Tag: 200-300

In 2019,ChemistrySelect included an article by Liu, Na; Tian, An-Qi; Ren, Zhi-Lin; Wang, Long. Related Products of 591-18-4. The article was titled 《Efficient Synthesis of Sulfonyl Diphenylsulfides Catalyzed via Cu-MOF of PCN-6’》. The information in the text is summarized as follows:

A metal organic framework of PCN-6′ was used, prepared from copper compound and triazine-2,4,6-triyl-benzoate (H3TATB) ligand, to catalyze the tandem reaction of disulfide with aryl iodide and sulfonyl chloride to synthesize of sulfonyl diphenylsulfides. A series of sulfonyl diphenylsulfide derivatives were synthesized with medium or high yields. The results came from multiple reactions, including the reaction of 1-Bromo-3-iodobenzene(cas: 591-18-4Related Products of 591-18-4)

1-Bromo-3-iodobenzene(cas: 591-18-4) has been used in the preparation of 1-(3′-bromophenyl)-3,3,4,4,5,5,6,6,7,7,8,8,9,9,10,10,10-heptadecafluorodec-1-ene and 1-(3′-bromophenyl)-3,3,4,4,5,5,6,6,7,7,8,8,8-tridecafluorooct-1-ene.Related Products of 591-18-4 Further, it is involved in the preparation of oxygen-tethered 1,6-enynes.

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Novoa, Nestor; Manzur, Carolina; Roisnel, Thierry; Kahlal, Samia; Saillard, Jean-Yves; Carrillo, David; Hamon, Jean-Rene published an article in 2021. The article was titled 《Nickel(II)-Based Building Blocks with Schiff Base Derivatives: Experimental Insights and DFT Calculations》, and you may find the article in Molecules.HPLC of Formula: 15854-87-2 The information in the text is summarized as follows:

We have recently reported a series of neutral square planar tridentate Schiff base (L) complexes of the general formula [(L)M(py)], showing relatively high first-order hyperpolarizabilities and NLO redox switching behavior. In the present study, new members of this family of compounds have been prepared with the objective to investigate their potential as building blocks in the on-demand construction of D-π-A push-pull systems. Namely, ternary nickel(II) building blocks of general formula [(LA/D)Ni(4-pyX)] (4-7), where LA/D stands for an electron accepting or donating dianionic O,N,O-tridentate Schiff base ligand resulting from the monocondensation of 2-aminophenol or its 4-substituted nitro derivative and β-diketones R-C(=O)CH2C(=O)CH3 (R = Me, anisyl, ferrocenyl), and 4-pyX is 4-iodopyridine or 4-ethynylpyridine, were synthesized and isolated in 60-78% yields. Unexpectedly, the Sonogashira cross-coupling reaction between the 4-iodopyridine derivative 6 and 4-ethynylpyridine led to the formation of the bis(4-pyridyl) acetylene bridged centrosym. dimer [{(LD)Ni}2(μ2-py-CΞC-py)] (8). Complexes 4-8 were characterized by elemental anal., FT-IR and NMR spectroscopy, single crystal X-ray diffraction and computational methods. In each compound, the four-coordinate Ni(II) metal ion adopts a square planar geometry with two nitrogen and two oxygen atoms as donors occupying trans positions. In the experiment, the researchers used many compounds, for example, 4-Iodopyridine(cas: 15854-87-2HPLC of Formula: 15854-87-2)

4-Iodopyridine(cas: 15854-87-2) is used as a reagent in the synthesis of indazolylamides as glucocorticoid receptor agonists. 4-Iodopyridine is a halogenated heterocycle that is a building block for proteomics research.HPLC of Formula: 15854-87-2

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Li, Jun; Yang, Yi; Liu, Yunxia; Liu, Qing; Zhang, Lizhi; Li, Xinjin; Dong, Yunhui; Liu, Hui published an article in 2021. The article was titled 《Palladium/Norbornene Catalyzed ortho Amination/Cyclization of Aryl Iodide: Process to 3-Methyl-indole Derivates and Controllable Reductive Elimination against the Second Amination》, and you may find the article in Organic Letters.Category: iodides-buliding-blocks The information in the text is summarized as follows:

A palladium/norbornene cooperative catalyzed selective C-H bond amination of aryl iodides was explored, providing an efficient tool for constructing benzocyclic mols. When ortho-substituted iodobenzene was involved, the C-H bond amination and following Heck cyclization efficiently delivered a 3-methyl-indole scaffold. On the other hand, we realized the controllable synthesis of monoaminated benzo-cyclobutanyl scaffold. The possible coordination of an installed terminal alkenyl group with palladium and steric hindrance were proposed to be responsible for the monoamination selectivity. In the experiment, the researchers used 4-Iodobenzaldehyde(cas: 15164-44-0Category: iodides-buliding-blocks)

4-Iodobenzaldehyde(cas: 15164-44-0) is used in synthesis of 4-[2-(trimethylsilyl)ethynyl]benzaldehyde, 5,15-dimesityl-10-(3-[2-(trimethylsilyl)ethynyi]phenyl}-20-(4-iodophenyl)porphyrin, and 5,15-dimesityl-10-[3,5-bis{2-[4-(N,N’-difluoroboryl-1,9-dimethyidipyrrin-5-yl)-phenyl]ethynyl}phenyl]-20-(4-iodophenyl)porphyrin.Category: iodides-buliding-blocks

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

da Rosa, Rafael; Grand, Lucie; Schenkel, Eloir P.; Sibelle Campos Bernardes, Lilian; Jacolot, Maiwenn; Popowycz, Florence published an article in 2021. The article was titled 《The Use of 5-Hydroxymethylfurfural towards Fine Chemicals: Synthesis and Direct Arylation of 5-HMF-Based Oxazoles》, and you may find the article in Synlett.Recommanded Product: 15854-87-2 The information in the text is summarized as follows:

The synthesis of 5-HMF-based oxazole compounds I [Ar = 4-MeC6H4, 3-FC6H4, 3-thienyl, etc.] were reported. While 5-HMF could be easily converted into the oxazole derivative through the Van Leusen reaction, the direct arylation step needed to access the final compounds was problematic at first. After optimization, a palladium-catalyzed procedure had been developed and used for the synthesis of a series of 33 derivatives This article reported an extension of the late-stage CH arylation reaction as an application to the oxazole platform derived from biosourced 5-HMF. The challenges in the preparation of the derivatives containing some electron-withdrawing substituents were overcome by the use of a palladium-free method. The results came from multiple reactions, including the reaction of 4-Iodopyridine(cas: 15854-87-2Recommanded Product: 15854-87-2)

4-Iodopyridine(cas: 15854-87-2) is used as a reagent in the synthesis of indazolylamides as glucocorticoid receptor agonists. 4-Iodopyridine is a halogenated heterocycle that is a building block for proteomics research.Recommanded Product: 15854-87-2

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

《Nickel-cobalt bimetallic sulfide NiCo2S4 nanostructures for a robust hydrogen evolution reaction in acidic media》 was written by Aftab, Umair; Tahira, Aneela; Mazzaro, Raffaello; Morandi, Vittorio; Ishaq Abro, Muhammad; Baloch, Muhammad Moazam; Yu, Cong; Ibupoto, Zafar Hussain. Application In Synthesis of 1-Iodopyrrolidine-2,5-dione And the article was included in RSC Advances in 2020. The article conveys some information:

In this study, we have designed a facile strategy by tailoring the concentration of precursors to successfully obtain nickel-cobalt bimetallic sulfide (NiCo2S4) using a simple hydrothermal method. The morphol. of the newly prepared NiCo2S4 comprised a mixture of microparticles and nanorods, which were few microns in dimension. The crystallinity of the composite sample was found to be excellent with a cubic phase. The sample that contained a higher amount of cobalt compared to nickel and produced single-phase NiCo2S4 exhibited considerably improved HER performance. The variation in the salt precursor concentration during the synthesis of a material is a simple methodol. to produce a scalable platinum-free catalyst for HER. The composite sample produced a c.d. of 10 mA cm-2 at an overpotential of 345 mV. Also, it exhibited a Tafel value of 60 mV dec-1, which predominantly ensured rapid charge transfer kinetics during HER. CN-21 was highly durable and stable for 30 h. The obtained results reveal that our developed NiCo2S4 catalyst has a high d. of active edges, and it is a non-noble metal catalyst for the hydrogen evolution reaction. The present findings provide an alternative strategy and an active nonprecious material for the development of energy-related applications. The experimental process involved the reaction of 1-Iodopyrrolidine-2,5-dione(cas: 516-12-1Application In Synthesis of 1-Iodopyrrolidine-2,5-dione)

