Tag: 200-300

HPLC of Formula: 625-99-0In 2019 ,《A palladium-catalyzed three-component cascade S-transfer reaction in ionic liquids》 was published in Green Chemistry. The article was written by Li, Jianxiao; Wu, Yaodan; Hu, Miao; Li, Can; Li, Meng; He, Dandan; Jiang, Huanfeng. The article contains the following contents:

A palladium-catalyzed three component cascade S-transfer reaction of acetylenic oximes RCCC(R1)=NOH (R = Ph, cyclopropyl, cyclohexyl, thiophen-3-yl, etc.; R1 = Me, Ph, cyclohexyl, etc.) with aryl halides ArI (Ar = 4-methylphenyl, 4-methoxyphenyl, naphthalen-2-yl, thiophen-2-yl, etc.) using readily available Na2S2O3 as an odorless sulfenylation reagent under aerobic conditions in ionic liquids was described. The present protocol features environmental friendliness, good functional group compatibility, odorless sulfenylation reagents, without any ligand or additive, and excellent atom and step economy. Remarkably, this cascade procedure will bring further late-stage modification for the construction of structurally complex isoxazole scaffolds I in synthetic and pharmaceutical chem. In the experiment, the researchers used many compounds, for example, 1-Chloro-3-iodobenzene(cas: 625-99-0HPLC of Formula: 625-99-0)

1-Chloro-3-iodobenzene(cas: 625-99-0) belongs to organic iodides. The carbon-iodine bond is weaker than other carbon-halogen bonds due to the poor electronegative nature of the iodine atom. Organic iodides can be alkyl, alkenyl, or alkynyl, and all of them are very reactive toward with many kinds of nucleophiles.HPLC of Formula: 625-99-0

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

In 2022,Du, Yiming; Chen, Shuxin; Huang, Ao; Chen, Yihan; Liu, Yun-Lin; Song, Gaopeng; Tang, Ri-Yuan; Xu, Hanhong; Yao, Guangkai; Li, Zhaodong published an article in Organic Letters. The title of the article was 《Diversity-Oriented Synthesis of Fluoromethylated Arenes via Palladium-Catalyzed C-H Fluoromethylation of Aryl Iodides》.Computed Properties of C7H5IO The author mentioned the following in the article:

Herein the first versatile and expeditious method for the site-selective C-H fluoromethylation of aryl iodides ArI (Ar = 2-methylphenyl, 6-chloro-2-methylpyridin-3-yl, 2H-1,3-benzodioxol-5-yl, etc.) via Pd/NBE cooperative catalysis, which could work as a robust toolbox for the diversity-oriented synthesis (DOS) of fluoromethylated arenes, e.g., tert-Bu (E)-3-(2,4-bis(fluoromethyl)-6-methoxypyridin-3-yl)acrylate has been reported. This methodol. features the use of low-cost industrial raw material CH2IF as fluoromethyl source, excellent functional group tolerance and broad ipso terminations scope, and could be expanded to the late-stage modification of biorelevant mols. In the experiment, the researchers used many compounds, for example, 4-Iodobenzaldehyde(cas: 15164-44-0Computed Properties of C7H5IO)

4-Iodobenzaldehyde(cas: 15164-44-0) is used in synthesis of 4-[2-(trimethylsilyl)ethynyl]benzaldehyde, 5,15-dimesityl-10-(3-[2-(trimethylsilyl)ethynyi]phenyl}-20-(4-iodophenyl)porphyrin, and 5,15-dimesityl-10-[3,5-bis{2-[4-(N,N’-difluoroboryl-1,9-dimethyidipyrrin-5-yl)-phenyl]ethynyl}phenyl]-20-(4-iodophenyl)porphyrin.Computed Properties of C7H5IO

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Zou, Zhenlei; Li, Heyin; Huang, Mengjun; Zhang, Weigang; Zhi, Sanjun; Wang, Yi; Pan, Yi published an article in 2021. The article was titled 《Electrochemical-Promoted Nickel-Catalyzed Oxidative Fluoroalkylation of Aryl Iodides》, and you may find the article in Organic Letters.Product Details of 619-58-9 The information in the text is summarized as follows:

This work describes a general strategy for metal-catalyzed cross-coupling of fluoroalkyl radicals with aryl halides ArX (Ar = biphenyl-4-yl, benzothiophen-3-yl, benzodioxol-5-yl, etc.; X = Br, I) under electrochem. conditions. The contradiction between anodic oxidation of fluoroalkyl sulfinates NaSO2CF2H, NaSO2CH2F and cathodic reduction of low-valent nickel catalysts can be well addressed by paired electrolysis, allowing for direct introduction of fluorinated functionalities into aromatic systems. After reading the article, we found that the author used 4-Iodobenzoic acid(cas: 619-58-9Product Details of 619-58-9)

4-Iodobenzoic acid(cas: 619-58-9) belongs to organic iodides. Alkyl iodides react at a faster rate than alkyl fluorides due to the weak C-I bond.Iodo alkanes participate in a variety of organic synthesis reactions, which include the Simmons–Smith reaction (cyclopropanation using iodomethane), Williamson ether synthesis, Wittig reaction, Grignard reaction, alkyl coupling reactions, and Wurtz reaction.Product Details of 619-58-9

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

The author of 《Ultra-deep desulfurization of FCC gasoline: reactive adsorption strategy》 were Tao, Y.. And the article was published in Hydrocarbon Processing in 2019. Application of 516-12-1 The author mentioned the following in the article:

This article describes the reactive adsorption strategy of ultra-deep desulfurization of FCC gasoline. Com. gasoline is mixed by different cuts from processes such as fluid catalytic cracking, reforming, isomerization, and alkylation. Generally, due to the prehydrotreated feedstock for reforming, isomerization and alkylation units, gasoline from these units contains little or no sulfur.1-Iodopyrrolidine-2,5-dione(cas: 516-12-1Application of 516-12-1) was used in this study.

1-Iodopyrrolidine-2,5-dione(cas: 516-12-1) is used in the preparation of vinyl sulfones from olefins and benzenesulfinic acid. It acts as a source for I+ and involved in Hunsdiecker reactions for the conversion of cinnamic acids, and propiolic acids to the corresponding alfa-halostyrenes and 1-halo-1-alkynes respectively. Application of 516-12-1

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

The author of 《Electrochemical Fluorocyclization of N-Allylcarboxamides to 2-Oxazolines by Hypervalent Iodine Mediator》 were Haupt, John D.; Berger, Michael; Waldvogel, Siegfried R.. And the article was published in Organic Letters in 2019. Reference of 1-Iodo-4-methylbenzene The author mentioned the following in the article:

A resource saving protocol for the synthesis of 5-fluoromethyl-2-oxazolines by using electrochem. has been realized. Thereby, a hypervalent iodine species I(III) is generated by anodic oxidation in the presence of Et3N·5HF and mediates the cyclization of N-allylcarboxamide to 5-fluoromethyl-2-oxazoline. This method allows application to various substrates furnishing the 2-oxazolines with yields up to 68%. The protocol is easy to conduct under constant current conditions offering a sustainable alternative over conventional reagent-based pathways. The experimental part of the paper was very detailed, including the reaction process of 1-Iodo-4-methylbenzene(cas: 624-31-7Reference of 1-Iodo-4-methylbenzene)

1-Iodo-4-methylbenzene(cas: 624-31-7) undergoes Suzuki-Miyaura coupling reaction with phenylboronic acid catalyzed by (Ni,Mg)3Si2O5(OH)4 solid-solution nanotubes loaded with palladium.Reference of 1-Iodo-4-methylbenzene

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

In 2019,ChemPlusChem included an article by Sivalingam, Soumya; Debsharma, Kingshuk; Dasgupta, Ayan; Sankararaman, Sethuraman; Prasad, Edamana. Formula: C10H7I. The article was titled 《Effect of Slip-Stack Self-Assembly on Aggregation-Induced Emission and Solid-State Luminescence in 1,3-Diarylpropynones》. The information in the text is summarized as follows:

