Tag: 200-300

Wei, Huiqin; Wu, Mei published an article in 2021. The article was titled 《Photocatalytic synthesis of phenols mediated by visible light using KI as catalyst》, and you may find the article in Tetrahedron Letters.Quality Control of 3-Iodophenol The information in the text is summarized as follows:

A transition-metal-free hydroxylation of iodoarenes to afford substituted phenols was described. The reaction was promoted by KI under white LED light irradiation and uses atm. oxygen as oxidant. By the use of triethylamine as base and solvent, the corresponding phenols are obtained in moderate to good yields. Mechanistic studies suggested that KI and catalysis synergistically promote the cleavage of C-I bond to form free aryl radicals. In the experimental materials used by the author, we found 3-Iodophenol(cas: 626-02-8Quality Control of 3-Iodophenol)

3-Iodophenol(cas: 626-02-8) belongs to organic iodides. Generally organic iodides can be divided into two classes of alkyl iodides and aryl iodides. Typical reactions of alkyl iodides include nucleophilic substitution, elimination, reduction, and the formation of organometallics.Quality Control of 3-Iodophenol

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Wu, Pingfan; Wang, Yu; Chen, Weizhou; Hu, Xunliang; Huang, Bo; Xiao, Zicheng published an article in 2021. The article was titled 《Structural and Magnetical Studies of Mixed-Valence Hexavanadate Hybrids: How Organic Ligands Affect the Magnetism of Polyoxometalates?》, and you may find the article in Inorganic Chemistry.COA of Formula: C7H5IO2 The information in the text is summarized as follows:

In this Communication, authors illustrate the influence of organic ligands on magnetic structure and behavior by employing a mixed-valence Lindqvist-type hexavanadate as a research platform. Through covalently attaching to different halogen-containing organic ligands, the derived hybrid materials have different magnetism compared to their parent structure. Single-crystal x-ray analyses show that the introduction of organic ligands can modify the crystal packing manners of the derivatives, leading to further changes of the interaction between magnetic units. This work demonstrates that organic functionalization can remarkably affect the magnetism of polyoxometalates by adjusting the distance and location of the magnetic fractions. The results came from multiple reactions, including the reaction of 4-Iodobenzoic acid(cas: 619-58-9COA of Formula: C7H5IO2)

4-Iodobenzoic acid(cas: 619-58-9) belongs to organic iodides. Generally organic iodides can be divided into two classes of alkyl iodides and aryl iodides. Typical reactions of alkyl iodides include nucleophilic substitution, elimination, reduction, and the formation of organometallics.COA of Formula: C7H5IO2

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Li, Jing; Kwon, Eunsang; Lear, Martin J.; Hayashi, Yujiro published an article in 2021. The article was titled 《Halogen Bonding of N-Halosuccinimides with Amines and Effects of Broensted Acids in Quinuclidine-Catalyzed Halocyclizations》, and you may find the article in Helvetica Chimica Acta.HPLC of Formula: 516-12-1 The information in the text is summarized as follows:

An arguable expectation in halogen chem. is that an amine will react oxidatively with an N-halosuccinimide (NXS) to form an N-halogenated species bearing a covalent N-X bond. While likely for NCS under most conditions, we find this expectation simply not true for NIS and largely inaccurate for NBS. Herein, we disclose evidence through systematic NMR and X-ray studies that non-covalent halogen bonded amine complexes of NIS predominate over covalent N-halogenated species, even with primary and secondary amines. For example, during the catalytic electrophilic halocyclization of gem-disubstituted alkenes by cinchona-like amines, the quinuclidine complexes of NIS and NBS display lower reactivity than their parent N-halosuccinamides and require the presence of an appropriate Broensted acid. Specifically, a Broensted acid and quinuclidine jointly catalyze the halo-cycloetherification of γ-alkenyl alcs. with NIS or NBS, while only quinuclidine acts as a catalyst in the halolactonization of γ-alkenoic acids. Although our evidence confirms a transient N-halogenated quaternary ammonium salt as the halonium species, it is important to note that NIS predominantly forms ‘off-cycle’ halogen bonded amine complexes in solution1-Iodopyrrolidine-2,5-dione(cas: 516-12-1HPLC of Formula: 516-12-1) was used in this study.

