommanded Product: 1-Iodohexane.

Referemce:
https://en.wikipedia.org/wiki/Iodide,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Xie, Li published the artcileDetermination of hypochlorite and bisulfite in water by bifunctional colorimetric sensor based on octupolar conjugated merocyanine dyes, Quality Control of 638-45-9, the publication is Microchemical Journal (2022), 172(Part_A), 106931, database is CAplus.

In this study, we developed a bifunctional colorimetric fluorescent sensor based on three merocyanine structures for the detection of hypochlorite (ClO^–) and bisulfite (HSO₃^–). In MeOH solution and under special conditions, this sensor shows high selectivity on fluorescence and UV-Vis spectra for the detection of ClO^– and HSO₃^–, resp. The sensor solution exhibits a strong red fluorescence emission at 638 nm, which was quenched and the blue color turned to purple pink rapidly upon the addition of ClO^–. The mechanism of the detection of ClO^– was confirmed via ESI-MS that the C=C groups were induced to produce ethylene oxide and ethylene glycol derivatives by hypochlorite. The fluorescence emission at 638 nm in the concentration range of ClO^– from 0 to 24 μM showed a good linear relationship (R² = 0.9919), and the LOD of the sensor for ClO^– was 0.42 μM. Interestingly, the sensor can also detect HSO₃^– in acid condition (pH less than 7.4). The blue shift of UV-Vis spectra of the solution of sensor were observed after addition of HSO₃^– and irradiation with visible light for about 4 min. The HSO₃^– concentration showed a good linear relationship (R² = 0.9987) at 275 nm in the range of 12-42 μM, and thus its LOD was calculated to be 1.14 μM. Finally, the sensor has important value for detecting ClO^– and HSO₃^– in tap water and lake water.

Microchemical Journal published new progress about 638-45-9. 638-45-9 belongs to iodides-buliding-blocks, auxiliary class Iodide,Aliphatic hydrocarbon chain, name is 1-Iodohexane, and the molecular formula is C9H5ClO2, Quality Control of 638-45-9.

Referemce:
https://en.wikipedia.org/wiki/Iodide,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Han, Qian published the artcileA redox-switchable colorimetric probe for “Naked-Eye” detection of hypochlorous acid and glutathione, Synthetic Route of 606-55-3, the publication is Molecules (2019), 24(13), 2455, database is CAplus and MEDLINE.

We report the development of a new colorimetric probe (L-ol) for investigations of the redox process regulated by hypochlorous acid (HOCl) and glutathione (GSH). The HOCl/GSH redox-switching cycle process was investigated in detail by UV-visible absorption spectroscopy, colorimetric anal. assay and high-resolution mass spectrometry (HRMS). The switchable absorbance responses were attributed to the HOCl-induced oxidation of the p-methoxyphenol unit to the benzoquinone derivative (L-one) and sequential reduction of L-one to hydroquinone (L-ol’) by GSH. In phosphate-buffered saline (PBS) buffer, the absorbance of L-ol at 619 nm underwent a remarkable bathochromic-shift, accompanied by a color change from pale yellow to blue in the presence of HOCl. With further addition of GSH, the absorbance of L-one exclusively recovered to the original level. Meanwhile, the blue-colored solution returned to the naive pale yellow color in the presence of GSH. The detection limits for HOCl and GSH were calculated to be 6.3 and 96 nM according to the IUPAC criteria. Furthermore, L-ol-loaded chromatog. plates have been prepared and successfully applied to visualize and quant. analyze HOCl in several natural waters.

Molecules published new progress about 606-55-3. 606-55-3 belongs to iodides-buliding-blocks, auxiliary class Quinoline,Salt, name is 1-Ethyl-2-methylquinolin-1-ium iodide, and the molecular formula is C12H14IN, Synthetic Route of 606-55-3.

Referemce:
https://en.wikipedia.org/wiki/Iodide,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Xiang, Jian-nan published the artcileSynthesis of diheterocyclic compounds on 1,3,4-oxadiazole and 1,2,4-triazole, Product Details of C7H7IN2O, the publication is Hunan Daxue Xuebao, Ziran Kexueban (2009), 36(3), 63-66, database is CAplus.

