Tag: 200-300

In 2022,Nandi, Shantanu; Mondal, Shuvam; Jana, Ranjan published an article in iScience. The title of the article was 《Chemo- and regioselective benzylic C(sp3)-H oxidation bridging the gap between hetero- and homogeneous copper catalysis》.Electric Literature of C7H5IO2 The author mentioned the following in the article:

An expedient synthesis of privileged seven-membered lactones, dibenzo[c,e]oxepin-5(7H)-one through a highly chemoselective benzylic C(sp3)-H activation was disclosed. Remarkably, the formation of widely explored six-membered lactone via C(sp2)-H activation was suppressed under the present conditions. The reaction proceeded smoothly on use of inexpensive metallic copper catalyst and di-tert-Bu peroxide (DTBP). Owing to the hazards of stoichiometric DTBP, further, a sustainable metallic copper/rose bengal dual catalytic system coupled with mol. oxygen replacing DTBP was developed. A 1,5-aryl migration through Smiles rearrangement was realized from the corresponding diaryl ether substrates instead of expected eight-membered lactones. The present methodol. was scalable, applied to the total synthesis of cytotoxic and neuroprotective natural product alterlactone. The catalyst was recyclable and the reaction could be performed in a copper bottle without any added catalyst. The experimental process involved the reaction of 2-Iodobenzoic acid(cas: 88-67-5Electric Literature of C7H5IO2)

2-Iodobenzoic acid(cas: 88-67-5) belongs to organic iodides. Generally organic iodides can be divided into two classes of alkyl iodides and aryl iodides. Typical reactions of alkyl iodides include nucleophilic substitution, elimination, reduction, and the formation of organometallics.Electric Literature of C7H5IO2

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

In 2022,Shirase, Yuto; Matsumoto, Akinobu; Lim, Kean Long; Tryk, Donald A.; Miyatake, Kenji; Inukai, Junji published an article in ACS Omega. The title of the article was 《Properties and Morphologies of Anion-Exchange Membranes with Different Lengths of Fluorinated Hydrophobic Chains》.Recommanded Product: 1-Chloro-3-iodobenzene The author mentioned the following in the article:

An anion-exchange electrolyte membrane, QPAF(C6)-4, polymerized with hydrophobic 1,4′-bis(3-chlorophenyl)perfluorohexane and hydrophilic 6,6′-(2,7-dichloro-9H-fluorene-9.9-diyl)bis(N,N-dimethylhexan-1-amine) is phys. flexible and chem. stable. The drawbacks are relatively large water swelling and lower OH- conductivity at higher water uptakes, which are considered to be due to the entanglement of the flexible hydrophobic structure of the membrane. In this study, a QPAF(C4)-4 membrane was newly synthesized with shortened hydrophobic fluoroalkyl chains. Unexpectedly, QPAF(C4)-4 showed a higher water uptake and a lower bulk/surface conductivity than QPAF(C6)-4 possibly due to the decrease in hydrophobicity with a smaller number of fluorine atoms. The thermal stability of QPAF(C4)-4 was higher than that of QAPF(C6)-4, possibly due to the rigidity of the QAPF(C4)-4 structure. A higher mech. strength of QAPF(C6)-4 than that of QPAF(C4)-4 could be explained by the larger interactions between mols., as shown in the UV-visible spectrum. The interactions of mols. were understood in more detail with d. functional theory calculations Both the chem. structures of the polymers and the arrangements of the polymers in the membranes were found to influence the membrane properties. In the experiment, the researchers used many compounds, for example, 1-Chloro-3-iodobenzene(cas: 625-99-0Recommanded Product: 1-Chloro-3-iodobenzene)

1-Chloro-3-iodobenzene(cas: 625-99-0) belongs to organic iodides. Organic iodides are used in veterinary products (Organic Iodide Powder) as a nutritional source of iodine. In the chemical industry, alkyl iodides serve as excellent alkylating agents and, specifically, methyl iodide is used as a methylating agent in the synthesis of various pharmaceutical drugs.Recommanded Product: 1-Chloro-3-iodobenzene

