Ramesh, Karu et al. published their research in European Journal of Organic Chemistry in 2019 | CAS: 207115-22-8

4-Bromo-2-iodophenol (cas: 207115-22-8) belongs to iodide derivatives. Organic iodides can be alkyl, alkenyl, or alkynyl, and all of them are very reactive toward with many kinds of nucleophiles. A typical method for synthesis of aromatic iodides is diazotization of primary aromatic amines followed by treatment of potassium iodide. Aliphatic alcohols are converted to alkyl iodides by treating with hydrogen iodide.Safety of 4-Bromo-2-iodophenol

Microwave-Assisted Domino Heck Cyclization and Phosphorylation: Synthesis of Phosphorus Containing Heterocycles was written by Ramesh, Karu;Satyanarayana, Gedu. And the article was included in European Journal of Organic Chemistry in 2019.Safety of 4-Bromo-2-iodophenol This article mentions the following:

A domino [Pd]-catalyzed intramol. Heck cyclization of 2-iodophenyl allyl ethers, esters and amides followed by intermol. phosphorylation with secondary phosphine oxides HP(O)Ar2, for the construction of 3-phosphinylmethyl 2,3-dihydrobenzofurans is presented. Notably, the process is accelerated by microwave heating conditions and enabled the construction of C-C and C-P bonds in short reaction times. In the experiment, the researchers used many compounds, for example, 4-Bromo-2-iodophenol (cas: 207115-22-8Safety of 4-Bromo-2-iodophenol).

4-Bromo-2-iodophenol (cas: 207115-22-8) belongs to iodide derivatives. Organic iodides can be alkyl, alkenyl, or alkynyl, and all of them are very reactive toward with many kinds of nucleophiles. A typical method for synthesis of aromatic iodides is diazotization of primary aromatic amines followed by treatment of potassium iodide. Aliphatic alcohols are converted to alkyl iodides by treating with hydrogen iodide.Safety of 4-Bromo-2-iodophenol

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Abraham, Raymond J. et al. published their research in Physical Chemistry Chemical Physics in 2016 | CAS: 64248-57-3

1,2-Difluoro-3-iodobenzene (cas: 64248-57-3) belongs to iodide derivatives. Organic iodides can be alkyl, alkenyl, or alkynyl, and all of them are very reactive toward with many kinds of nucleophiles. The C–I bond is the weakest of the carbon–halogen bonds. These bond strengths correlate with the electronegativity of the halogen, decreasing in the order F > Cl > Br > I. This periodic order also follows the atomic radius of halogens and the length of the carbon-halogen bond.Recommanded Product: 64248-57-3

A re-investigation of 4JFF and 5JFF nuclear spin-spin couplings in substituted benzenes, a novel conformational tool was written by Abraham, Raymond J.;Cooper, M. Ashley. And the article was included in Physical Chemistry Chemical Physics in 2016.Recommanded Product: 64248-57-3 This article mentions the following:

A theor. anal. of the 4JFF and 5JFF couplings in fluorobenzenes separates the σ and π components of the substituent coefficients The π bond mechanism is dominant but the σ bond mechanism must be included to give accurate values of the couplings. For monosubstituted difluorobenzenes the 4JFF and 5JFF couplings can be predicted from the calculated π densities by linear equations. The use of additive substituent effects allows the prediction of the meta4JFF couplings for multisubstituted compounds The π dependence of the 4JFF coupling in 2,6-difluorobenzenes provides a novel and simple method of determining the torsional angle of the C1 substituent and the benzene ring for non-sym. functional groups (acetyl, carboxymethyl, dimethylamino, amide, nitro etc.). This could be used to determine the geometries of such mols. in biol. systems. The π dependence of the 4JFF coupling is also of importance in the charged species of 2,6-difluoroanilinium (4JFF 2.1 Hz) and 2,6-difluoro-N,N,N-trimethylanilinium (4JFF 0.0 Hz) due to the very different π electron densities. In the experiment, the researchers used many compounds, for example, 1,2-Difluoro-3-iodobenzene (cas: 64248-57-3Recommanded Product: 64248-57-3).

