Tag: 200-300

Rodrigues Silva, Daniela; de Azevedo Santos, Lucas; Hamlin, Trevor A.; Fonseca Guerra, Celia; Freitas, Matheus P.; Bickelhaupt, F. Matthias published their research in ChemPhysChem in 2021. The article was titled 《The Gauche Effect in XCH2CH2X Revisited》.SDS of cas: 624-73-7 The article contains the following contents:

We have quantum chem. investigated the rotational isomerism of 1,2-dihaloethanes XCH2CH2X (X = F, Cl, Br, I) at ZORA-BP86-D3(BJ)/QZ4P. Our Kohn-Sham MO (KS-MO) analyses reveal that hyperconjugative orbital interactions favor the gauche conformation in all cases (X = F-I), not only for X = F as in the current model of this so-called gauche effect. We show that, instead, it is the interplay of hyperconjugation with Pauli repulsion between lone-pair-type orbitals on the halogen substituents that constitutes the causal mechanism for the gauche effect. Thus, only in the case of the relatively small fluorine atoms, steric Pauli repulsion is too weak to overrule the gauche preference of the hyperconjugative orbital interactions. For the larger halogens, X···X steric Pauli repulsion becomes sufficiently destabilizing to shift the energetic preference from gauche to anti, despite the opposite preference of hyperconjugation. The results came from multiple reactions, including the reaction of 1,2-Diiodoethane(cas: 624-73-7SDS of cas: 624-73-7)

1,2-Diiodoethane(cas: 624-73-7) is one of organic iodides. Alkyl iodides react at a faster rate than alkyl fluorides due to the weak C-I bond. Iodo alkanes participate in a variety of organic synthesis reactions, which include the Simmons–Smith reaction (cyclopropanation using iodomethane), Williamson ether synthesis, Wittig reaction, Grignard reaction, alkyl coupling reactions, and Wurtz reaction.SDS of cas: 624-73-7

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Points, Gary L. III; Beaudry, Christopher M. published their research in Organic Letters in 2021. The article was titled 《Regioselective Synthesis of Substituted Carbazoles, Bicarbazoles, and Clausine C》.Synthetic Route of C6H5ClIN The article contains the following contents:

Substituted carbazoles are efficiently constructed from 3-triflato-2-pyrones and alkynyl anilines. Multiple substituents are tolerated on the carbazole, and complete control of regiochem. is observed Complicated and sterically congested substitution patterns are produced. This strategy is also used to prepare substituted bicarbazoles and related biaryls. Finally, the method was showcased in a synthesis of the carbazole natural product clausine C. In the part of experimental materials, we found many familiar compounds, such as 4-Chloro-2-iodoaniline(cas: 63069-48-7Synthetic Route of C6H5ClIN)

4-Chloro-2-iodoaniline(cas: 63069-48-7) belongs to anime. Acylation is one of the most important reactions of primary and secondary amines; a hydrogen atom is replaced by an acyl group (a group derived from an acid, such as RCOOH or RSO3H, by removal of ―OH, such as RC(=O)―, RS(O)2―, and so on). Reagents may be acid chlorides (RCOC1, RSO2C1), anhydrides ((RCO)2O), or even esters (RCOOR′); the products are amides of the corresponding acids.Synthetic Route of C6H5ClIN

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Horan, Alexandra M.; Duong, Vincent K.; McGarrigle, Eoghan M. published their research in Organic Letters in 2021. The article was titled 《Synthesis of Bis-heteroaryls Using Grignard Reagents and Pyridylsulfonium Salts》.Formula: C5H4IN The article contains the following contents:

Herein ligand-coupling reactions of Grignard reagents with pyridylsulfonium salts I (R = H, Br, Me, trifluoromethyl; R1 = H, OMe, CN, Br, etc.; R2 = H, trifluoromethyl; R3 = H, Me; R2R3 = -(CH=CH-CH=CH)-) and phenyl(pyrimidin-2-yl)(p-tolyl)sulfonium trifluoromethanesulfonate are reported. The method has wide functional group tolerance and enables the formation of bis-heterocycle linkages including 2,4′-bipyridines, 2,3′-bipyridines, and 2,2′-bipyridines, as well as pyridines linked to pyrimidines, pyrazines, isoxazoles, and benzothiophenes II (R4 = 2-fluoropyridin-4-yl, pyrazin-2-yl, dimethyl-1,2-oxazol-4-yl, 1-benzothiophen-2-yl, etc.). The methodol. was successfully applied to the synthesis of the natural products caerulomycin A and E. In the experiment, the researchers used many compounds, for example, 4-Iodopyridine(cas: 15854-87-2Formula: C5H4IN)