1-Iodopyrrolidine-2,5-dione(cas: 516-12-1) is used in the preparation of vinyl sulfones from olefins and benzenesulfinic acid. It acts as a source for I+ and involved in Hunsdiecker reactions for the conversion of cinnamic acids, and propiolic acids to the corresponding alfa-halostyrenes and 1-halo-1-alkynes respectively. HPLC of Formula: 516-12-1

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Shamsa, Farzaneh; Motavalizadehkakhky, Alireza; Zhiani, Rahele; Mehrzad, Jamshid; Hosseiny, Malihe Sadat published their research in RSC Advances in 2021. The article was titled 《ZnO nanoparticles supported on dendritic fibrous nanosilica as efficient catalysts for the one-pot synthesis of quinazoline-2,4(1H,3H)-diones》.HPLC of Formula: 63069-48-7 The article contains the following contents:

The transmutation of waste into valuable materials has a special place in green chem. Herein, we report the preparation of quinazoline-2,4(1H,3H)-diones from 2-iodoaniline, isocyanides, and carbon dioxide in the presence of ZnO NPs stably placed on the surface of dendritic fibrous nanosilica by cellulose (DFNS/cellulose-ZnO) as a catalyst. This is a great economic strategy to create three bonds in a one-pot multicomponent reaction step employing functional groups. To prepare the catalyst, the dendritic fibrous nanosilica surface was first activated using cellulose as a substrate to support ZnO NPs. Cellulose acts as a stabilizing and reducing agent for the ZnO nanocatalyst and eliminates the need for a reducing agent. The structure of the prepared DFNS/cellulose-ZnO was examined by various methods, including thermogravimetric anal. (TGA), X-ray diffraction (XRD), SEM, transmission electron microscopy (TEM), XPS, and inductively coupled plasma (ICP). The largest amount of quinazoline-2,4(1H,3H)-diones was obtained under ideal situations in the presence of 5 mg of DFNS/cellulose-ZnO under carbon dioxide (1 atm) utilizing a balloon set at 70°C for 3 h. The substance was reused for ten consecutive runs and the quinazoline-2,4(1H,3H)-dione content was more than 92% each time. This indicates the potential for application in the green and economic production of quinazoline-2,4(1H,3H)-diones, especially from low-cost feedstocks. The experimental part of the paper was very detailed, including the reaction process of 4-Chloro-2-iodoaniline(cas: 63069-48-7HPLC of Formula: 63069-48-7)

4-Chloro-2-iodoaniline(cas: 63069-48-7) belongs to anime. The reaction of alkyl halides, R―X, where X is a halogen, or analogous reagents with ammonia (or amines) is useful with certain compounds. Not all alkyl halides are effective reagents; the reaction is sluggish with secondary alkyl groups and fails with tertiary ones. Its usefulness is largely confined to primary alkyl halides (those having two hydrogen atoms on the reacting site).HPLC of Formula: 63069-48-7

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Xu, Jia-Cheng; Yin, Yi-Zhuo; Han, Zhi-Yong published their research in Organic Letters in 2021. The article was titled 《Asymmetric Counteranion Directed Catalytic Heck/Tsuji-Trost Annulation of Aryl Iodides and 1,3-Dienes》.COA of Formula: C6H5ClIN The article contains the following contents:

A chiral anion-mediated asym. Heck/Tsuji-Trost reaction of aryl iodides and 1,3-dienes was presented. Chiral indoline derivatives I [R1 = H, 5-OMe, 6-Me, etc.; R2 = Ms, Ts, Ns; R3 = Me, Ph, 2-naphthyl, etc.] could be afforded with remarkably higher yields and enantioselectivities than our previous chiral ligand-based method. Silver carbonate was employed as both base and halide scavenger to ensure fast and recyclable exchange of the catalytic amount of chiral anions. Fast salt metathesis, as well as the acceleration effect of the chiral anion, could both benefit the stereocontrol of the reaction. In the experimental materials used by the author, we found 4-Chloro-2-iodoaniline(cas: 63069-48-7COA of Formula: C6H5ClIN)

4-Chloro-2-iodoaniline(cas: 63069-48-7) belongs to anime. Reaction with nitrous acid (HNO2), which functions as an acylating agent that is a source of the nitrosyl group (―NO), converts aliphatic primary amines to nitrogen and mixtures of alkenes and alcohols corresponding to the alkyl group in a complex process. This reaction has been used for analytical determination of primary amino groups in a procedure known as the Van Slyke method.COA of Formula: C6H5ClIN

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Miller, Eric M.; Walczak, Maciej A. published their research in Organic Letters in 2021. The article was titled 《Light-Mediated Cross-Coupling of Anomeric Trifluoroborates》.Quality Control of 3-Iodophenol The article contains the following contents:

Stereoselective reactions at the anomeric carbon constitute the cornerstone of preparative carbohydrate chem. Here, we report stereoselective C-arylation and etherification reactions of anomeric trifluoroborates derived from BMIDA esters. These reactions are characterized by high anomeric selectivities for 2-deoxysugars and broad substrate scope (24 examples), including disaccharides and trifluoroborates with free hydroxyl groups. Taken together, this new class of carbohydrate reagents adds the palette of anomeric nucleophile reagents suitable for efficient installation of C-C bonds. The experimental part of the paper was very detailed, including the reaction process of 3-Iodophenol(cas: 626-02-8Quality Control of 3-Iodophenol)