1,2-Difluoro-3-iodobenzene (cas: 64248-57-3) belongs to iodide derivatives. Organic iodides can be alkyl, alkenyl, or alkynyl, and all of them are very reactive toward with many kinds of nucleophiles. The C–I bond is the weakest of the carbon–halogen bonds. These bond strengths correlate with the electronegativity of the halogen, decreasing in the order F > Cl > Br > I. This periodic order also follows the atomic radius of halogens and the length of the carbon-halogen bond.Recommanded Product: 64248-57-3

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Zhang, Ying-Qi et al. published their research in Green Chemistry in 2019 | CAS: 877264-43-2

(5-Fluoro-2-iodophenyl)methanol (cas: 877264-43-2) belongs to iodide derivatives. Organoiodine compounds occur widely in organic chemistry, but are relatively rare in nature. The C–I bond is the weakest of the carbon–halogen bonds. These bond strengths correlate with the electronegativity of the halogen, decreasing in the order F > Cl > Br > I. This periodic order also follows the atomic radius of halogens and the length of the carbon-halogen bond.Product Details of 877264-43-2

Synthesis of functionalized 3-isochromanones via metal-free intramolecular alkoxylation-initiated cascade cyclization was written by Zhang, Ying-Qi;Zhu, Xin-Qi;Xu, Yin;Bu, Hao-Zhen;Wang, Jia-Le;Zhai, Tong-Yi;Zhou, Jin-Mei;Ye, Long-Wu. And the article was included in Green Chemistry in 2019.Product Details of 877264-43-2 This article mentions the following:

A metal-free intramol. alkoxylation-initiated cascade cyclization of allyl ether-tethered ynamides was developed. Various highly functionalized 3-isochromanones were obtained in generally good to excellent yields under mild reaction conditions. Moreover, this asym. cyclization was also realized via a stereocontrolled [3,3] rearrangement by employing a traceless chiral directing group. In addition, an unexpected [1,3] O-to-C rearrangement was observed in the case of the ynamide substrate bearing a phenyl-substituted alkene, which was distinctively different from the related gold catalysis. In the experiment, the researchers used many compounds, for example, (5-Fluoro-2-iodophenyl)methanol (cas: 877264-43-2Product Details of 877264-43-2).

(5-Fluoro-2-iodophenyl)methanol (cas: 877264-43-2) belongs to iodide derivatives. Organoiodine compounds occur widely in organic chemistry, but are relatively rare in nature. The C–I bond is the weakest of the carbon–halogen bonds. These bond strengths correlate with the electronegativity of the halogen, decreasing in the order F > Cl > Br > I. This periodic order also follows the atomic radius of halogens and the length of the carbon-halogen bond.Product Details of 877264-43-2

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Chen, Li-Ping et al. published their research in Organic Chemistry Frontiers in 2022 | CAS: 5460-32-2

4-Iodo-1,2-dimethoxybenzene (cas: 5460-32-2) belongs to iodide derivatives. Generally organic iodides can be divided into two classes of alkyl iodides and aryl iodides. Typical reactions of alkyl iodides include nucleophilic substitution, elimination, reduction, and the formation of organometallics. A typical method for synthesis of aromatic iodides is diazotization of primary aromatic amines followed by treatment of potassium iodide. Aliphatic alcohols are converted to alkyl iodides by treating with hydrogen iodide.Application of 5460-32-2

Palladium-catalyzed triple coupling of 2-iodoanisoles with aryl iodides to access 6H-dibenzopyrans was written by Chen, Li-Ping;Cheng, Shu-Lin;Fan, Xin-Yue;Zhu, Ji-Fa;Wang, Bi-Qin;Feng, Chun;Xiang, Shi-Kai. And the article was included in Organic Chemistry Frontiers in 2022.Application of 5460-32-2 This article mentions the following:

A palladium-catalyzed triple coupling of 2-iodoanisoles with aryl iodides was developed. 3-Methyl-2-pyridone was used as a ligand to accelerate the cross-coupling and suppress the homo-coupling of 2-iodoanisoles. A variety of 6H-dibenzopyran derivatives such as I [R = H, F, Cl, etc., R1 = 4-Me, 4-F, 4-MeO, etc.; R2 = 8-Me, 8-Cl, 8-Ph, etc.] was prepared by this method. In the experiment, the researchers used many compounds, for example, 4-Iodo-1,2-dimethoxybenzene (cas: 5460-32-2Application of 5460-32-2).

4-Iodo-1,2-dimethoxybenzene (cas: 5460-32-2) belongs to iodide derivatives. Generally organic iodides can be divided into two classes of alkyl iodides and aryl iodides. Typical reactions of alkyl iodides include nucleophilic substitution, elimination, reduction, and the formation of organometallics. A typical method for synthesis of aromatic iodides is diazotization of primary aromatic amines followed by treatment of potassium iodide. Aliphatic alcohols are converted to alkyl iodides by treating with hydrogen iodide.Application of 5460-32-2

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Ge, Yu et al. published their research in CrystEngComm in 2014 | CAS: 3268-21-1

1,4-Diiodo-2,3,5,6-tetramethylbenzene (cas: 3268-21-1) belongs to iodide derivatives. Organic iodides are widely used in organic synthesis. Halogenation of aromatic hydrocarbons is a very important reaction via an electrophilic aromatic substitution. Alkyl iodides react at a faster rate than alkyl fluorides due to the weak C-I bond.Safety of 1,4-Diiodo-2,3,5,6-tetramethylbenzene

Assembly of a series of zinc coordination polymers based on 1,4-bis[2-(4-pyridyl)ethenyl]-2,3,5,6-tetramethylbenzene and 1,3-benzenedicarboxylate derivatives was written by Ge, Yu;Li, Ni-Ya;Ji, Xue-Ying;Wang, Jun-Feng;Liu, Dong;Tang, Xiao-Yan. And the article was included in CrystEngComm in 2014.Safety of 1,4-Diiodo-2,3,5,6-tetramethylbenzene This article mentions the following:

Five new coordination polymers, namely, [Zn(1,3-BDC)(1,4-bpetmb)]n (1), {[Zn2(5-Cl-1,3-BDC)2(1,4-bpetmb)2]·MeCN}n (2), [Zn(5-NO2-1,3-BDC)(1,4-bpetmb)0.5]n (3), {[Zn(5-NH2-1,3-BDC)(1,4-bpetmb)0.5]·2H2O}n (4) and [Zn2(μ-OH)(1,3,5-BTC)(1,4-bpetmb)]n (5) have been synthesized under solvothermal conditions, based on the bis-pyridyl linker 1,4-bis[2-(4-pyridyl)ethenyl]-2,3,5,6-tetramethylbenzene (1,4-bpetmb) along with 1,3-benzenedicarboxylate (1,3-BDC) or its derivatives such as 5-chloro-1,3-benzenedicarboxylate (5-Cl-1,3-BDC), 5-nitro-1,3-benzenedicarboxylate (5-NO2-1,3-BDC), 5-amino-1,3-benzenedicarboxylate (5-NH2-1,3-BDC) and 1,3,5-benzenetricarboxylate (1,3,5-BTC). Compounds 1–5 have been characterized by elemental anal., IR spectroscopy, powder x-ray diffraction (PXRD) and unambiguously by single crystal X-ray diffraction anal. 1 And 2 feature the 2D (4,4) net. 3 Comprises an interlocked 3D framework, and the 3D framework is derived from the inclined interpenetration of the 2D (4,4) net. 4 Exhibits a thick 2D (3,4)-connected network with a Schlafli symbol of (63)(65·8). 5 Displays a 3D two-fold interpenetrating (3,5)-connected framework with the Schlafli symbol of (63)(67·83). Thermal stability and solid-state photoluminescence properties of 1–5 were also investigated. In the experiment, the researchers used many compounds, for example, 1,4-Diiodo-2,3,5,6-tetramethylbenzene (cas: 3268-21-1Safety of 1,4-Diiodo-2,3,5,6-tetramethylbenzene).