4-Iodopyridine(cas: 15854-87-2) belongs to pyridine. Pyridine’s structure is isoelectronic with that of benzene, but its properties are quite different. Pyridine is completely miscible with water, whereas benzene is only slightly soluble. Like all hydrocarbons, benzene is neutral (in the acid–base sense), but because of its nitrogen atom, pyridine is a weak base.Formula: C5H4IN

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

《The Reactivity of Phosphanylphosphinidene Complexes of Transition Metals Toward Terminal Dihaloalkanes》 was written by Ordyszewska, Anna; Szynkiewicz, Natalia; Chojnacki, Jaroslaw; Pikies, Jerzy; Grubba, Rafal. Safety of 1,2-Diiodoethane And the article was included in Inorganic Chemistry in 2020. The article conveys some information:

The reactivities of phosphanylphosphinidene complexes [(DippN)2W(Cl)(η2-P-PtBu2)]- (1), [(pTol3P)2Pt(η2-P:PtBu2)] (2), and [(dppe)Pt(η2-P:PtBu2)] (3) toward dihaloalkanes and Me iodide were investigated. The reactions of the anionic tungsten complex (1) with stoichiometric Br(CH2)nBr (n = 3, 4, 6) led to the formation of neutral complexes with a tBu2PP(CH2)3Br ligand or neutral dinuclear complexes with unusual tetradentate tBu2PP(CH2)nPPtBu2 ligands (n = 4, 6). The methylation of platinum complexes 2 and 3 with MeI yielded neutral or cationic complexes bearing side-on coordinated tBu2P-P-Me moieties. The reaction of 2 with I(CH2)2I gave a platinum complex with a tBu2P-P-I ligand. When the same dihaloalkane was reacted with 3, the P-P bond in the phosphanylphosphinidene ligand was cleaved to yield tBu2PI, phosphorus polymers, [(dppe)PtI2] and C2H4. Furthermore, the reaction of 3 with Br(CH2)2Br yielded dinuclear complex bearing a tetraphosphorus tBu2PPPPtBu2 ligand in the coordination sphere of the platinum. The mol. structures of the isolated products were established in the solid state and in solution by single-crystal x-ray diffraction and NMR spectroscopy. DFT studies indicated that the polyphosphorus ligands in the obtained complexes possess structures similar to free phosphenium cations tBu2P+:P-R (R = Me, I) or (tBu2P+:P)2. The phosphanylphosphinidene complexes of tungsten and platinum as building blocks for syntheses of polydentate phosphorus ligands. In the experiment, the researchers used 1,2-Diiodoethane(cas: 624-73-7Safety of 1,2-Diiodoethane)

1,2-Diiodoethane(cas: 624-73-7) is one of organic iodides. The carbon-iodine bond is weaker than other carbon-halogen bonds due to the poor electronegative nature of the iodine atom. In general, organic iodides are light-sensitive and turn yellow during storage, owing to the formation of iodine. Organic iodides can be alkyl, alkenyl, or alkynyl, and all of them are very reactive toward with many kinds of nucleophiles.Safety of 1,2-Diiodoethane

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

《Sustainable and recyclable heterogenous palladium catalysts from rice husk-derived biosilicates for Suzuki-Miyaura cross-couplings, aerobic oxidations and stereoselective cascade carbocyclizations》 was written by Afewerki, Samson; Franco, Ana; Balu, Alina M.; Tai, Cheuk-Wai; Luque, Rafael; Cordova, Armando. Product Details of 15854-87-2 And the article was included in Scientific Reports in 2020. The article conveys some information:

Abstract: A new eco-friendly approach for the preparation of sustainable heterogeneous palladium catalysts from rice husk-derived biogenic silica (RHP-Si and RHU-Si). The designed heterogeneously supported palladium species (RHP-Si-NH2-Pd and RHU-Si-NH2-Pd) were fully characterized and successfully employed as catalysts for various chem. transformations (C-C bond-forming reactions, aerobic oxidations and carbocyclizations). Suzuki-Miyaura transformations were highly efficient in a green solvent system (H2O:EtOH (1:1) with excellent recyclability, providing the cross-coupling products with a wide range of functionalities in high isolated yields (up to 99%). Palladium species (Pd(0)-nanoparticles or Pd(II)) were also efficient catalysts in the green aerobic oxidation of an allylic alc. and a co-catalytic stereoselective cascade carbocyclization transformation. In the latter case, a quaternary stereocenter was formed with excellent stereoselectivity (up to 27:1 dr). In the experiment, the researchers used many compounds, for example, 4-Iodopyridine(cas: 15854-87-2Product Details of 15854-87-2)

