Tag: 200-300

The author of 《Iodophenylsulfonates and iodobenzoates as redox-active supporting electrolytes for electrosynthesis》 were Roesel, Arend F.; Broese, Timo; Majek, Michal; Francke, Robert. And the article was published in ChemElectroChem in 2019. Formula: C7H5IO2 The author mentioned the following in the article:

Hypervalent iodine compounds constitute a popular class of reagents in organic chem. Regardless of whether they are generated in situ from an iodoarene precursor with a terminal oxidant or used in stoichiometric amounts, the resulting separation and waste issues are major challenges en route to sustainable and scalable processes. The electrochem. generation of iodine(III) compounds represents an attractive alternative, since elec. current is used as traceless oxidant and unstable or hazardous species are conveniently generated in situ. In this context, we have explored the possibility for the use of iodoarene sulfonates and iodobenzoates as ex-cell mediators for electrosynthesis in 1,1,1,3,3,3-hexafluoroisopropanol. While 2-, 3- and 4-iodobenzoate salts proved to be impractical for various reasons, 2- and 4-iodobenzenesulfonates salts can be selectively oxidized to the iodine(III) species and used for synthetic applications. The ionic tag on the mediator allows for electrolysis without supporting electrolyte additives and enables a straightforward recovery from the product mixture The experimental process involved the reaction of 2-Iodobenzoic acid(cas: 88-67-5Formula: C7H5IO2)

2-Iodobenzoic acid(cas: 88-67-5) belongs to organic iodides. The carbon-iodine bond is weaker than other carbon-halogen bonds due to the poor electronegative nature of the iodine atom. Alkyl iodides react at a faster rate than alkyl fluorides due to the weak C-I bond.Formula: C7H5IO2

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

The author of 《Halogen-containing BODIPY derivatives for photodynamic therapy》 were Gorbe, Monica; Costero, Ana M.; Sancenon, Felix; Martinez-Manez, Ramon; Ballesteros-Cillero, Rafael; Ochando, Luis E.; Chulvi, Katherine; Gotor, Raul; Gil, Salvador. And the article was published in Dyes and Pigments in 2019. Related Products of 516-12-1 The author mentioned the following in the article:

Two iodinated (1 and 2) and two brominated (3 and 4) BODIPY-based photosensitizers are prepared and characterized using slightly modified synthetic procedures previously described. 1-4 present intense absorption bands in the 510-540 nm interval and very weak emissions due to the presence of halogen atoms in their structure. Irradiation of aqueous solutions of 1-4 with visible light (wavelength > 475 nm) induce the generation of singlet oxygen with quantum yields of ca. 0.62-0.66 for the photosensitizers containing iodine atoms (1 and 2) and of ca. 0.16-0.21 for the brominated counterparts (3 and 4). In vitro studies carried out with HeLa, SCC-13 and HaCaT cell lines and the four photosensitizers show marked reductions in cell viability with lower IC50 values for the iodinated derivatives (in the 0.82-2.51 range) than those found for the brominated compounds (in the 0.91-8.26 range) suggesting that these compounds could be used in photodynamic therapy protocols. Subcellular localization studies carried out using confocal microscopy show that photosensitizers accumulated in the endoplasmic reticulum.1-Iodopyrrolidine-2,5-dione(cas: 516-12-1Related Products of 516-12-1) was used in this study.

1-Iodopyrrolidine-2,5-dione(cas: 516-12-1) is used in the preparation of vinyl sulfones from olefins and benzenesulfinic acid. It acts as a source for I+ and involved in Hunsdiecker reactions for the conversion of cinnamic acids, and propiolic acids to the corresponding alfa-halostyrenes and 1-halo-1-alkynes respectively. Related Products of 516-12-1

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

The author of 《Synthesis of Rice Husk Derived Activated Mesoporous Carbon Immobilized Palladium Hybrid Nano-Catalyst for Ligand-Free Mizoroki-Heck/Suzuki/Sonogashira Cross-Coupling Reactions》 were Patel, Ashok Raj; Asatkar, Archana; Patel, Geetika; Banerjee, Subhash. And the article was published in ChemistrySelect in 2019. Electric Literature of C6H4BrI The author mentioned the following in the article:

Chem. activated graphitic mesoporous carbon was synthesized from rice husk biomass and subsequently immobilized with palladium nanoparticles (Pd NPs). The physiochem. characteristics like composition, morphol., structure and textural properties of the rice husk derived activated carbon supported Pd NPs (nano-Pd@RAGC) were analyzed by various anal. and spectroscopic techniques. Finally, the applications of hybrid nano-Pd@RAGC material were investigated in useful carbon-carbon bond forming reactions via Mizoroki-Heck/Suzuki/Sonogashira cross-coupling reactions under ligand-free, microwave conditions. The RAGC provided excellent stability to Pd NPs in cross coupling reactions. The catalyst was recovered simply by filtration and recycled for at least ten times.1-Bromo-4-iodobenzene(cas: 589-87-7Electric Literature of C6H4BrI) was used in this study.

1-Bromo-4-iodobenzene(cas: 589-87-7) is mainly used as the OLED pharmaceutical intermediate, as reagent for in situ desilylation and coupling of silylated alkynes, as substrate in copper-free Sonogashira coupling in aqueous acetone..Electric Literature of C6H4BrI It is also used in synthesis of β,β,dibromostyrenes, as starting reagent in the total syntheses of ent-conduramine A and ent-7-deoxypancratistatin (alkaloids)

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

The author of 《A modular approach to prepare enantioenriched cyclobutanes: synthesis of (+)-rumphellaone A》 were Beck, Jordan C.; Lacker, Caitlin R.; Chapman, Lauren M.; Reisman, Sarah E.. And the article was published in Chemical Science in 2019. Application of 624-31-7 The author mentioned the following in the article:

A modular synthesis of enantioenriched polyfunctionalized cyclobutanes I [Ar = 4-MeC6H4, 3-F3CC6H4, 2-fluoro-3-pyridyl, etc.] was developed via Pd-catalyzed C-H arylation of 8-aminoquinolinamide with aryl iodides. The C-H arylation products I were derivatized through subsequent decarboxylative coupling processes. This synthetic strategy enabled a 9-step enantioselective total synthesis of the antiproliferative meroterpenoid (+)-rumphellaone A.1-Iodo-4-methylbenzene(cas: 624-31-7Application of 624-31-7) was used in this study.

1-Iodo-4-methylbenzene(cas: 624-31-7) is used in wide range of medicals industrial applications as well as in pharmaceutical intermediates, polarizing films for Liquid Crystal Display (LCD) chemicals.Application of 624-31-7

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

The author of 《Diethynyldiazafluoren-9-ylidene as a π Cross-Conjugated Platform for Redox Active Transition Metal Fragments》 were Nauroozi, Djawed; Bruhn, Clemens; Faust, Ruediger. And the article was published in Organometallics in 2019. Recommanded Product: 1-Bromo-4-iodobenzene The author mentioned the following in the article:

Synthetic routes were developed to attach three redox-active metal fragments to cross-conjugated 3-methylidenepentadiyne covalently expanded by diazafluorenylidene: The two alkyne termini of this new ligand were end-capped via a phenylene spacer with ethynyl ferrocene, and a [Ru(bpy)2]2+ fragment was coordinated in the diimine binding site. The photophys. and electrochem. properties of both the diferrocenyl-terminated ligand and its corresponding Ru-complex were investigated by UV-vis absorption spectroscopy and cyclic voltammetry. The absorption data reveal significant interactions of the metal centers with the cross-conjugated ligand system. In the electrochem. experiments the ferrocenyl and the ruthenium centers could be addressed individually as they are separated by almost 1 V. While the presence of the Ru-fragment manifests itself in the reduction potential of the diazafluorenylidene-ligand, communication between the ferrocenyl end-caps on one hand and between the ferrocenes and the Ru-fragment on the other appears to be reduced through the freely rotating phenylene spacers. The results came from multiple reactions, including the reaction of 1-Bromo-4-iodobenzene(cas: 589-87-7Recommanded Product: 1-Bromo-4-iodobenzene)

1-Bromo-4-iodobenzene(cas: 589-87-7) has been employed as reagent for in situ desilylation and coupling of silylated alkynes, as starting reagent in the total syntheses of ent-conduramine A and ent-7-deoxypancratistatin (alkaloids), as substrate in copper-free Sonogashira coupling in aqueous acetone in synthesis of β,β,dibromostyrenesRecommanded Product: 1-Bromo-4-iodobenzene