1,4-Diiodo-2,3,5,6-tetramethylbenzene (cas: 3268-21-1) belongs to iodide derivatives. Organic iodides are widely used in organic synthesis. Halogenation of aromatic hydrocarbons is a very important reaction via an electrophilic aromatic substitution. Alkyl iodides react at a faster rate than alkyl fluorides due to the weak C-I bond.Safety of 1,4-Diiodo-2,3,5,6-tetramethylbenzene

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Lovely, Carl J. et al. published their research in Heterocycles in 2003 | CAS: 15813-09-9

4,5-Diiodo-1H-imidazole (cas: 15813-09-9) belongs to iodide derivatives. Organic iodides can be alkyl, alkenyl, or alkynyl, and all of them are very reactive toward with many kinds of nucleophiles. Organoiodine lubricants can be used with titanium, stainless steels, and other metals which tend to seize up with conventional lubricants: organoiodine lubricants can be used in turbines and spacecraft, and as a cutting oil in machining.Safety of 4,5-Diiodo-1H-imidazole

Regioselective synthesis of 1-benzyl- and 1-methyl-4-vinylimidazole and their reactions with N-phenylmaleimide was written by Lovely, Carl J.;Du, Hongwang;Dias, H. V. Rasika. And the article was included in Heterocycles in 2003.Safety of 4,5-Diiodo-1H-imidazole This article mentions the following:

The regioselective synthesis of 1-benzyl- and 1-methyl-4-vinylimidazole from 4,5-diiodoimidazole is described. Their Diels-Alder reactions with N-phenylmaleimide provide a variety of adducts, including the anticipated enamine and the corresponding aromatized isomer. However, addnl. products including ene adducts, a bis Diels-Alder adduct and oxidation products were isolated. In the experiment, the researchers used many compounds, for example, 4,5-Diiodo-1H-imidazole (cas: 15813-09-9Safety of 4,5-Diiodo-1H-imidazole).

4,5-Diiodo-1H-imidazole (cas: 15813-09-9) belongs to iodide derivatives. Organic iodides can be alkyl, alkenyl, or alkynyl, and all of them are very reactive toward with many kinds of nucleophiles. Organoiodine lubricants can be used with titanium, stainless steels, and other metals which tend to seize up with conventional lubricants: organoiodine lubricants can be used in turbines and spacecraft, and as a cutting oil in machining.Safety of 4,5-Diiodo-1H-imidazole

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Rebstock, Anne-Sophie et al. published their research in Tetrahedron in 2004 | CAS: 22918-03-2

4-Chloro-2-iodopyridine (cas: 22918-03-2) belongs to iodide derivatives. Organic iodides are widely used in organic synthesis. Halogenation of aromatic hydrocarbons is a very important reaction via an electrophilic aromatic substitution. Polyiodoorganic compounds are sometimes employed as X-ray contrast agents, in fluoroscopy, a type of medical imaging. This application exploits the X-ray absorbing ability of the heavy iodine nucleus.Name: 4-Chloro-2-iodopyridine

Regioselectivities in deprotonation of 2-(4-chloro-2-pyridyl)benzoic acid and corresponding ester and amide was written by Rebstock, Anne-Sophie;Mongin, Florence;Trecourt, Francois;Queguiner, Guy. And the article was included in Tetrahedron in 2004.Name: 4-Chloro-2-iodopyridine This article mentions the following:

Upon treatment of Et 2-(4-chloro-2-pyridyl)benzoic acid, 2-(4-chloro-2-pyridyl)benzoate, and N,N-diisopropyl-2-(4-chloro-2-pyridyl)benzamide with LTMP at -75 °C in THF, the lithio derivatives at C5′ are generated regiospecifically, as demonstrated by subsequent quenching with electrophiles. The lithio derivative at C3′ is only evidenced from the benzamide at higher temperature (-50 °C), when treated with LTMP in THF; it instantly cyclizes to 1-chloro-4-azafluorenone. The latter is converted to onychine, an alkaloid endowed with anticandidal activity. In the experiment, the researchers used many compounds, for example, 4-Chloro-2-iodopyridine (cas: 22918-03-2Name: 4-Chloro-2-iodopyridine).

4-Chloro-2-iodopyridine (cas: 22918-03-2) belongs to iodide derivatives. Organic iodides are widely used in organic synthesis. Halogenation of aromatic hydrocarbons is a very important reaction via an electrophilic aromatic substitution. Polyiodoorganic compounds are sometimes employed as X-ray contrast agents, in fluoroscopy, a type of medical imaging. This application exploits the X-ray absorbing ability of the heavy iodine nucleus.Name: 4-Chloro-2-iodopyridine

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Amino, Yusuke’s team published research in Bioscience, Biotechnology, and Biochemistry in 81 | CAS: 161370-66-7

Bioscience, Biotechnology, and Biochemistry published new progress about 161370-66-7. 161370-66-7 belongs to iodides-buliding-blocks, auxiliary class Chiral,Iodide,Amine,Aliphatic hydrocarbon chain,Ester,Amide, name is (S)-tert-Butyl 2-((tert-butoxycarbonyl)amino)-4-iodobutanoate, and the molecular formula is C13H24INO4, Safety of (S)-tert-Butyl 2-((tert-butoxycarbonyl)amino)-4-iodobutanoate.

Amino, Yusuke published the artcileSynthesis and evaluation of L-cystathionine as a standard for amino acid analysis, Safety of (S)-tert-Butyl 2-((tert-butoxycarbonyl)amino)-4-iodobutanoate, the publication is Bioscience, Biotechnology, and Biochemistry (2017), 81(1), 95-101, database is CAplus and MEDLINE.

L-Cystathionine is a key nonprotein amino acid related to metabolic conditions. The quant. determination of L-cystathionine in physiol. fluids by amino acid anal. is important for clin. diagnosis; however, certified reference material for L-cystathionine with satisfactory purity, content, and quantity has been unavailable until recently. Consequently, a practical and simple method for the preparation of L-cystathionine was examined, which involves thioalkylation of N-tert-butoxycarbonyl-L-cysteine tert-Bu ester, derived from L-cystine, with (2S)-2-(tert-butoxycarbonyl)amino-4-iodobutanoic acid tert-Bu ester, derived from L-aspartic acid, to obtain L-cystathionine with protecting groups, followed by single-step deprotection under mild conditions. This method produces L-cystathionine in high purity (99.4%) and having sufficient percentage content according to amino acid anal., which could be used as a standard for the amino acid anal. of physiol. fluids.

Bioscience, Biotechnology, and Biochemistry published new progress about 161370-66-7. 161370-66-7 belongs to iodides-buliding-blocks, auxiliary class Chiral,Iodide,Amine,Aliphatic hydrocarbon chain,Ester,Amide, name is (S)-tert-Butyl 2-((tert-butoxycarbonyl)amino)-4-iodobutanoate, and the molecular formula is C13H24INO4, Safety of (S)-tert-Butyl 2-((tert-butoxycarbonyl)amino)-4-iodobutanoate.

