Tag: 200-300

In 2019,Synlett included an article by Wu, Xiang-mei; Yan, Guo-bing. Related Products of 591-18-4. The article was titled 《Copper-Catalyzed Synthesis of S-Aryl Dithiocarbamates from Tetraalkylthiuram Disulfides and Aryl Iodides in Water》. The information in the text is summarized as follows:

An efficient approach for the copper-catalyzed synthesis of aryl dithiocarbamates R1SC(S)N(R2)2 (R1 = 2-BrC6H4, 1,3,5-(Me)3C6H2, thiophen-2-yl, etc.; R2 = Me, Et) from aryl iodides R1I and tetraalkylthiuram disulfides N((R2)2)C(S)SSC(S)N((R2)2) in water is described. Without addnl. ligand and organic solvent, the coupling reaction could provide a series of S-aryl dithiocarbamates in moderate to good yields. In the experimental materials used by the author, we found 1-Bromo-3-iodobenzene(cas: 591-18-4Related Products of 591-18-4)

1-Bromo-3-iodobenzene(cas: 591-18-4) has been used in the preparation of 1-(3′-bromophenyl)-3,3,4,4,5,5,6,6,7,7,8,8,9,9,10,10,10-heptadecafluorodec-1-ene and 1-(3′-bromophenyl)-3,3,4,4,5,5,6,6,7,7,8,8,8-tridecafluorooct-1-ene.Related Products of 591-18-4 Further, it is involved in the preparation of oxygen-tethered 1,6-enynes.

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

《Dibenzofuran Derivatives Inspired from Cercosporamide as Dual Inhibitors of Pim and CLK1 Kinases》 was written by Dao, Viet Hung; Ourliac-Garnier, Isabelle; Loge, Cedric; McCarthy, Florence O.; Bach, Stephane; da Silva, Teresinha Goncalves; Denevault-Sabourin, Caroline; Thiefaine, Jerome; Baratte, Blandine; Robert, Thomas; Gouilleux, Fabrice; Brachet-Botineau, Marie; Bazin, Marc-Antoine; Marchand, Pascal. HPLC of Formula: 626-02-8 And the article was included in Molecules in 2021. The article conveys some information:

Pim kinases (proviral integration site for Moloney murine leukemia virus kinases) are overexpressed in various types of hematol. malignancies and solid carcinomas, and promote cell proliferation and survival. Thus, Pim kinases are validated as targets for antitumor therapy. In this context, our combined efforts in natural product-inspired library generation and screening furnished very promising dibenzo[b,d]furan derivatives derived from cercosporamide. Among them, lead compound 44 was highlighted as a potent Pim-1/2 kinases inhibitor with an addnl. nanomolar IC50 value against CLK1 (cdc2-like kinases 1) and displayed a low micromolar anticancer potency towards the MV4-11 (AML) cell line, expressing high endogenous levels of Pim-1/2 kinases. The design, synthesis, structure-activity relationship, and docking studies are reported herein and supported by enzyme, cellular assays, and Galleria mellonella larvae testing for acute toxicity. After reading the article, we found that the author used 3-Iodophenol(cas: 626-02-8HPLC of Formula: 626-02-8)

3-Iodophenol(cas: 626-02-8) belongs to organic iodides. The carbon-iodine bond is weaker than other carbon-halogen bonds due to the poor electronegative nature of the iodine atom. In general, organic iodides are light-sensitive and turn yellow during storage, owing to the formation of iodine.HPLC of Formula: 626-02-8

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

《Photocatalytic CO2 reduction of C/ZnO nanofibers enhanced by an Ni-NiS cocatalyst》 was published in Nanoscale in 2020. These research results belong to Deng, Hongzhao; Xu, Feiyan; Cheng, Bei; Yu, Jiaguo; Ho, Wingkei. Safety of 1-Iodopyrrolidine-2,5-dione The article mentions the following:

The photocatalytic reduction of CO2 into valuable hydrocarbon fuels via solar energy is a promising strategy for carbon utilization. In the present paper, a hierarchical Ni-NiS/C/ZnO photocatalyst was prepared via the in situ photodeposition of compact Ni-NiS nanosheets onto C/ZnO electrospun nanofibers. The existence of metallic Ni and NiS was confirmed by XPS. Photoluminescence (PL) and time-resolved PL spectra revealed that the cocatalyst Ni-NiS enhanced the charge separation efficiency of the C/ZnO nanofibers. The as-prepared Ni-NiS/C/ZnO showed enhanced CO2 reduction activity, with CO and CH4 production rates 10 and 15 times greater than those of pristine C/ZnO under 350 W visible light illumination. The intermediates of CH3O-, HCHO, and HCOO- were detected by in situ Fourier transform IR spectroscopy, confirming that CO2 reduction is a complex reaction with multiple steps. The 13C isotopic tracer method proved that CH4 and CO were obtained from the reduction of CO2 rather than from other carbon species in the environment. The amorphous carbon in C/ZnO could promote optical absorption, improve conductivity and reduce the interfacial charge transport resistance. Ni-NiS improved the electron-hole-pair separation of the C/ZnO nanofibers. The observed enhancement in photocatalytic activity was largely attributed to higher light utilization and effective electron-hole separation This work proves that Ni-NiS is a promising cocatalyst to ZnO for photocatalytic CO2 reduction In the experiment, the researchers used many compounds, for example, 1-Iodopyrrolidine-2,5-dione(cas: 516-12-1Safety of 1-Iodopyrrolidine-2,5-dione)

1-Iodopyrrolidine-2,5-dione(cas: 516-12-1) is used in the preparation of vinyl sulfones from olefins and benzenesulfinic acid. It acts as a source for I+ and involved in Hunsdiecker reactions for the conversion of cinnamic acids, and propiolic acids to the corresponding alfa-halostyrenes and 1-halo-1-alkynes respectively. Safety of 1-Iodopyrrolidine-2,5-dione

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

The author of 《Immobilization of palladium nanoparticles on Metformin-functionalized graphene oxide as a heterogeneous and recyclable nanocatalyst for Suzuki coupling reactions and reduction of 4-nitrophenol》 were Hemmati, Saba; Mehrazin, Lida; Pirhayati, Mozhgan; Veisi, Hojat. And the article was published in Polyhedron in 2019. Reference of 1-Iodo-4-methylbenzene The author mentioned the following in the article:

In this study, Pd nanoparticles supported on Metformin modified graphene oxide (GO-Met-Pd) is proposed as a green heterogeneous catalyst. The structural properties of the as-synthesized nanocatalyst were determined by X-ray diffraction (XRD), Fourier transformed IR (FT-IR) spectroscopy, transmission electron microscopy (TEM), field emission SEM (FESEM), energy dispersive X-ray spectroscopy (EDS), wavelength-dispersive X-ray spectroscopy (WDX) and inductively coupled plasma (ICP). Activity of the catalyst was investigated by focusing on the Suzuki-Miyaura coupling reaction and room-temperature reduction of 4-nitrophenol (4-NP), as model reactions. The catalyzed reactions provided high yields of biphenyl compounds through the Suzuki-Miyaura reaction and outlined highly efficient conversion of 4-NP to its reduced form. Moreover, no significant Pd leaching was detected in the reaction solutions and the catalyst could be recovered, at least, 6 times without any considerable loss of its catalytic activity. The experimental part of the paper was very detailed, including the reaction process of 1-Iodo-4-methylbenzene(cas: 624-31-7Reference of 1-Iodo-4-methylbenzene)

1-Iodo-4-methylbenzene(cas: 624-31-7) is used in wide range of medicals industrial applications as well as in pharmaceutical intermediates, polarizing films for Liquid Crystal Display (LCD) chemicals.Reference of 1-Iodo-4-methylbenzene

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

The author of 《Straightforward sequential and one-pot synthesis of a pentasaccharide repeating unit corresponding to the cell wall O-antigen of Shigella boydii type 18》 were Shit, Pradip; Gucchait, Arin; Misra, Anup Kumar. And the article was published in Tetrahedron in 2019. Application of 516-12-1 The author mentioned the following in the article:

Synthesis of a pentasaccharide repeating unit corresponding to the cell of wall O-antigen Shigella boydii type 18 has been achieved by sequential as well as iterative glycosylation in one-pot. Use of p-methoxybenzyl group (PMB) as an in situ removable protecting group allowed obtaining the desired pentasaccharide derivative in a generalized glycosylation condition and in one-pot condition. Synthesis of a beta-L-rhamnosidic linkage present in the mol. has been successfully achieved using L-rhamnosyl thioglycoside donor having a picoloyl group at remote C-3 position influencing beta selectivity in the glycosylation. A combination of N-iodosuccinimide (NIS) and perchloric acid supported over silica (HClO4-SiO2) has been used as thiophilic glycosylation promoter in all glycosylation reactions. TEMPO mediated selective oxidation of the primary hydroxyl group has been carried out at the late stage of the synthetic strategy.1-Iodopyrrolidine-2,5-dione(cas: 516-12-1Application of 516-12-1) was used in this study.