4-Iodopyridine(cas: 15854-87-2) is used as a reagent in the synthesis of indazolylamides as glucocorticoid receptor agonists. 4-Iodopyridine is a halogenated heterocycle that is a building block for proteomics research.Product Details of 15854-87-2

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

《Mo, Co co-doped NiS bulks supported on Ni foam as an efficient electrocatalyst for overall water splitting in alkaline media》 was written by Wu, Caiyun; Du, Yunmei; Fu, Yunlei; Feng, Di; Li, Hui; Xiao, Zhenyu; Liu, Yanru; Yang, Yu; Wang, Lei. Application In Synthesis of 1-Iodopyrrolidine-2,5-dione And the article was included in Sustainable Energy & Fuels in 2020. The article conveys some information:

In this study, a composite of Mo, Co co-doped NiS bulks grown on an Ni foam (Mo,Co-NiS/NF) was synthesized as a bi-functional electrocatalyst for hydrogen evolution reaction (HER) and oxygen evolution reaction (OER) using a simple method. The existence of ZIF-67 and Mo ensure the even distribution of Co and Mo elements and the formation of N doped carbon layer in Mo, Co-NiS/NF. Mo, Co co-doping and NF support greatly improved the electrocatalytic performance of NiS bulks, because metal element doping could improve the intrinsic activity and elec. conductivity Moreover, the Ni foam could act as a substrate to avoid aggregation and provide nickel source to form the bimetallic sulfide. The product Mo,Co-NiS/NF-400 showed outstanding electrochem. properties, with ultralow overpotential (92 mV vs. RHE) for HER and ultralow overpotential (117.2 mV vs. RHE) for OER to achieve 10 mA cm-2, as well as the ultralow cell voltage (1.36 V) to achieve 20 mA cm-2 for overall water splitting. This study provides an available method to promote the electrocatalytic activity of the traditional monometallic sulfides for overall water splitting. In the experiment, the researchers used many compounds, for example, 1-Iodopyrrolidine-2,5-dione(cas: 516-12-1Application In Synthesis of 1-Iodopyrrolidine-2,5-dione)

1-Iodopyrrolidine-2,5-dione(cas: 516-12-1) is used in the preparation of vinyl sulfones from olefins and benzenesulfinic acid. It acts as a source for I+ and involved in Hunsdiecker reactions for the conversion of cinnamic acids, and propiolic acids to the corresponding alfa-halostyrenes and 1-halo-1-alkynes respectively. Application In Synthesis of 1-Iodopyrrolidine-2,5-dione

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

《Transition-metal influence (Fe, Co, Ni, Cu) on the MoWS catalyst for biphenyl hydrogenation》 was written by Olivas, A.; Gaxiola, E.; Cruz-Reyes, J.; Alvarez-Amparan, M. A.; Valdez, R.. Computed Properties of C4H4INO2 And the article was included in Fuel Processing Technology in 2020. The article conveys some information:

The hydrogenation of aromatic hydrocarbon compounds derived of hydrocarbon fuels is crucial to avoid the current environment pollution, harmful to human health. Also, the hydrogenated products can be used as chem. intermediates, additives, and in other chem. processes. The search of efficient and cost-effective catalysts for the hydrogenation of aromatic hydrocarbon compounds is a current challenge in the industrial and scientific community. In this study, trimetallic unsupported MMoW (M = Fe, Co, Ni, and Cu) sulfide catalysts were synthesized and tested in the liquid-phase biphenyl (BP) hydrogenation at 300 °C and 5.5 MPa of H2 pressure. The catalysts were characterized by XRD, SEM-EDX, TEM-SAED and adsorption-desorption of N2. The presence of NiS, CoSx, MoFe2S4, Cu9S5 crystalline sulfide phases together with Mo(W)S2 crystalline sulfide phase, as well as the crystallite size and the surface area, influenced the catalytic performance. Ni-based catalysts were the most active in the BP hydrogenation. A BP conversion value of ∼99% of biphenyl and selectivity of 52% towards cyclohexylbenzene (CHB) and 47% towards bicyclohexyl were reached using NiMoWS catalyst. The presence of NiS crystals, stacked curve-shape Mo(W)S2 crystalline phases and larger surface area values increased the catalytic activity using NiMoWS catalysts. The experimental process involved the reaction of 1-Iodopyrrolidine-2,5-dione(cas: 516-12-1Computed Properties of C4H4INO2)