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

In 2022,Shen, Guodong; Lu, Qichao; Wang, Zeyou; Sun, Weiwei; Zhang, Yalin; Huang, Xianqiang; Sun, Manman; Wang, Zhiming published an article in Synthesis. The title of the article was 《Environmentally Friendly and Recyclable CuCl2 -Mediated C-S Bond Coupling Strategy Using DMEDA as Ligand, Base and Solvent》.Safety of 4-Iodobenzoic acid The author mentioned the following in the article:

An environment-friendly, recyclable and economic strategy was developed to synthesize diaryl chalcogenides by the CuCl2-catalyzed C-S bond-formation reaction via iodobenzenes and benzenethiols/1,2-diphenyldisulfanes using N,N’-dimethylethane-1,2-diamine (DMEDA) as ligand, base and solvent. For these reactions, especially the reactions of diiodobenzenes and aminobenzenethiols/disulfanediyldianilines, a range of substrates were compatible and gave the corresponding products in good to excellent yields. Both of the reagents in the catalytic system (CuCl2/DMEDA) were inexpensive, conveniently separable and recyclable for more than five cycles. The experimental part of the paper was very detailed, including the reaction process of 4-Iodobenzoic acid(cas: 619-58-9Safety of 4-Iodobenzoic acid)

4-Iodobenzoic acid(cas: 619-58-9) belongs to organic iodides. Generally organic iodides can be divided into two classes of alkyl iodides and aryl iodides. Safety of 4-Iodobenzoic acid Typical reactions of alkyl iodides include nucleophilic substitution, elimination, reduction, and the formation of organometallics.

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Rana, Rahul; Chang, Qing; Bassan, Jay; Chow, Sue; Hedley, David; Nitz, Mark published their research in ChemBioChem in 2021. The article was titled 《An Iodinated DAPI-Based Reagent for Mass Cytometry》.Recommanded Product: 516-12-1 The article contains the following contents:

Multiparametric single-cell anal. has seen dramatic improvements with the introduction of mass cytometry (MC) and imaging mass cytometry (IMC). These technologies expanded the number of biomarkers that can be identified simultaneously by using heavy-isotope-tagged antibody reagents. Small-mol. probes bearing heavy isotopes are emerging as addnl. useful functional reporters of cellular features. Realizing this, we explored the iodination of DAPI to produce a heavy-atom-substituted derivative of the commonly used fluorescent DNA stain. Although exhibiting a drastically reduced fluorescence emission profile, I-DAPI retains strong binding affinity for DNA. I-DAPI was used to detect cellular DNA in MC and IMC assays with comparable efficiency to known Ir-containing DNA intercalators. This work suggests repurposing well-known colorimetric stains through simple reactions could be an effective strategy to develop new, functional MC and IMC reagents. After reading the article, we found that the author used 1-Iodopyrrolidine-2,5-dione(cas: 516-12-1Recommanded Product: 516-12-1)

1-Iodopyrrolidine-2,5-dione(cas: 516-12-1) is used in the preparation of vinyl sulfones from olefins and benzenesulfinic acid. It acts as a source for I+ and involved in Hunsdiecker reactions for the conversion of cinnamic acids, and propiolic acids to the corresponding alfa-halostyrenes and 1-halo-1-alkynes respectively. Recommanded Product: 516-12-1

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

《Trichloroacetimidate-Triggered Expeditious and Novel Synthesis of N-Acylbenzotriazoles》 was written by Yadav, Mangal S.; Jaiswal, Manoj K.; Kumar, Sunil; Tiwari, Vinod K.. Synthetic Route of C7H5IO2 And the article was included in SynOpen in 2021. The article conveys some information:

A facile route for the synthesis of a diverse range of N-acylbenzotriazole derivatives from the corresponding carboxylic acids has been established through a carbonyl activation pathway. In this method, trichloroacetonitrile is performed as an effective reagent for an easy access of N-acylbenzotriazoles which was simply proceeded through the activation of carboxylic acids via in situ imidate formation in anhydrous 1,2-dichloroethane followed by addition of 1H-benzotriazole at 80° for 3-4 h. Easy handling, one-pot, and metal-free conditions demonstrate the notable merits of the devised protocol. The results came from multiple reactions, including the reaction of 2-Iodobenzoic acid(cas: 88-67-5Synthetic Route of C7H5IO2)

2-Iodobenzoic acid(cas: 88-67-5) belongs to organic iodides. The carbon-iodine bond is weaker than other carbon-halogen bonds due to the poor electronegative nature of the iodine atom. Synthetic Route of C7H5IO2 Alkyl iodides react at a faster rate than alkyl fluorides due to the weak C-I bond.