1-Iodopyrrolidine-2,5-dione(cas: 516-12-1) is used in the preparation of vinyl sulfones from olefins and benzenesulfinic acid. It acts as a source for I+ and involved in Hunsdiecker reactions for the conversion of cinnamic acids, and propiolic acids to the corresponding alfa-halostyrenes and 1-halo-1-alkynes respectively. Application of 516-12-1

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

The author of 《Palladium-Catalyzed Domino Heck/C-H Activation/Decarboxylation: A Rapid Entry to Fused Isoquinolinediones and Isoquinolinones》 were Luo, Xiai; Zhou, Liwei; Lu, Haiyan; Deng, Guobo; Liang, Yun; Yang, Chunming; Yang, Yuan. And the article was published in Organic Letters in 2019. COA of Formula: C7H5IO2 The author mentioned the following in the article:

A new palladium-catalyzed tandem cyclization of various alkene-tethered aryl iodides has been presented. In this protocol, o-bromobenzoic acids are employed as coupling parters to achieve the insertion of aromatic rings by the cleavage of C(sp2)-Br and decarboxylation, thus assembling various dibenzoisoquinolinediones and dibenzoisoquinolinones. In addition, a seven-membered ring can be constructed by the use of 8-bromo-1-naphthoic acid. Notably, this approach enables regioselective product formation and features broad substrate scope.2-Iodobenzoic acid(cas: 88-67-5COA of Formula: C7H5IO2) was used in this study.

2-Iodobenzoic acid(cas: 88-67-5) belongs to organic iodides. Generally organic iodides can be divided into two classes of alkyl iodides and aryl iodides. Typical reactions of alkyl iodides include nucleophilic substitution, elimination, reduction, and the formation of organometallics.COA of Formula: C7H5IO2

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

In 2019,Synthesis included an article by Singh, Anoop S.; Agrahari, Anand K.; Mishra, Nidhi; Singh, Mala; Tiwari, Vinod K.. Safety of 2-Iodobenzoic acid. The article was titled 《An Improved N-Acylation of 1H -Benzotriazole Using 2,2′-Dipyridyldisulfide and Triphenylphosphine》. The information in the text is summarized as follows:

A novel path was developed for the conversion of carboxylic acids into the corresponding N-acylbenzotriazoles by using 2,2′-dipyridyl disulfide/PPh3 in anhydrous dichloromethane in the presence of 1H-benzotriazole. Mild reaction conditions, short reaction time, easy in handling, wide substrate scope, availability of reagents involved and moreover avoiding the use of base made this protocol quite useful for the laboratory practices for N-acylbenzotriazole synthesis. The experimental process involved the reaction of 2-Iodobenzoic acid(cas: 88-67-5Safety of 2-Iodobenzoic acid)

2-Iodobenzoic acid(cas: 88-67-5) belongs to organic iodides. Alkyl iodides react at a faster rate than alkyl fluorides due to the weak C-I bond.Iodo alkanes participate in a variety of organic synthesis reactions, which include the Simmons–Smith reaction (cyclopropanation using iodomethane), Williamson ether synthesis, Wittig reaction, Grignard reaction, alkyl coupling reactions, and Wurtz reaction.Safety of 2-Iodobenzoic acid

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Synthetic Route of C7H7IIn 2019 ,《Suzuki-Miyaura reaction by heterogeneously supported Pd nanoparticles on thio-modified multi walled carbon nanotubes as efficient nanocatalyst》 was published in Polyhedron. The article was written by Veisi, Hojat; Nikseresht, Ahmad; Ahmadi, Nasim; Khosravi, Kaveh; Saeidifar, Fatemeh. The article contains the following contents:

The palladium (Pd) supported on thio-modified multi walled carbon nanotubes (MWCNTs/CC-SH/Pd) was utilized as a useful and reusable nanocatalyst in Suzuki-Miyaura coupling reactions. The catalyst was really efficient for the Suzuki-Miyaura reaction of aryl halides (Ar-I, Ar-Br, Ar-Cl) with phenylboronic acid and conversion was good in most cases. The aryl iodides and aryl bromides reactions take place at room temperature, while reaction of aryl chlorides occurred at temperature of 80°. The products yields ranged between70% and 96%. The catalyst indicated excellent constancy and could be recycled and reused up to four cycles with no considerable change in its catalytic behavior. After reading the article, we found that the author used 1-Iodo-4-methylbenzene(cas: 624-31-7Synthetic Route of C7H7I)

1-Iodo-4-methylbenzene(cas: 624-31-7) is used in wide range of medicals industrial applications as well as in pharmaceutical intermediates, polarizing films for Liquid Crystal Display (LCD) chemicals.Synthetic Route of C7H7I

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Computed Properties of C6H5IOIn 2020 ,《Chi-MIC-share: a new feature selection algorithm for quantitative structure-activity relationship models》 was published in RSC Advances. The article was written by Li, Yuting; Dai, Zhijun; Cao, Dan; Luo, Feng; Chen, Yuan; Yuan, Zheming. The article contains the following contents:

Quant. structure-activity relationship models are used in toxicol. to predict the effects of organic compounds on aquatic organisms. Common filter feature selection methods use correlation statistics to rank features, but this approach considers only the correlation between a single feature and the response variable and does not take into account feature redundancy. Although the minimal redundancy maximal relevance approach considers the redundancy among features, direct removal of the redundant features may result in loss of prediction accuracy, and cross-validation of training sets to select an optimal subset of features is time-consuming. In this paper, we describe the development of a feature selection method, Chi-MIC-share, which can terminate feature selection automatically and is based on an improved maximal information coefficient and a redundant allocation strategy. We validated Chi-MIC-share using three environmental toxicol. datasets and a support vector regression model. The results show that Chi-MIC-share is more accurate than other feature selection methods. We also performed a significance test on the model and analyzed the single-factor effects of the reserved descriptors. In the experiment, the researchers used many compounds, for example, 3-Iodophenol(cas: 626-02-8Computed Properties of C6H5IO)

3-Iodophenol(cas: 626-02-8) belongs to organic iodides. Generally organic iodides can be divided into two classes of alkyl iodides and aryl iodides. Typical reactions of alkyl iodides include nucleophilic substitution, elimination, reduction, and the formation of organometallics.Computed Properties of C6H5IOHalogenation of aromatic hydrocarbons is a very important reaction via an electrophilic aromatic substitution.

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

In 2022,Shi, Guanying; Dong, Zhenhua published an article in Molecules. The title of the article was 《Palladium Supported on Porous Organic Polymer as Heterogeneous and Recyclable Catalyst for Cross Coupling Reaction》.Name: 1-Chloro-3-iodobenzene The author mentioned the following in the article:

Palladium immobilized on an amide and ether functionalized porous organic polymer (Pd@AEPOP) is reported to be an effective heterogeneous catalyst for the Heck cross-coupling reaction of aryl iodides with styrene for the synthesis of diphenylethene derivatives Excellent yields can be obtained using a 0.8 mol% Pd catalyst loading under the optimized reaction condition. The heterogeneous Pd@AEPOP catalyst can also be applied on the Suzuki reaction and the reduction of nitroarene. In addition to this study using 1-Chloro-3-iodobenzene, there are many other studies that have used 1-Chloro-3-iodobenzene(cas: 625-99-0Name: 1-Chloro-3-iodobenzene) was used in this study.

1-Chloro-3-iodobenzene(cas: 625-99-0) belongs to organic iodides. Alkyl iodides react at a faster rate than alkyl fluorides due to the weak C-I bond.Iodo alkanes participate in a variety of organic synthesis reactions, which include the Simmons–Smith reaction (cyclopropanation using iodomethane), Williamson ether synthesis, Wittig reaction, Grignard reaction, alkyl coupling reactions, and Wurtz reaction.Name: 1-Chloro-3-iodobenzene

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com