Tag: 200-300

Application In Synthesis of Trimethylsulfoxonium iodideIn 2021 ,《Synthesis of 2-aminothiazoles via rhodium-catalyzed carbenoid insertion/annulation of sulfoxonium ylides with thioureas》 was published in Chinese Chemical Letters. The article was written by Chen, Yuncan; Lv, Shan; Lai, Ruizhi; Xu, Yingying; Huang, Xin; Li, Jianglian; Lv, Guanghui; Wu, Yong. The article contains the following contents:

Sulfoxonium ylides as carbene precursors couple smoothly with thioureas in the presence of 5 mol% of rhodium(II) acetate dimmer via carbenoid insertion to afford the corresponding 2-aminothiazoles with high chemoselectivity, provided a facile and efficient approach to access a variety of 2-aminothiazole derivatives with good functional groups tolerance. In addition to this study using Trimethylsulfoxonium iodide, there are many other studies that have used Trimethylsulfoxonium iodide(cas: 1774-47-6Application In Synthesis of Trimethylsulfoxonium iodide) was used in this study.

Trimethylsulfoxonium iodide(cas: 1774-47-6) is a sulfoxonium salt. It is used to generate dimethyloxosulfonium methylide by reaction with sodium hydride. The latter compound is used as a methylene-transfer reagent, and is used to prepare epoxides.Application In Synthesis of Trimethylsulfoxonium iodide

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

HPLC of Formula: 516-12-1In 2020 ,《A generalized one-step in situ formation of metal sulfide/reduced graphene oxide nanosheets toward high-performance supercapacitors》 appeared in Science China Materials. The author of the article were Zhang, Kaiyang; Wei, Yuanhao; Huang, Jun; Xiao, Yingbo; Yang, Weizu; Hu, Ting; Yuan, Kai; Chen, Yiwang. The article conveys some information:

Metal sulfides are promising candidates for supercapacitors, but their slow reaction kinetics hinders their electrochem. performance. Large electrochem. surface area and combination with conductive carbon are potential methods to improve their capacitive performance. However, seeking for a generalized and simple approach to prepare two-dimensional composites of metal sulfide and conductive carbon for supercapacitors is challengeable. Herein, a generalized and facile one-step pyrolysis method was designed for in situ growth of cobalt nickel sulfides (CoNi2S4) on reduced graphene oxide (rGO) nanosheets (CoNi2S4/rGO) under mild conditions. The as-prepared CoNi2S4/rGO materials possess the nanoparticles-on-nanosheets structure, which is effective to provide a myriad of active sites and optimized electron/ion diffusion pathway. Benefiting from those advantages, the resultant CoNi2S4/rGO electrodes exhibit impressed specific capacitances of 1526 and 988 F g-1 at 2 and 20 A g-1, resp. The supercapacitors based on CoNi2S4/rGO showcase an operation potential window of 1.6 V, and energy d. of 54.8 W h kg-1 at the power d. of 798 W kg-1. The capacitance retention of the supercapacitor is about 93.7% after 8000 cycles at 3 A g-1. In addition to this study using 1-Iodopyrrolidine-2,5-dione, there are many other studies that have used 1-Iodopyrrolidine-2,5-dione(cas: 516-12-1HPLC of Formula: 516-12-1) was used in this study.

1-Iodopyrrolidine-2,5-dione(cas: 516-12-1) is used in the preparation of vinyl sulfones from olefins and benzenesulfinic acid. It acts as a source for I+ and involved in Hunsdiecker reactions for the conversion of cinnamic acids, and propiolic acids to the corresponding alfa-halostyrenes and 1-halo-1-alkynes respectively. HPLC of Formula: 516-12-1

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

In 2022,Suri Babu, Undamatla; Singam, Maneesh Kumar Reddy; Kumar, Muniganti Naveen; Nanubolu, Jagadeesh Babu; Sridhar Reddy, Maddi published an article in Organic Letters. The title of the article was 《Palladium-Catalyzed Carbo-Aminative Cyclization of 1,6-Enynes: Access to Naphthyridinone Derivatives》.Safety of 4-Chloro-2-iodoaniline The author mentioned the following in the article:

A general approach to naphthyridinones I [R = H, 8-Me, 7-F, etc.; Ar = Ph, 4-MeC6H4, Bn, etc.; Ar1 = Ph, 4-MeC6H4, 2-thienyl, etc.] was described via Pd-catalyzed annulation of 1,6-enynes with 2-iodoanilines. This protocol represents a rare carbo-aminative annulative cyclization via 6-endo-trig mode, subduing the well documented exo-trig/dig cyclizations. Regioselective aryl palladation of alkyne followed by Heck type intramol. coupling before isomerization were key in realizing this cascade. In addition to this study using 4-Chloro-2-iodoaniline, there are many other studies that have used 4-Chloro-2-iodoaniline(cas: 63069-48-7Safety of 4-Chloro-2-iodoaniline) was used in this study.

4-Chloro-2-iodoaniline(cas: 63069-48-7) belongs to anime. Reaction with nitrous acid (HNO2), which functions as an acylating agent that is a source of the nitrosyl group (―NO), converts aliphatic primary amines to nitrogen and mixtures of alkenes and alcohols corresponding to the alkyl group in a complex process. This reaction has been used for analytical determination of primary amino groups in a procedure known as the Van Slyke method.Safety of 4-Chloro-2-iodoaniline

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

In 2022,Leushukou, Andrei A.; Krech, Anastasiya V.; Hurski, Alaksiej L. published an article in Organic Letters. The title of the article was 《Visible-Light-Promoted Nickel-Catalyzed Cross-Coupling of Alkyltitanium Alkoxides with Aryl and Alkenyl Halides》.SDS of cas: 15854-87-2 The author mentioned the following in the article:

The reported alkyltitanium alkoxides generated in situ from Grignard reagents and Ti(OiPr)4 undergone a photocatalyst-free nickel-catalyzed cross-coupling with organic halides upon irradation with blue light. Mechanistic studies suggested that the reaction proceeds through radical intermediates formed by photochem. decomposition of the alkyltitanium reagents. Various aryl, heteroaryl, and vinyl halides was efficiently alkylated under the reported conditions, including those containing ester and amide groups. The experimental process involved the reaction of 4-Iodopyridine(cas: 15854-87-2SDS of cas: 15854-87-2)

4-Iodopyridine(cas: 15854-87-2) is used as a reagent in the synthesis of indazolylamides as glucocorticoid receptor agonists. 4-Iodopyridine is a halogenated heterocycle that is a building block for proteomics research.SDS of cas: 15854-87-2

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

In 2022,Dong, Cong; Mai, Shaoyu; Wang, Shuai; Li, Xin; Song, Qiuling published an article in Organic Chemistry Frontiers. The title of the article was 《Base-promoted anaerobic intramolecular cyclization synthesis of 4,5-disubstituted-1,2,3-thiadiazoles》.Product Details of 591-18-4 The author mentioned the following in the article:

An alkali-promoted, transition-metal-free and oxidant-free method to construct 4,5-disubstituted-1,2,3-thiadiazoles I [R = 2-NO2, 3-NO2; R1 = H, 2-MeO, 4-F, etc.] from N-tosylhydrazone-bearing thiocarbamates by employing a sustainable intramol. reaction strategy had been developed. This reaction featured high efficiency and good functional group compatibility, readily available starting materials and valuable products. Furthermore, this method had great potential in the synthesis of natural products, pharmaceuticals and materials. In the part of experimental materials, we found many familiar compounds, such as 1-Bromo-3-iodobenzene(cas: 591-18-4Product Details of 591-18-4)

1-Bromo-3-iodobenzene(cas: 591-18-4) has been used in the preparation of 1-(3′-bromophenyl)-3,3,4,4,5,5,6,6,7,7,8,8,9,9,10,10,10-heptadecafluorodec-1-ene and 1-(3′-bromophenyl)-3,3,4,4,5,5,6,6,7,7,8,8,8-tridecafluorooct-1-ene.Product Details of 591-18-4

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Mertens, R. Tyler; Greif, Charles E.; Coogle, James T.; Berger, Gilles; Parkin, Sean; Watson, Mark D.; Awuah, Samuel G. published an article in 2022. The article was titled 《Stable Au(I) catalysts for oxidant-free C-H functionalization with iodoarenes》, and you may find the article in Journal of Catalysis.Electric Literature of C6H5IO The information in the text is summarized as follows:

Herein, the development of novel tricoordinate Au(I) catalysts supported by N,N-bidentate ligands and ligated by phosphine or arsine ligands for C-H functionalization without external oxidants to form biaryls with no homocoupling was reported. The unsym. character of the Au(I) catalyst was critical to facilitating this necessary orthogonal transformation. This study unveils yet another potential of Au(I) catalysis in biaryl synthesis. The experimental process involved the reaction of 3-Iodophenol(cas: 626-02-8Electric Literature of C6H5IO)

3-Iodophenol(cas: 626-02-8) belongs to organic iodides. The carbon-iodine bond is weaker than other carbon-halogen bonds due to the poor electronegative nature of the iodine atom. Electric Literature of C6H5IO Organic iodides can be alkyl, alkenyl, or alkynyl, and all of them are very reactive toward with many kinds of nucleophiles.

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Samadi, Saadi; Ashouri, Akram; Rashid, Hersh I.; Majidian, Shiva; Mahramasrar, Mahsa published their research in New Journal of Chemistry in 2021. The article was titled 《Immobilization of (L)-valine and (L)-valinol on SBA-15 nanoporous silica and their application as chiral heterogeneous ligands in the Cu-catalyzed asymmetric allylic oxidation of alkenes》.Application of 619-58-9 The article contains the following contents:

SBA-15 nanoporous silica was synthesized by hydrothermal method using P123 surfactant and tetraethoxyortosilicate in acidic condition and then functionalized by 3-chloropropyltrimethoxysilane. Next, by immobilization of chiral amino acid (S)-2-amino-3-Me butanoic acid (L-valine) and chiral amino alc. (S)-2-amino-3-methylbutane-1-ol (L-valinol), prepared via the reduction of L-valine by NaBH4/I2 in THF, on functionalized-SBA-15, chiral heterogeneous ligands AL*-i-Pr-SBA-15 and AA*-i-Pr-SBA-15 were prepared and characterized by FT-IR, XRD, TGA, EDX, SEM, BET-BJH techniques. The asym. allylic oxidation of alkenes was done using copper-complexes of these ligands and the as-synthesized peresters. The reactions were optimized by varying various parameters such as temperature, solvent, amount of chiral heterogeneous ligand, as well as the type and amount of copper salt. Under optimized conditions, 6 mg of AL*-i-Pr-SBA-15 and 3.2 mol% of Cu(CH3CN)4PF6 in acetonitrile at 50°C, the chiral allylic ester was obtained with 80% yield and 39% enantiomeric excess in 24 h. The recyclability of the chiral heterogeneous catalysts was also evaluated without significant reduction in the reaction results up to three runs.4-Iodobenzoic acid(cas: 619-58-9Application of 619-58-9) was used in this study.

4-Iodobenzoic acid(cas: 619-58-9) belongs to organic iodides. Organic iodides are used in veterinary products (Organic Iodide Powder) as a nutritional source of iodine.Application of 619-58-9 In the chemical industry, alkyl iodides serve as excellent alkylating agents and, specifically, methyl iodide is used as a methylating agent in the synthesis of various pharmaceutical drugs.

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Sun, Xu; Guo, Xiao-Qiang; Chen, Lian-Mei; Kang, Tai-Ran published their research in Chemistry – A European Journal in 2021. The article was titled 《Synthesis, Characterization of Spirocyclic λ3-Iodanes and Their Application to Prepare 4,1-Benzoxazepine-2,5-diones and 1,3-Diynes》.Related Products of 625-99-0 The article contains the following contents:

Herein, a [3+2] cycloaddition of aza-oxyallylic cations I [R = H, 6-Cl, 5-NO2, 5-F; R1 = 2-bromophenyl, 4-(ethoxycarbonyl)benzen-1-yl, tris(propan-2-yl)silyl, etc.] with ethynylbenziodoxolones R2ONHC(O)C(CH3)2Br [R2 = allyl, i-Pr, Bn, (2,4-dichlorophenyl)methyl, etc.] for synthesis of new λ3-iodanes containing spirocyclic 4-oxazolidinone II is described. This cyclic λ3-iodanes II display stability in air and excellent solubility in organic solvent. Using the above compounds as substrate II, both the 4,1-benzoxazepine-2,5-diones III [R3 = Me, allyl, (2,4-dichlorophenyl)methyl, etc.; R4 = H, 7-Me, 8-Cl, 7-CF3] and sym. 1,3-diynes derivatives R5CCCCR5 [R5 = Ph, 2-bromophenyl, 1-naphthyl, etc.] were afforded in high yield under copper(I)-catalyzed conditions. After reading the article, we found that the author used 1-Chloro-3-iodobenzene(cas: 625-99-0Related Products of 625-99-0)

1-Chloro-3-iodobenzene(cas: 625-99-0) belongs to organic iodides. The carbon-iodine bond is weaker than other carbon-halogen bonds due to the poor electronegative nature of the iodine atom. In general, organic iodides are light-sensitive and turn yellow during storage, owing to the formation of iodine.Related Products of 625-99-0

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

《Carboxylic Acid Deoxyfluorination and One-Pot Amide Bond Formation Using Pentafluoropyridine (PFP)》 was written by Brittain, William D. G.; Cobb, Steven L.. SDS of cas: 88-67-5 And the article was included in Organic Letters in 2021. The article conveys some information:

The present work describes the application of pentafluoropyridine (PFP), a cheap com. available reagent, in the deoxyfluorination of carboxylic acids RC(O)OH (R = Et, adamantan-1-yl, Ph, 2-iodophenyl, etc.) to acyl fluorides RC(O)F. The acyl fluorides can be formed from a range of acids under mild conditions. The PFP that can be utilized in a one-pot amide bond formation via in situ generation of acyl fluorides was also demonstrated. This one-pot deoxyfluorination amide bond-forming reaction gives ready access to amides RC(O)N(R1)R2 (R1 = H, Me, Et; R2 = Et, Ph, 3-nitrophenyl, etc.) in yields of ≤94%. In the experiment, the researchers used 2-Iodobenzoic acid(cas: 88-67-5SDS of cas: 88-67-5)

2-Iodobenzoic acid(cas: 88-67-5) belongs to organic iodides. Alkyl iodides react at a faster rate than alkyl fluorides due to the weak C-I bond.SDS of cas: 88-67-5Iodo alkanes participate in a variety of organic synthesis reactions, which include the Simmons–Smith reaction (cyclopropanation using iodomethane), Williamson ether synthesis, Wittig reaction, Grignard reaction, alkyl coupling reactions, and Wurtz reaction.

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

《Copper-Catalyzed Modular Assembly of Polyheterocycles》 was written by Wang, Qian; Tuinhof, Jesse; Mgimpatsang, Kumchok C.; Kurpiewska, Katarzyna; Kalinowska-Tluscik, Justyna; Doemling, Alexander. Related Products of 88-67-5 And the article was included in Journal of Organic Chemistry in 2020. The article conveys some information:

Easy operation, readily accessible starting materials, and short synthesis of the privileged scaffold indeno[1,2-c]isoquinolinones I (R1 = H, 3-MeO, 2-Me, 2-NO2, etc.; R2 = H, Me, cyclopentyl, 4-chlorophenyl, etc.; R3 = tert-Bu, benzyl, 2-methoxy-2-oxoethyl, 2-ethylphenyl, etc.; R4 = H, 8,9-dimethoxy) were achieved by an multicomponent reaction (MCR)-based protocol via an ammonia-Ugi-four component reaction (4CR)/copper-catalyzed annulation sequence. The optimization and scope and limitations of this short and general sequence are described. The methodol. allows an efficient construction of a wide variety of indenoisoquinolinones I in just two steps. The experimental process involved the reaction of 2-Iodobenzoic acid(cas: 88-67-5Related Products of 88-67-5)

2-Iodobenzoic acid(cas: 88-67-5) belongs to organic iodides. The carbon-iodine bond is weaker than other carbon-halogen bonds due to the poor electronegative nature of the iodine atom. Alkyl iodides react at a faster rate than alkyl fluorides due to the weak C-I bond.Related Products of 88-67-5

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com