3-Iodophenol(cas: 626-02-8) belongs to organic iodides. The carbon-iodine bond is weaker than other carbon-halogen bonds due to the poor electronegative nature of the iodine atom. Organic iodides can be alkyl, alkenyl, or alkynyl, and all of them are very reactive toward with many kinds of nucleophiles.Quality Control of 3-Iodophenol

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

《Estimated Survival and Major Comorbidities of Very Preterm Infants Discharged Against Medical Advice vs Treated With Intensive Care in China.》 was written by Jiang, Siyuan; Huang, Xiangyuan; Zhang, Lan; Han, Junyan; Yang, Yi; Wang, Weiping; Lee, Shoo K; Yan, Weili; Cao, Yun; Reduction of Infection in Neonatal Intensive Care Units Using the Evidence-Based Practice for Improving Quality (REIN-EPIQ) Study Group. Safety of 1,2-Diiodoethane And the article was included in JAMA network open in 2021. The article conveys some information:

Importance: A significant proportion of very preterm infants (<32 weeks' gestation) are discharged against medical advice (DAMA) from neonatal intensive care units in China. There is minimal information available on the potential outcomes of providing complete care before discharge in these infants. Objective: To describe potential neonatal outcomes of DAMA in very preterm infants if they receive complete care based on estimates derived from a group of propensity score-matched infants who are not DAMA. Design, Setting, and Participants: This cohort study enrolled all infants born at between 24 and 31 weeks' gestation from May 1, 2015, to April 30, 2018, and admitted to 25 tertiary neonatal intensive care units across China within 7 days of birth. A multilevel mixed-effects logistic regression model was constructed to estimate the propensity score for the likelihood of DAMA for each infant. Infants who were not DAMA were then matched to DAMA infants with the closest propensity score on a 1:1 ratio by using a nearest neighbor greedy matching algorithm without replacement. Incidences of neonatal outcomes were then calculated among the matched non-DAMA infants to simulate the outcomes of DAMA infants. Statistical analyses were performed from August 16, 2020, to September 26, 2020. Exposures: Discharge against medical advice, which was defined as termination of treatment and discharge before the treating physicians recommended discharge. Main Outcomes and Measures: Survival and survival without major morbidity. Results: The study enrolled a total of 14 083 infants (8141 boys [57.8%]) with a median gestational age of 30.1 weeks (interquartile range [IQR], 29.0-31.1 weeks) and a median birth weight of 1400 g (IQR, 1170-1600 g). Overall, 1876 of 14 083 very preterm infants (13.3%; 95% CI, 12.8%-13.9%) were DAMA, of whom 1367 of 1876 (72.9%; 95% CI, 70.8%-74.8%) required intensive care on discharge. A total of 1473 DAMA infants were successfully matched to 1473 non-DAMA infants. Overall, 1211 of 1473 matched non-DAMA infants (82.2%; 95% CI, 80.2%-84.1%) survived to discharge. The survival rates were 68.3% (95% CI, 62.4%-73.7%) for infants at 26 to 27 weeks' gestation, 84.1% (95% CI, 80.7%-87.0%) for infants 28 to 29 weeks' gestation, and 92.4% (95% CI, 90.0%-94.2%) for infants at 30 to 31 weeks' gestation. A total of 872 of 1473 matched non-DAMA infants (59.2%; 95% CI, 56.7%-61.7%) survived without any major morbidity. Conclusions and Relevance: The results of this cohort study suggest that very preterm infants who are DAMA from neonatal intensive care units may have intact survival if complete care is provided. Efforts to reduce DAMA may be associated with improved outcomes of very preterm infants in China. After reading the article, we found that the author used 1,2-Diiodoethane(cas: 624-73-7Safety of 1,2-Diiodoethane)

1,2-Diiodoethane(cas: 624-73-7) is one of organic iodides. Organic iodides are used in veterinary products (Organic Iodide Powder) as a nutritional source of iodine. In the chemical industry, alkyl iodides serve as excellent alkylating agents and, specifically, methyl iodide is used as a methylating agent in the synthesis of various pharmaceutical drugs. Oceanic alkyl iodides are believed to be the principal source of atmospheric iodine.Safety of 1,2-Diiodoethane

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

《Binuclear Palladium Complex Immobilized on Mesoporous SBA-16: Efficient Heterogeneous Catalyst for the Carbonylative Suzuki Coupling Reaction of Aryl Iodides and Arylboronic Acids Using Cr(CO)6 as Carbonyl Source》 was published in Catalysis Letters in 2020. These research results belong to Niakan, Mahsa; Asadi, Zahra; Emami, Mohammad. Application of 624-31-7 The article mentions the following:

A binuclear palladium complex immobilized on organo-functionalized SBA-16 was prepared and structurally characterized by routine techniques. Characterizations indicated that the mesostructure of SBA-16 was maintained after the immobilization of palladium complex. Then, the prepared nanomaterial was applied as a heterogeneous catalyst in the carbonylative Suzuki coupling reaction of aryl iodides RI with arylboronic acids R1B(OH)2 using Cr(CO)6 as carbonyl source to afford diaryl ketones RC(O)R1 [R = Ph, 4-MeC6H4, 4-ClC6H4, 2-H2NC6H4, etc.; R1 = Ph, 4-EtC6H4, 4-F3CC6H4] in excellent yields. Moreover, the catalyst was readily recovered by filtration and could be reused for seven cycles without losing its structural integrity and catalytic activity. The results came from multiple reactions, including the reaction of 1-Iodo-4-methylbenzene(cas: 624-31-7Application of 624-31-7)

1-Iodo-4-methylbenzene(cas: 624-31-7) undergoes Suzuki-Miyaura coupling reaction with phenylboronic acid catalyzed by (Ni,Mg)3Si2O5(OH)4 solid-solution nanotubes loaded with palladium.Application of 624-31-7

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

《Synthesis of (het)aryl 2-(2-hydroxyaryl)cyclopropyl ketones》 was published in Molecules in 2020. These research results belong to Fadeev, Alexander A.; Chagarovskiy, Alexey O.; Makarov, Anton S.; Levina, Irina I.; Ivanova, Olga A.; Uchuskin, Maxim G.; Trushkov, Igor V.. Electric Literature of C3H9IOS The article mentions the following:

A simple general method for the synthesis of 1-acyl-2-(ortho-hydroxyaryl)cyclopropanes I [R = 5-F, 5-NO2, 3-OMe, etc.; Ar = Ph, 4-OMeC6H4, 2-thienyl], which belong to the donor-acceptor cyclopropane family, was developed. This method, based on the Corey-Chaykovsky cyclopropanation of 2-hydroxychalcones, allowed for the preparation of a large diversity of hydroxy-substituted cyclopropanes, which could serve as promising building blocks for the synthesis of various bioactive compounds In addition to this study using Trimethylsulfoxonium iodide, there are many other studies that have used Trimethylsulfoxonium iodide(cas: 1774-47-6Electric Literature of C3H9IOS) was used in this study.

Trimethylsulfoxonium iodide(cas: 1774-47-6) is a sulfoxonium salt. It is used to generate dimethyloxosulfonium methylide by reaction with sodium hydride. The latter compound is used as a methylene-transfer reagent, and is used to prepare epoxides.Electric Literature of C3H9IOS

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

The author of 《Phosphorus corrole complexes: from property tuning to applications in photocatalysis and triplet-triplet annihilation upconversion》 were Mahammed, Atif; Chen, Kepeng; Vestfrid, Jenya; Zhao, Jianzhang; Gross, Zeev. And the article was published in Chemical Science in 2019. Reference of 1-Iodopyrrolidine-2,5-dione The author mentioned the following in the article:

Efficient triplet photosensitizers are important for fundamental photochem. studies and applications such as triplet-triplet annihilation upconversion (TTA UC), photoredox catalytic organic reactions and photovoltaics. We now report a series of phosphorus corrole compounds as efficient visible light-harvesting metal-free triplet photosensitizers. While the heavy-atom-free phosphorus corroles show absorption in the visible spectral region (centered at 573 nm) and have a decent triplet state quantum yield (ΦΔ = 49%), iodo-substitution on the corrole core induces red-shifted absorption (589 nm) and improves intersystem crossing significantly (ΦΔ = 67%). Nanosecond transient absorption spectra confirm triplet state formation upon photoexcitation (τT = 312 μs) and the iodinated derivatives also display near IR phosphorescence in fluid solution at room temperature (λem = 796 nm, τp = 412 μs). Both singlet oxygen (1O2) and superoxide radical anions (O2- ·) may be produced with the phosphorus corroles, which are competent photocatalysts for the oxidative coupling of benzylamine (the Aza Henry reaction). Very efficient TTA UC was observed with the phosphorus corroles as triplet photosensitizers and perylene as the triplet acceptor, with upconversion quantum yields of up to ΦUC = 38.9% (a factor of 2 was used in the equation) and a very large anti-Stokes effect of 0.5 eV. In the experimental materials used by the author, we found 1-Iodopyrrolidine-2,5-dione(cas: 516-12-1Reference of 1-Iodopyrrolidine-2,5-dione)

1-Iodopyrrolidine-2,5-dione(cas: 516-12-1) is used in the preparation of vinyl sulfones from olefins and benzenesulfinic acid. It acts as a source for I+ and involved in Hunsdiecker reactions for the conversion of cinnamic acids, and propiolic acids to the corresponding alfa-halostyrenes and 1-halo-1-alkynes respectively. Reference of 1-Iodopyrrolidine-2,5-dione

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com