1-Iodopyrrolidine-2,5-dione(cas: 516-12-1) is used in the preparation of vinyl sulfones from olefins and benzenesulfinic acid. It acts as a source for I+ and involved in Hunsdiecker reactions for the conversion of cinnamic acids, and propiolic acids to the corresponding alfa-halostyrenes and 1-halo-1-alkynes respectively. Application In Synthesis of 1-Iodopyrrolidine-2,5-dione

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

《Benzene-1,3,5-triyl Triformate (TFBen)-Promoted Palladium-Catalyzed Carbonylative Synthesis of 2-Oxo-2,5-dihydropyrroles from Propargyl Amines》 was published in Organic Letters in 2020. These research results belong to Ying, Jun; Le, Zhengjie; Wu, Xiao-Feng. Formula: C7H7I The article mentions the following:

In this letter, we developed a palladium-catalyzed procedure for the cyclocarbonylation of propargyl amines. Benzene-1,3,5-triyl triformate (TFBen) has been explored as the CO source and also as the key promotor. Various substituted 2-oxo-dihydropyrroles were produced in a facile manner in good yields (up to 90%).1-Iodo-4-methylbenzene(cas: 624-31-7Formula: C7H7I) was used in this study.

1-Iodo-4-methylbenzene(cas: 624-31-7) undergoes Suzuki-Miyaura coupling reaction with phenylboronic acid catalyzed by (Ni,Mg)3Si2O5(OH)4 solid-solution nanotubes loaded with palladium.Formula: C7H7I

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

The author of 《Design and synthesis of a novel banana-shaped functional molecule via double cross-coupling》 were Yang, Bingchuan; Shen, Guodong; Huang, Xianqiang; Liu, Rutao. And the article was published in Molecules in 2019. Safety of 4-Iodobenzoic acid The author mentioned the following in the article:

A novel banana-shaped mol. using 2,8-dimethyl-6H,12H-5,11-methanodibenzo[b,f][1,5]diazocine (Troger’s base) as bent-core was synthesized via double carbon-carbon cross-coupling reaction. The double Sonogashira cross-coupling reaction was optimized by using Pd(PPh3)2Cl2 as catalyst, CuI as cocatalyst and diisopropylamine as base in place of triethylamine. The structure of this compound was confirmed by 1H-NMR, 13C-NMR, Fourier transform IR (FT-IR) spectroscopy and mass spectrometry. After reading the article, we found that the author used 4-Iodobenzoic acid(cas: 619-58-9Safety of 4-Iodobenzoic acid)

4-Iodobenzoic acid(cas: 619-58-9) belongs to organic iodides. Generally organic iodides can be divided into two classes of alkyl iodides and aryl iodides. Typical reactions of alkyl iodides include nucleophilic substitution, elimination, reduction, and the formation of organometallics.Safety of 4-Iodobenzoic acidHalogenation of aromatic hydrocarbons is a very important reaction via an electrophilic aromatic substitution.

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

The author of 《A study of donor-acceptor interaction in halogen bonded complexes of N-iodosuccinimide by 14N NQR》 were Apih, T.; Gregorovic, A.; Zagar, V.; Seliger, J.. And the article was published in Chemical Physics in 2019. Application In Synthesis of 1-Iodopyrrolidine-2,5-dione The author mentioned the following in the article:

Some halogen bonded complexes of N-iodosuccinimide (NIS) with the nitrogen atoms at the donor and acceptor positions have been investigated by 14N NQR (NQR) spectroscopy. The data are analyzed in view of the change of the principal values of the quadrupole coupling tensor produced by halogen bonding. The results show that the deformation of the nitrogen electron orbitals is in the presently studied halogen bonded systems comparable to the one observed in strong hydrogen bonded systems. The order in which the strength of the halogen bond acceptor increases is determined A possible iodine displacement to a position, which is closer to the acceptor nitrogen atom than to the donor nitrogen atom may occur in the complex NIS-(3-picoline). In all studied complexes the deformation of the nitrogen electron orbitals caused by the halogen bond decreases with increasing temperature at both the donor and acceptor nitrogen positions. In the experiment, the researchers used 1-Iodopyrrolidine-2,5-dione(cas: 516-12-1Application In Synthesis of 1-Iodopyrrolidine-2,5-dione)