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

In 2019,Organic Letters included an article by Jiang, Huanfeng; Zhang, Hao; Xiong, Wenfang; Qi, Chaorong; Wu, Wanqing; Wang, Lu; Cheng, Ruixiang. Application In Synthesis of Trimethylsulfoxonium iodide. The article was titled 《Iridium-Catalyzed Three-component Coupling Reaction of Carbon Dioxide, Amines, and Sulfoxonium Ylides》. The information in the text is summarized as follows:

The first iridium-catalyzed three-component coupling reaction of carbon dioxide, amines, and sulfoxonium ylides has been developed, providing an efficient and straightforward method for the construction of a range of structurally diverse O-β-oxoalkyl carbamates, e.g., I (X-rays single crystal structure shown), in moderate to excellent yields. This novel protocol features the use of readily available substrates, wide substrate scope, and good functional group tolerance. Moreover, the phosgene-free strategy was successfully applied to the synthesis of a potential antitumor agent via a a three-step procedure starting from a steroid carboxylic acid. In the experiment, the researchers used many compounds, for example, Trimethylsulfoxonium iodide(cas: 1774-47-6Application In Synthesis of Trimethylsulfoxonium iodide)

Trimethylsulfoxonium iodide(cas: 1774-47-6) reacts with sodium hydride to prepare dimethyloxosulfonium methylide, which is used as a methylene-transfer reagent in synthetic chemistry. It is used to prepare ylide, which reacts with carbonyl compounds to get epoxides. Further, it reacts with alfa,beta-unsaturated esters to get cyclopropyl esters.Application In Synthesis of Trimethylsulfoxonium iodide

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

In 2019,Chemical Science included an article by Caramenti, Paola; Declas, Nina; Tessier, Romain; Wodrich, Matthew D.; Waser, Jerome. Recommanded Product: 2-Iodobenzoic acid. The article was titled 《Stereoselective synthesis of alkyl-, aryl-, vinyl- and alkynyl-substituted Z-enamides and enol ethers》. The information in the text is summarized as follows:

Enamides and enol ethers are valuable building blocks in synthetic chem., yet their stereoselective synthesis can be challenging. Herein, authors report a new stereoselective synthesis of vinyl, aryl, alkynyl, alkyl and thio-substituted Z-enamides and enol ethers based on the use of vinylbenziodoxolone (VBX) reagents. The stable VBX reagents were synthesized by stereoselective addition of N- or O-nucleophiles on the corresponding alkynyl reagents in the presence of a catalytic amount of cesium carbonate. The VBX reagents were used in palladium-catalyzed cross-couplings at room temperature to access Z-enamides and enol ethers. After reading the article, we found that the author used 2-Iodobenzoic acid(cas: 88-67-5Recommanded Product: 2-Iodobenzoic acid)

2-Iodobenzoic acid(cas: 88-67-5) belongs to organic iodides. Organic iodides are used in veterinary products (Organic Iodide Powder) as a nutritional source of iodine.Recommanded Product: 2-Iodobenzoic acid In the chemical industry, alkyl iodides serve as excellent alkylating agents and, specifically, methyl iodide is used as a methylating agent in the synthesis of various pharmaceutical drugs.

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

In 2017,Ikai, Tomoyuki; Suzuki, Daisuke; Shinohara, Ken-ichi; Maeda, Katsuhiro; Kanoh, Shigeyoshi published 《A cellulose-based chiral fluorescent sensor for aromatic nitro compounds with central, axial and planar chirality》.Polymer Chemistry published the findings.Category: iodides-buliding-blocks The information in the text is summarized as follows:

Chiral sensing using fluorescent responses as output signals is an attractive technique for enantiodifferentiation in terms of its rapidity, high sensitivity, simplicity and high-throughput ability. However, because the reported sensors can only be applied to a limited type of chiral mol. (mainly compounds with a chiral center), it is still a great challenge to develop a powerful fluorescent sensor applicable to various types of chirality. Herein, we synthesized a novel chiral fluorescent sensor (Ce-3) containing a benzo[1,2-b:4,5-b]dithiophene-based π-conjugated group as a fluorescent signaling unit through a two-step polymer reaction, including carbamoylation and cross-coupling reactions, using microcrystalline cellulose as a starting material. The enantioselective fluorescence response of this modified cellulose to aromatic nitro compounds was investigated in solution and in the solid state. Ce-3 exhibited enantioselective fluorescence quenching for a wide range of aromatic nitro compounds with central, axial and planar chirality. Visual chiral detection based on a change of the visible emission color was also achieved with Ce-3 in conjunction with anthracene as an achiral fluorescent dye. A corresponding model mol. did not show any marked sensing ability, suggesting that the regular higher-order structure of Ce-3 plays a key role in this efficient chiral sensing. The results came from multiple reactions, including the reaction of 1,2-Diiodoethane(cas: 624-73-7Category: iodides-buliding-blocks)

1,2-Diiodoethane(cas: 624-73-7) is one of organic iodides. Organic iodides are used in veterinary products (Organic Iodide Powder) as a nutritional source of iodine. In the chemical industry, alkyl iodides serve as excellent alkylating agents and, specifically, methyl iodide is used as a methylating agent in the synthesis of various pharmaceutical drugs. Oceanic alkyl iodides are believed to be the principal source of atmospheric iodine.Category: iodides-buliding-blocks

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

In 2015,Vitaku, Edon; Njardarson, Jon T. published 《Formation of fused aromatic architectures via an oxidative dearomatization-radical cyclization rearomatization approach》.Tetrahedron Letters published the findings.Recommanded Product: 624-73-7 The information in the text is summarized as follows:

A new mild C-C bond forming cyclization approach of catechol derivatives is reported. This approach relies on an initial dearomatization step using lead(IV) acetate followed by a carefully controlled radical cyclization step, which under the reaction conditions also facilitates rearomatization. Triethylborane is key to the success of this reaction as it enables the reaction to proceed at low temperatures and is also believed to aid rearomatization. The amount and ratio of triethylborane and reducing agent (tributyltinhydride) that is employed as well as the concentration the reaction is run at are all essential to the success of this new approach.1,2-Diiodoethane(cas: 624-73-7Recommanded Product: 624-73-7) was used in this study.

1,2-Diiodoethane(cas: 624-73-7) is one of organic iodides. The carbon-iodine bond is weaker than other carbon-halogen bonds due to the poor electronegative nature of the iodine atom. In general, organic iodides are light-sensitive and turn yellow during storage, owing to the formation of iodine. Organic iodides can be alkyl, alkenyl, or alkynyl, and all of them are very reactive toward with many kinds of nucleophiles.Recommanded Product: 624-73-7

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

In 2020,Liquid Crystals included an article by Cigl, Martin; Jurok, Radek; Hampl, Frantisek; Svoboda, Jiri; Podoliak, Natalia; Novotna, Vladimira. COA of Formula: C8H6ClIO2. The article was titled 《Lateral substituted phenyl biphenylcarboxylates – non-chiral analogues of ferroelectric liquid crystals》. The information in the text is summarized as follows:

In this study mesomorphic properties of non-chiral liquid crystalline mols. and study the effect of lateral halogen (fluoro, chloro) substitution in the mol. core and the length of terminal chains was reported. This study prepared nine homolog series with the mol. core substituted at different positions with respect to the ester linkage group. Addnl., this study modified the length of both terminal alkyl chains (hexyl, octyl, decyl and dodecyl) sym. for both terminal chains. The effects of the lateral substitution and the chain length were analyzed with respect of the possibility to reduce the transition temperatures and tune the properties of presented liquid crystalline mols. The experimental part of the paper was very detailed, including the reaction process of Methyl 3-chloro-4-iodobenzoate(cas: 874569-39-8COA of Formula: C8H6ClIO2)

Methyl 3-chloro-4-iodobenzoate(cas: 874569-39-8) belongs to organic iodides. Alkyl iodides react at a faster rate than alkyl fluorides due to the weak C-I bond.Iodo alkanes participate in a variety of organic synthesis reactions, which include the Simmons–Smith reaction (cyclopropanation using iodomethane), Williamson ether synthesis, Wittig reaction, Grignard reaction, alkyl coupling reactions, and Wurtz reaction.COA of Formula: C8H6ClIO2

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com