A method for the synthesis of the title compounds [i.e., 1,3,4-oxadiazole-2-thione and 1,2,4-triazole-3-thione derivatives] is reported here. Said compounds were prepared by a coupling reaction of (4-iodophenyl)(fluoroalkyl)-1,2,4-triazole-3-thione derivatives and (4-iodophenyl)(fluoroalkyl)-1,3,4-oxadiazole-2-thione derivatives with (ethynyl)(fluoroalkyl)-1,2,4-triazole-3-thione. This approach is based mol. design technol., such as activity substructure connection. Structures of the target compounds were determined by NMR, ¹⁹F-NMR, IR, MS, elemental anal.

Hunan Daxue Xuebao, Ziran Kexueban published new progress about 39115-95-2. 39115-95-2 belongs to iodides-buliding-blocks, auxiliary class Iodide,Hydrazine,Amine,Benzene,Hydrazide,Amide, name is 4-Iodobenzohydrazide, and the molecular formula is C39H35N5O8, Product Details of C7H7IN2O.

Referemce:
https://en.wikipedia.org/wiki/Iodide,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Peng, Ye-Dong published the artcileFerrocene-isocoumarin conjugated molecules: synthesis, structural characterization, electronic properties, and DFT-TDDFT computational study, Related Products of iodides-buliding-blocks, the publication is Dalton Transactions (2015), 44(32), 14465-14474, database is CAplus and MEDLINE.

Two ferrocene-isocoumarin conjugated mols., Me 3-ferrocenyl-1-oxo-1H-isochromene-6-carboxylate (Fc-Icm) and 3,8-bisferrocenylpyrano[3,4-g]isochromene-1,6-dione (BFc–PIcm), were synthesized through the acid-prompted regioselective oxidative cyclization from di-Me 2-(ferrocenylethynyl)terephthalate (Fc-TP) and di-Me 2,5-bis(ferrocenylethynyl)terephthalate (BFc-TP), resp. Single-crystal x-ray diffraction, together with the d. functional theory (DFT) calculations, shows that the ferrocene-isocoumarin conjugated compounds display better coplanarity than the corresponding ferrocenylethynyl terephthalates. All the compounds exhibit characteristic MLCT, ICT and π-π^* transitions in the UV-visible range in solution, and Fc-Icm and BFc-PIcm show higher oscillator strength of the absorption than Fc-TP and BFc-TP, which are verified by time-dependent DFT (TDDFT) theor. calculations The electrochem. properties were studied by cyclic voltammetry (CV), which are also in accord with the theor. calculations

Dalton Transactions published new progress about 165534-79-2. 165534-79-2 belongs to iodides-buliding-blocks, auxiliary class Iodide,Benzene,Ester, name is Dimethyl 2-iodoterephthalate, and the molecular formula is C10H9IO4, Related Products of iodides-buliding-blocks.

Referemce:
https://en.wikipedia.org/wiki/Iodide,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Jiang, Baifeng published the artcileOne-pot synthesis of dihydrobenzo[4,5][1,3]oxazino[2,3-a]isoquinolines via a silver(I)-catalyzed cascade approach, Application of (2-Amino-5-iodophenyl)methanol, the publication is Molecules (2013), 814-831, database is CAplus and MEDLINE.

An efficient approach for the synthesis of biol. interesting fused tetracyclic isoquinoline derivatives in high yield and with a broad substrate scope was developed. The strategy features an AgNO₃ catalyzed one-pot cascade process involving formation of two new C-N bonds and one new C-O bond. The title compounds thus formed included 12-phenyl-4bH,6H-isoquino[2,1-a][3,1]benzoxazine (I) and related substances, such as a pyridooxazinoisoquinoline derivative (II). The synthesis of the target compounds was achieved using 2-(2-phenylethynyl)benzaldehyde, 5-fluoro-2-(2-phenylethynyl)benzaldehyde, 2-(1-octyn-1-yl)benzaldehyde, 2-aminobenzenemethanol, 3-amino-2-naphthalenemethanol, 2-amino-3-pyridinemethanol (amino arenemethanol derivatives) as starting materials.