Referemce:
https://en.wikipedia.org/wiki/Iodide,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Watanabe, Daisuke’s team published research in Tetrahedron Letters in 58 | CAS: 161370-66-7

Tetrahedron Letters published new progress about 161370-66-7. 161370-66-7 belongs to iodides-buliding-blocks, auxiliary class Chiral,Iodide,Amine,Aliphatic hydrocarbon chain,Ester,Amide, name is (S)-tert-Butyl 2-((tert-butoxycarbonyl)amino)-4-iodobutanoate, and the molecular formula is C12H15BF2O2, Computed Properties of 161370-66-7.

Watanabe, Daisuke published the artcileSynthesis of desmosine-d4: Improvement of isotopic purity by D-H exchange of amino groups, Computed Properties of 161370-66-7, the publication is Tetrahedron Letters (2017), 58(12), 1194-1197, database is CAplus.

Desmosine is a crosslinking pyridinium amino acid of elastin, which is a useful biomarker for the diagnosis of chronic obstructive pulmonary disease (COPD) by LC-MS/MS anal. We previously reported a synthesis of desmosine-d4, which is useful as an internal standard for quant. LC-MS/MS anal. of desmosines, by deuterogenation of an alkyne group; however, the isotopic purity of the desmosine-d4 was only ca. 50%. The present report describes a new synthesis of desmosine-d4 that improves the isotopic purity to ca. 90% by exchanging the protons of the amino groups to deuterium using deuterogenation.

Tetrahedron Letters published new progress about 161370-66-7. 161370-66-7 belongs to iodides-buliding-blocks, auxiliary class Chiral,Iodide,Amine,Aliphatic hydrocarbon chain,Ester,Amide, name is (S)-tert-Butyl 2-((tert-butoxycarbonyl)amino)-4-iodobutanoate, and the molecular formula is C12H15BF2O2, Computed Properties of 161370-66-7.

Referemce:
https://en.wikipedia.org/wiki/Iodide,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Schaefer, Bernhard’s team published research in European Journal of Organic Chemistry in 2021 | CAS: 638-45-9

European Journal of Organic Chemistry published new progress about 638-45-9. 638-45-9 belongs to iodides-buliding-blocks, auxiliary class Iodide,Aliphatic hydrocarbon chain, name is 1-Iodohexane, and the molecular formula is C6H13I, Formula: C6H13I.

Schaefer, Bernhard published the artcileDitopic Hexadentate Ligands with a Central Dihydrobenzo-diimidazole Unit Forming a [2×2] Zn4 Grid Complex, Formula: C6H13I, the publication is European Journal of Organic Chemistry (2021), 2021(16), 2301-2310, database is CAplus.

A family of ditopic hexadentate ligands based on the parent compound 2,6-bis(6-(pyrazol-1-yl)pyridin-2-yl)-1,5-dihydrobenzo[1,2-d:4,5-d’]diimidazole (L) was developed and synthesized by using a straightforward condensation reaction, which forms the interlinking central benzo[1,2-d:4,5-d’]diimidazole bridge in the ligand backbone. The two secondary amine groups of the benzodiimidazole unit tautomerize and allow the formation of two tauto-conformers, which upon treatment with metal salts forms different isomeric coordination complexes. Here authors report six new derivatives (1–6) that can tautomerize (varying the pyrazolylpyridine part) and 14 derivatives (7–13) with different alkyl and benzyl substitution on secondary amino groups (of L) that prevent the tautomerization. This way, it is possible to study the properties of isomeric coordination complexes and their intrinsic cooperativity by the example of [2×2] grid complexes in the future. A [2×2] Zn4 complex of the ligand L was synthesized and structurally characterized.

European Journal of Organic Chemistry published new progress about 638-45-9. 638-45-9 belongs to iodides-buliding-blocks, auxiliary class Iodide,Aliphatic hydrocarbon chain, name is 1-Iodohexane, and the molecular formula is C6H13I, Formula: C6H13I.

Referemce:
https://en.wikipedia.org/wiki/Iodide,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com