1-Iodopyrrolidine-2,5-dione(cas: 516-12-1) is used in the preparation of vinyl sulfones from olefins and benzenesulfinic acid. It acts as a source for I+ and involved in Hunsdiecker reactions for the conversion of cinnamic acids, and propiolic acids to the corresponding alfa-halostyrenes and 1-halo-1-alkynes respectively. Application In Synthesis of 1-Iodopyrrolidine-2,5-dione

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

The author of 《Ruthenium(II)-catalyzed chemoselective deacylative annulation of 1,3-diones with sulfoxonium ylides via C-C bond activation》 were Wen, Si; Lv, Weiwei; Ba, Dan; Liu, Jing; Cheng, Guolin. And the article was published in Chemical Science in 2019. Related Products of 1774-47-6 The author mentioned the following in the article:

The first successful example of deacylative annulation of 1,3-diones RC(O)CH2C(O)R1 (R = Ph, 4-methoxyphenyl, furan-2-yl, etc.; R1 = Ph, thiophen-2-yl, furan-2-yl, etc.) with sulfoxonium ylides R2C(O)C(R3)=S(O)(CH3)2 (R2 = thiophen-2-yl, naphthalen-2-yl, 2-phenylethenyl, etc.; R3 = H, Ph) was achieved through Ru(II)-catalyzed C-C bond activation. The excellent chemoselectivity and broad substrate scope render this method a practical and versatile approach for the preparation of (hetero)aryl and alkenyl substituted furans I, which are valuable units in many biol. active compounds and functional materials. A preliminary mechanistic study reveals that this process involves a deacylative α-ruthenation to generate key alkyl Ru(II) intermediates with the release of a benzoic acid fragment. In the experiment, the researchers used many compounds, for example, Trimethylsulfoxonium iodide(cas: 1774-47-6Related Products of 1774-47-6)

Trimethylsulfoxonium iodide(cas: 1774-47-6) is a sulfoxonium salt. It is used to generate dimethyloxosulfonium methylide by reaction with sodium hydride. The latter compound is used as a methylene-transfer reagent, and is used to prepare epoxides.Related Products of 1774-47-6

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

In 2019,ACS Catalysis included an article by Trillo, Paz; Adolfsson, Hans. Recommanded Product: 4-Iodobenzoic acid. The article was titled 《Direct Catalytic Reductive N-Alkylation of Amines with Carboxylic Acids: Chemoselective Enamine Formation and further Functionalizations》. The information in the text is summarized as follows:

Direct reductive N-alkylation of secondary amines with carboxylic acids using molybdenum hexacarbonyl (5 mol %) as catalyst and diethoxymethylsilane as reducing agent generate enamines in a straightforward fashion in high yields. The formed enamines are without the need for isolation or purification further reacted with trimethylsilyl cyanide in the same reaction flask to yield α-amino nitriles in good yields. In the optimized reaction conditions equimolar amounts of carboxylic acid and amine are reacted under neat conditions, and a catalytic amount of trifluoroethanol (0.1 mol %) is added along with TMSCN for the cyanation step. The reductive N-alkylation reaction is demonstrated to be highly chemoselective, tolerating a multitude of different functional groups present in the starting carboxylic acids and amines. The reaction is scalable and the generated α-amino nitriles are converted to other useful compounds, e.g., α-amino acids or amino-tetrazoles. In addition, the intermediate enamines are further transformed into triazolines, sulfonylformamidines, pyrimidinediones, and TMS-propargylamines, resp., in high yields under mild reaction conditions. Benzoic acids react with secondary amines under similar conditions to give tertiary amines in high yields, and using this methodol., the biol. active compound Piribedil was isolated in 80% yield in a direct one-pot reaction setup.4-Iodobenzoic acid(cas: 619-58-9Recommanded Product: 4-Iodobenzoic acid) was used in this study.

4-Iodobenzoic acid(cas: 619-58-9) belongs to organic iodides. The carbon-iodine bond is weaker than other carbon-halogen bonds due to the poor electronegative nature of the iodine atom. Organic iodides can be alkyl, alkenyl, or alkynyl, and all of them are very reactive toward with many kinds of nucleophiles.Recommanded Product: 4-Iodobenzoic acid

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com