Molecules published new progress about 53279-83-7. 53279-83-7 belongs to iodides-buliding-blocks, auxiliary class Iodide,Amine,Benzene,Alcohol, name is (2-Amino-5-iodophenyl)methanol, and the molecular formula is C7H8INO, Application of (2-Amino-5-iodophenyl)methanol.

Referemce:
https://en.wikipedia.org/wiki/Iodide,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Tian, Chengze published the artcileDiscovery of cinnoline derivatives as potent PI3K inhibitors with antiproliferative activity, Quality Control of 638-45-9, the publication is Bioorganic & Medicinal Chemistry Letters (2021), 128271, database is CAplus and MEDLINE.

Cinnoline is a potential pharmacophore which has rarely been reported for uses as PI3K inhibitors. In this study, a series of cinnoline derivatives were developed as PI3K inhibitors and evaluated for enzymic and cellular activities. Most compounds displayed nanomolar inhibitory activities against PI3Ks, among which 25 displayed high LLE and micromolar inhibitory potency against three human tumor cell lines (IC₅₀ = 0.264μM, 2.04μM, 1.14μM).

Bioorganic & Medicinal Chemistry Letters published new progress about 638-45-9. 638-45-9 belongs to iodides-buliding-blocks, auxiliary class Iodide,Aliphatic hydrocarbon chain, name is 1-Iodohexane, and the molecular formula is C18H34N4O5S, Quality Control of 638-45-9.

Referemce:
https://en.wikipedia.org/wiki/Iodide,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Zhang, Zhen-Qi published the artcileCopper-Catalyzed/Promoted Cross-coupling of gem-Diborylalkanes with Nonactivated Primary Alkyl Halides: An Alternative Route to Alkylboronic Esters, Synthetic Route of 161370-66-7, the publication is Organic Letters (2014), 16(24), 6342-6345, database is CAplus and MEDLINE.

The first copper-catalyzed/promoted sp³-C Suzuki-Miyaura coupling reaction of gem-diborylalkanes with nonactivated electrophilic reagents is reported. Not only 1,1-diborylalkanes but also some other gem-diborylalkanes can be coupled with nonactivated primary alkyl halides, offering a new method for sp³C-sp³C bond formation and, simultaneously, providing a new strategy for the synthesis of alkylboronic esters.

Organic Letters published new progress about 161370-66-7. 161370-66-7 belongs to iodides-buliding-blocks, auxiliary class Chiral,Iodide,Amine,Aliphatic hydrocarbon chain,Ester,Amide, name is (S)-tert-Butyl 2-((tert-butoxycarbonyl)amino)-4-iodobutanoate, and the molecular formula is C6H8BNO3, Synthetic Route of 161370-66-7.

Referemce:
https://en.wikipedia.org/wiki/Iodide,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Li, Hong-Liang published the artcilePalladium-Catalyzed Enantioselective C(sp³)-H Arylation of 2-Propyl Azaaryls Enabled by an Amino Acid Ligand, Product Details of C6H13I, the publication is Organic Letters (2022), 24(6), 1286-1291, database is CAplus and MEDLINE.

A palladium(II)-catalyzed enantioselective arylation of unbiased secondary C(sp3)-H bonds was developed. The enantioselectivity was controlled by the combination of a pyridyl or isoquinolinyl directing group and an amino acid, N-Boc-2-pentyl proline. A variety of 2-Pr azaaryls and biaryl iodides were employed to provide arylated products in moderate to good yields (up to 82%) with high enantioselectivities (up to 93:7 er). This reaction is a rare example of an amino-acid-enabled enantioselective acyclic methylene C(sp3)-H arylation. Furthermore, the reaction proceeded with high enantioselectivity even on a gram scale, and the product was transformed to a 5,6,7,8-tetrahydroisoquinoline bioactive mol. Kinetic isotope effect (KIE) experiments indicated that C-H activation is the rate-determining step for the enantioselective C(sp3)-H arylation.

Organic Letters published new progress about 638-45-9. 638-45-9 belongs to iodides-buliding-blocks, auxiliary class Iodide,Aliphatic hydrocarbon chain, name is 1-Iodohexane, and the molecular formula is C6H13I, Product Details of C6H13I.

Referemce:
https://en.wikipedia.org/wiki/Iodide,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com