Co-facial stacking can result in aggregation-caused quenching (ACQ) in conjugated organic luminogens. This study provides an attractive ‘slip-stack’ self-assembly approach which can eliminate the occurrence of ACQ. The obtained results from steady-state and time-resolved optical studies, along with X-ray diffraction and computational studies demonstrate aggregation-induced emission enhancement (AIEE) of a donor-π-acceptor based 1,3-diarylpropynone, namely 1-(naphthalenyl)-3-(pyren-1-yl)prop-2-yn-1-one (PYNAP). Unlike the monomer, which exhibits poor photoluminescence in solution (Φf = 2% in ACN), the twisted manifold of PYNAP allows the orientation of the mols. in a slip-stack fashion during the course of aggregation, which not only avoids a direct co-facial arrangement, but also induces augmented rigidity, leading to restricted intramol. rotation (RIR) and enhanced emission quantum yield (Φf = 5% in ACN/H2O). The aggregation behavior of PYNAP’s congener, 1-phenyl-3-(pyren-1-yl)prop-2-yn-1-one (PYPH) reinforces the hypothesis that slip-stack assembly is a useful strategy for AIEE in polycyclic hydrocarbon luminogens. In the experiment, the researchers used many compounds, for example, 1-Iodonaphthalene(cas: 90-14-2Formula: C10H7I)

1-Iodonaphthalene(cas: 90-14-2) is one of organic iodides. Alkyl iodides react at a faster rate than alkyl fluorides due to the weak C-I bond. Iodo alkanes participate in a variety of organic synthesis reactions, which include the Simmons–Smith reaction (cyclopropanation using iodomethane), Williamson ether synthesis, Wittig reaction, Grignard reaction, alkyl coupling reactions, and Wurtz reaction.Formula: C10H7I

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

《Palladium-Catalyzed Cascade Carbonylative Cyclization Reaction of Trifluoroacetimidoyl Chlorides and 2-Iodoanilines: Toward 2-(Trifluoromethyl)quinazolin-4(3H)-ones Synthesis》 was written by Yang, Hefei; Wang, Le-Cheng; Wang, Wei-Feng; Chen, Zhengkai; Wu, Xiao-Feng. Related Products of 63069-48-7This research focused ontrifluoroacetimidoyl chloride iodoaniline palladium catalyst cascade cyclization; trifluoromethyl quinazolinone preparation. The article conveys some information:

A palladium-catalyzed cascade carbonylative/cyclization reaction for the synthesis of 2-(trifluoromethyl)quinazolin-4(3H)-ones was achieved. The transformation utilizes readily available 2-iodoanilines and trifluoroacetimidoyl chlorides as the starting reagents, enabling a simple and convenient access to pharmaceutically significant quinazolin-4(3H)-one derivatives In the part of experimental materials, we found many familiar compounds, such as 4-Chloro-2-iodoaniline(cas: 63069-48-7Related Products of 63069-48-7)

4-Chloro-2-iodoaniline(cas: 63069-48-7) belongs to anime. Many important products require amines as part of their syntheses. Methylamine is utilized in the production of the analgesic meperidine (trade name Demerol) and the photographic developer Metol (trademark), and dimethylamine is used in the synthesis of the antihistamine diphenhydramine (trade name Benadryl), the solvent dimethylformamide (DMF), and the rocket propellant 1,1-dimethylhydrazine. The synthesis of the insect repellent N,N-diethyl-m-toluamide (DEET) incorporates diethylamine while that of the synthetic fibre Kevlar requires aromatic amines.Related Products of 63069-48-7