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

《Hierarchically hollow structured NiCo2S4@NiS for high-performance flexible hybrid supercapacitors》 was written by Qu, Guangmeng; Li, Chuanlin; Hou, Peiyu; Zhao, Gang; Wang, Xiao; Zhang, Xiaoli; Xu, Xijin. SDS of cas: 516-12-1 And the article was included in Nanoscale in 2020. The article conveys some information:

Hierarchical nanostructures with outstanding electrochem. properties and mech. stability are ideal for constructing flexible hybrid supercapacitors. Herein, hierarchically hollow NiCo2S4@NiS nanostructures were designed and synthesized by sulfurizing the hierarchical NiCo double hydroxides (DHs) coated with nickel hydroxide nanostructures on carbon fabrics (NiCo-DHs@Ni(OH)2/CF), which trigger excellent electrochem. performances. The NiCo2S4@NiS/CF exhibits a high specific capacity of 1314.0 C g-1 at a c.d. of 1 A g-1, and maintains the rate performance at about 79.2% of the initial capacity at 30 A g-1. The hybrid supercapacitors of NiCo2S4@NiS//AC display a high energy d. of 62.4 W h kg-1 at a power d. of 800 W kg-1 with a remarkable cycling stability (96.2% of initial capacitance after 5000 cycles) and robust mech. flexibility (no obvious decay of specific capacitance during various deformations). Consequently, NiCo2S4@NiS electrodes are expected to be a promising candidate for new smart energy storage devices with high security, stability and flexibility. The experimental part of the paper was very detailed, including the reaction process of 1-Iodopyrrolidine-2,5-dione(cas: 516-12-1SDS of cas: 516-12-1)

1-Iodopyrrolidine-2,5-dione(cas: 516-12-1) is used in the preparation of vinyl sulfones from olefins and benzenesulfinic acid. It acts as a source for I+ and involved in Hunsdiecker reactions for the conversion of cinnamic acids, and propiolic acids to the corresponding alfa-halostyrenes and 1-halo-1-alkynes respectively. SDS of cas: 516-12-1

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

《CuBr-Catalyzed One-Pot Three-Component Synthesis of Novel 2-(Carbazolyl)benzothiazoles》 was published in Synlett in 2020. These research results belong to Meesala, Ramu; Lee, Yean Kee; Arshad, Ahmad Saifuddin Mohamad; Abdullah, Iskandar; Mordi, Mohd Nizam; Abd Rahman, Noorsaadah. Product Details of 63069-48-7 The article mentions the following:

A facile synthesis of various 2-(carbazolyl)benzothiazoles were synthesized by one-pot CuBr-catalyzed three-component reactions of 2-iodoanilines, aryl aldehydes and elemental sulfur. Reaction exhibited a good functional group tolerance to produce the corresponding 2-(carbazolyl)benzothiazoles in good yields in the absence of any additive. In the experiment, the researchers used many compounds, for example, 4-Chloro-2-iodoaniline(cas: 63069-48-7Product Details of 63069-48-7)

4-Chloro-2-iodoaniline(cas: 63069-48-7) belongs to anime. Halogenation, in which one or more hydrogen atoms of an amine is replaced by a halogen atom, occurs with chlorine, bromine, and iodine, as well as with some other reagents, notably hypochlorous acid (HClO). With primary amines the reaction proceeds in two stages, producing N-chloro- and N,N-dichloro-amines, RNHCl and RNCl2, respectively. With tertiary amines, an alkyl group may be displaced by a halogen.Product Details of 63069-48-7

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

《Recyclable Heterogeneous Palladium-Catalyzed Carbonylative Cyclization of 2-Iodoanilines with Aryl Iodides Leading to 2-Arylbenzoxazinones》 was published in Synthesis in 2020. These research results belong to Xu, Zhaotao; Huang, Bin; Zhou, Zebiao; Cai, Mingzhong. Synthetic Route of C6H5ClIN The article mentions the following:

A highly efficient and practical heterogeneous palladium-catalyzed carbonylative coupling of 2-iodoanilines R-2-IC6H3NH2 (R = H, 4-Me, 5-Cl, 4-CN, etc.) with aryl iodides ArI (Ar = Ph, naphthalen-1-yl, thiophen-3-yl, etc.) has been developed. The reaction occurs smoothly in toluene at 110°C with N,N-diisopropylethylamine as base under carbon monoxide (5 bar) and offers a general and powerful tool for the construction of various valuable 2-arylbenzoxazinones I (R1 = H, 6-Me, 7-Cl, 6-CN, etc.) with excellent atom-economy, high functional group tolerance, good to high yields, and easy recyclability of the palladium catalyst. The reaction is the first example of heterogeneous palladium-catalyzed carbonylative coupling for the preparation of diverse 2-arylbenzoxazinones I from com. easily available 2-iodoanilines and aryl iodides. In the experiment, the researchers used 4-Chloro-2-iodoaniline(cas: 63069-48-7Synthetic Route of C6H5ClIN)

4-Chloro-2-iodoaniline(cas: 63069-48-7) belongs to anime. Amines can be classified according to the nature and number of substituents on nitrogen. Aliphatic amines contain only H and alkyl substituents. Aromatic amines have the nitrogen atom connected to an aromatic ring.Important amines include amino acids, biogenic amines, trimethylamine, and aniline. Inorganic derivatives of ammonia are also called amines, such as monochloramine (NClH2).Synthetic Route of C6H5ClIN

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

The author of 《3-(4-Iodophenyl)pentanedinitrile》 were Nanpo, Yuuki; Okuno, Tsunehisa. And the article was published in IUCrData in 2019. Application In Synthesis of 4-Iodobenzaldehyde The author mentioned the following in the article:

In the title pentanedinitrile derivative, C11H9IN2, the iodophenyl group is connected at the 3-position. The central propylene chain of the pentanedinitrile moiety contains one gauche conformation as a result of steric repulsion with the Ph ring. Intermol. close contacts in the crystal comprise a weak Csp3-H···N hydrogen bond and a C-I···N halogen bond. The experimental part of the paper was very detailed, including the reaction process of 4-Iodobenzaldehyde(cas: 15164-44-0Application In Synthesis of 4-Iodobenzaldehyde)

4-Iodobenzaldehyde(cas: 15164-44-0) is used in synthesis of 4-[2-(trimethylsilyl)ethynyl]benzaldehyde, 5,15-dimesityl-10-(3-[2-(trimethylsilyl)ethynyi]phenyl}-20-(4-iodophenyl)porphyrin, and 5,15-dimesityl-10-[3,5-bis{2-[4-(N,N’-difluoroboryl-1,9-dimethyidipyrrin-5-yl)-phenyl]ethynyl}phenyl]-20-(4-iodophenyl)porphyrin.Application In Synthesis of 4-Iodobenzaldehyde

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

The author of 《Synthesis and Bacteriostatic Activities of Modified Flutriafol Derivatives》 were Guo, Haoquan; Dong, Yuguo; Zhou, Xuliang; Lu, Xinyu; Zhu, Xiaojun; Que, Han; Wu, Zhipeng; Cheng, Kanghua; Gu, Xiaoli. And the article was published in ACS Omega in 2019. Application In Synthesis of Trimethylsulfoxonium iodide The author mentioned the following in the article:

This study aimed to evaluate the preservative ability of modified flutriafol derivatives against decay fungi. The bacteriostatic effect of flutriafol on Trichoderma viride was not efficient as expected. Flutriafol was modified as a parent substrate to improve its broad spectrum performance. Six triazole compounds were synthesized by Friedel-Crafts reaction, oxygen-sulfur-ylide reaction, and ring-opening addition reaction. The structures of the target products were determined by 1H NMR and MS. Antibacterial and antileakage tests were performed to optimize the most efficient agents among triazole target products. In the experiment, the researchers used Trimethylsulfoxonium iodide(cas: 1774-47-6Application In Synthesis of Trimethylsulfoxonium iodide)

Trimethylsulfoxonium iodide(cas: 1774-47-6) reacts with sodium hydride to prepare dimethyloxosulfonium methylide, which is used as a methylene-transfer reagent in synthetic chemistry. It is used to prepare ylide, which reacts with carbonyl compounds to get epoxides. Further, it reacts with alfa,beta-unsaturated esters to get cyclopropyl esters.Application In Synthesis of Trimethylsulfoxonium iodide

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com