1-Iodopyrrolidine-2,5-dione(cas: 516-12-1) is used in the preparation of vinyl sulfones from olefins and benzenesulfinic acid. It acts as a source for I+ and involved in Hunsdiecker reactions for the conversion of cinnamic acids, and propiolic acids to the corresponding alfa-halostyrenes and 1-halo-1-alkynes respectively. Computed Properties of C4H4INO2

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

《Photocatalytic Umpolung of N- and O-substituted alkenes for the synthesis of 1,2-amino alcohols and diols》 was written by Amos, Stephanie G. E.; Nicolai, Stefano; Waser, Jerome. Formula: C7H5IO2 And the article was included in Chemical Science in 2020. The article conveys some information:

An organophotocatalytic 1,2-oxyalkynylation of ene-carbamates and enol ethers using ethynyl benziodoxolones (EBXs). 1-alkynyl-1,2-amino alcs. and diols were obtained in up to 89% yield was reported. Photocatalytic formation of radical cations led to Umpolung of the innate reactivity of the alkenes, enabled addition of a nucleophilic benzoate followed by radical alkynylation.2-Iodobenzoic acid(cas: 88-67-5Formula: C7H5IO2) was used in this study.

2-Iodobenzoic acid(cas: 88-67-5) belongs to organic iodides.Formula: C7H5IO2 The carbon-iodine bond is weaker than other carbon-halogen bonds due to the poor electronegative nature of the iodine atom. In general, organic iodides are light-sensitive and turn yellow during storage, owing to the formation of iodine.

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

《Synthesis of the tetrasaccharide repeating unit of the O-antigen from Pseudomonas putida BIM B-1100 having rare D-Quip3NAc》 was published in Carbohydrate Research in 2020. These research results belong to Bera, Madhumita; Mukhopadhyay, Balaram. HPLC of Formula: 516-12-1 The article mentions the following:

Chem. synthesis of the complex tetrasaccharide repeating unit of the O-antigen from Pseudomonas putida BIM B-1100 is accomplished in the form of its 2-aminoethyl glycoside to leave the scope for further glycoconjugate formation without hampering the anomeric stereochem. A [2 + 2] strategy is followed to complete the total synthesis and a late stage TEMPO mediated oxidation is used to install the required uronic acid. A radical mediated 6-deoxygenation with subsequent protecting group manipulation strategy is used for the preparation of the rare D-FucpNAc and D-Quip3NAc derivatives from suitable D-glucosamine derivatives The results came from multiple reactions, including the reaction of 1-Iodopyrrolidine-2,5-dione(cas: 516-12-1HPLC of Formula: 516-12-1)

1-Iodopyrrolidine-2,5-dione(cas: 516-12-1) is used in the preparation of vinyl sulfones from olefins and benzenesulfinic acid. It acts as a source for I+ and involved in Hunsdiecker reactions for the conversion of cinnamic acids, and propiolic acids to the corresponding alfa-halostyrenes and 1-halo-1-alkynes respectively. HPLC of Formula: 516-12-1

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

The author of 《Plasmonic catalysis for the Suzuki-Miyaura cross-coupling reaction using palladium nanoflowers》 were Sarhid, Iyad; Abdellah, Ibrahim; Martini, Cyril; Huc, Vincent; Dragoe, Diana; Beaunier, Patricia; Lampre, Isabelle; Remita, Hynd. And the article was published in New Journal of Chemistry in 2019. COA of Formula: C7H7I The author mentioned the following in the article:

Plasmonic catalysis enables the realization of reactions using solar light with less energy and time consumption. Pd nanoflowers synthesized by a radiolytic reduction of PdII(acac)2 in ethanol under a CO atm. exhibit a broad plasmon band in the visible-near IR domain. These plasmonic nanostructures showed remarkably enhanced the photocatalytic activity for Suzuki-Miyaura reactions under visible light irradiation In the experimental materials used by the author, we found 1-Iodo-4-methylbenzene(cas: 624-31-7COA of Formula: C7H7I)

1-Iodo-4-methylbenzene(cas: 624-31-7) is used in wide range of medicals industrial applications as well as in pharmaceutical intermediates, polarizing films for Liquid Crystal Display (LCD) chemicals.COA of Formula: C7H7I

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com