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

《Dimethyl 2-{[2-(2-methoxy-1-methoxycarbonyl-2- oxoethyl)-4,5,7-trimethoxy-3-(2,4,5-trimethoxyphenyl) -2,3-dihydro-1H-inden-1-yl]methyl}malonate》 was written by Boichenko, Maksim A.; Chagarovskiy, Alexey O.; Rybakov, Victor B.; Trushkov, Igor V.; Ivanova, Olga A.. Recommanded Product: 1774-47-6This research focused ontrimethoxyphenyl cyclopropanediester dimerization; dimethyl trimethoxyphenyl trimethoxyindanyl malonate preparation. The article conveys some information:

A simple synthetic approach to di-Me 2-{[2-(2-methoxy-1-methoxycarbonyl-2-oxoethyl) -4,5,7-trimethoxy-3-(2,4,5-trimethoxyphenyl)-2,3-dihydro-1H-inden-1-yl]methyl}malonate was developed, based on a B(C6F5)3-induced domino dimerization of 2-(2,4,5-trimethoxyphenyl) cyclopropane-1,1-diester. The experimental process involved the reaction of Trimethylsulfoxonium iodide(cas: 1774-47-6Recommanded Product: 1774-47-6)

Trimethylsulfoxonium iodide(cas: 1774-47-6) reacts with sodium hydride to prepare dimethyloxosulfonium methylide, which is used as a methylene-transfer reagent in synthetic chemistry. It is used to prepare ylide, which reacts with carbonyl compounds to get epoxides.Recommanded Product: 1774-47-6

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Formula: C2H4I2In 2017 ,《Synthesis of 1,2-Bis(trifluoromethylthio)arenes via Aryne Intermediates》 was published in Organic Letters. The article was written by Mesgar, Milad; Daugulis, Olafs. The article contains the following contents:

A general method for synthesis of 1,2-bis-trifluoromethylthioarenes has been developed. Arynes generated from silylaryl triflates or halides react with bis(trifluoromethyl)disulfide to afford 1,2-bis-trifluoromethylthioarenes. Aryl, alkyl, ester, halide, and methoxy functionalities are compatible with reaction conditions. Use of bis(perfluoroaryl)disulfides gave moderate yields of aryne disulfenylation or cyclization to fluorinated dibenzothiophenes. After reading the article, we found that the author used 1,2-Diiodoethane(cas: 624-73-7Formula: C2H4I2)

1,2-Diiodoethane(cas: 624-73-7) is one of organic iodides. The carbon-iodine bond is weaker than other carbon-halogen bonds due to the poor electronegative nature of the iodine atom. In general, organic iodides are light-sensitive and turn yellow during storage, owing to the formation of iodine. Organic iodides can be alkyl, alkenyl, or alkynyl, and all of them are very reactive toward with many kinds of nucleophiles.Formula: C2H4I2

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Reference of 1,2-DiiodoethaneIn 2016 ,《Ligand-Controlled Monoselective C-Aryl Glycoside Synthesis via Palladium-Catalyzed C-H Functionalization of N-Quinolyl Benzamides with 1-Iodoglycals》 appeared in Organic Letters. The author of the article were Liu, Minglong; Niu, Youhong; Wu, Yan-Fen; Ye, Xin-Shan. The article conveys some information:

A monoselective synthesis of aryl-C-Δ1,2-glycosides, e.g. I, from 1-iodoglycals via palladium-catalyzed ortho-C-H activation of N-quinolyl benzamides has been developed. An amino acid derivative was used as a crucial ligand to improve the yield and monoselectivity of the coupling reaction. The utility of this protocol was demonstrated by a concise synthesis of key moieties of some natural products.1,2-Diiodoethane(cas: 624-73-7Reference of 1,2-Diiodoethane) was used in this study.

1,2-Diiodoethane(cas: 624-73-7) is one of organic iodides. The carbon-iodine bond is weaker than other carbon-halogen bonds due to the poor electronegative nature of the iodine atom. In general, organic iodides are light-sensitive and turn yellow during storage, owing to the formation of iodine. Organic iodides can be alkyl, alkenyl, or alkynyl, and all of them are very reactive toward with many kinds of nucleophiles.Reference of 1,2-Diiodoethane

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com